Discovery of a rich proto-cluster at z=2.9 and associated diffuse cold gas in the VIMOS Ultra-Deep Survey (VUDS)

[Abridged] We characterise a massive proto-cluster at z=2.895 that we found in the COSMOS field using the spectroscopic sample of the VIMOS Ultra-Deep Survey (VUDS). This is one of the rare structures at z~3 not identified around AGNs or radio galaxies, so it is an ideal laboratory to study galaxy formation in dense environments. The structure comprises 12 galaxies with secure spectroscopic redshift in an area of 7'x8', in a z bin of Dz=0.016. The measured galaxy number overdensity is delta_g=12+/-2. This overdensity has total mass of M~8.1x10^(14)M_sun in a volume of 13x15x17 Mpc^3. Simulations indicate that such an overdensity at z~2.9 is a proto-cluster that will collapse in a cluster of total mass M~2.5x10^(15)M_sun at z=0. We compare the properties of the galaxies within the overdensity with a control sample at the same z but outside the overdensity. We did not find any statistically significant difference between the properties (stellar mass, SFR, sSFR, NUV-r, r-K) of the galaxies inside and outside the overdensity. The stacked spectrum of galaxies in the overdensity background shows a significant absorption feature at the wavelength of Lya redshifted at z=2.895 (lambda=4736 A), with a rest frame EW = 4+/- 1.4 A. Stacking only background galaxies without intervening sources at z~2.9 along their line of sight, we find that this absorption feature has a rest frame EW of 10.8+/-3.7 A, with a detection S/N of ~4. These EW values imply a high column density (N(HI)~3-20x10^(19)cm^(-2)), consistent with a scenario where such absorption is due to intervening cold gas streams, falling into the halo potential wells of the proto-cluster galaxies. However, we cannot exclude the hypothesis that this absorption is due to the diffuse gas within the overdensity.Comment: 15 pages, 9 figures, accepted for publication in A&A (revised version after referee's comments and language editing

The VIMOS Ultra Deep Survey First Data Release: spectra and spectroscopic redshifts of 698 objects up to z~6 in CANDELS

This paper describes the first data release (DR1) of the VIMOS Ultra Deep Survey (VUDS). The DR1 includes all low-resolution spectroscopic data obtained in 276.9 arcmin2 of the CANDELS-COSMOS and CANDELS-ECFDS survey areas, including accurate spectroscopic redshifts z_spec and individual spectra obtained with VIMOS on the ESO-VLT. A total of 698 objects have a measured redshift, with 677 galaxies, two type-I AGN and a small number of 19 contaminating stars. The targets of the spectroscopic survey are selected primarily on the basis of their photometric redshifts to ensure a broad population coverage. About 500 galaxies have z_spec>2, 48 with z_spec>4, and the highest reliable redshifts reach beyond z_spec=6. This dataset approximately doubles the number of galaxies with spectroscopic redshifts at z>3 in these fields. We discuss the general properties of the sample in terms of the spectroscopic redshift distribution, the distribution of Lyman-alpha equivalent widths, and physical properties including stellar masses M_star and star formation rates (SFR) derived from spectral energy distribution fitting with the knowledge of z_spec. We highlight the properties of the most massive star-forming galaxies, noting the large range in spectral properties, with Lyman-alpha in emission or in absorption, and in imaging properties with compact, multi-component or pair morphologies. We present the catalogue database and data products. All data are publicly available and can be retrieved from a dedicated query-based database available at http://cesam.lam.fr/vuds.Comment: 11 pages, 6 figures, submitted to A&

The Lyman Continuum escape fraction of galaxies at z=3.3 in the VUDS-LBC/COSMOS field

The Lyman continuum (LyC) flux escaping from high-z galaxies into the IGM is a fundamental quantity to understand the physical processes involved in the reionization epoch. We have investigated a sample of star-forming galaxies at z~3.3 in order to search for possible detections of LyC photons escaping from galaxy halos. UV deep imaging in the COSMOS field obtained with the prime focus camera LBC at the LBT telescope was used together with a catalog of spectroscopic redshifts obtained by the VIMOS Ultra Deep Survey (VUDS) to build a sample of 45 galaxies at z~3.3 with L>0.5L*. We obtained deep LBC images of galaxies with spectroscopic redshifts in the interval 3.27<z<3.40 both in the R and deep U bands. A sub-sample of 10 galaxies apparently shows escape fractions>28% but a detailed analysis of their properties reveals that, with the exception of two marginal detections (S/N~2) in the U band, all the other 8 galaxies are most likely contaminated by the UV flux of low-z interlopers located close to the high-z targets. The average escape fraction derived from the stacking of the cleaned sample was constrained to fesc_rel<2%. The implied HI photo-ionization rate is a factor two lower than that needed to keep the IGM ionized at z~3, as observed in the Lyman forest of high-z QSO spectra or by the proximity effect. These results support a scenario where high redshift, relatively bright (L>0.5L*) star-forming galaxies alone are unable to sustain the level of ionization observed in the cosmic IGM at z~3. Star-forming galaxies at higher redshift and at fainter luminosities (L<<L*) can be the major contributors to the reionization of the Universe only if their physical properties are subject to rapid changes from z~3 to z~6-10. Alternatively, ionizing sources could be discovered looking for fainter sources among the AGN population at high-z.Comment: 21 pages, 9 figures. Accepted for publication in A&

DustPedia: Multiwavelength photometry and imagery of 875 nearby galaxies in 42 ultraviolet-microwave bands

Aims. The DustPedia project is capitalising on the legacy of the Herschel Space Observatory, using cutting-edge modelling techniques to study dust in the 875 DustPedia galaxies – representing the vast majority of extended galaxies within 3000 km s-1 that were observed by Herschel. This work requires a database of multiwavelength imagery and photometry that greatly exceeds the scope (in terms of wavelength coverage and number of galaxies) of any previous local-Universe survey. Methods. We constructed a database containing our own custom Herschel reductions, along with standardised archival observations from GALEX, SDSS, DSS, 2MASS, WISE, Spitzer, and Planck. Using these data, we performed consistent aperture-matched photometry, which we combined with external supplementary photometry from IRAS and Planck. Results. We present our multiwavelength imagery and photometry across 42 UV-microwave bands for the 875 DustPedia galaxies. Our aperture-matched photometry, combined with the external supplementary photometry, represents a total of 21 857 photometric measurements. A typical DustPedia galaxy has multiwavelength photometry spanning 25 bands. We also present the Comprehensive & Adaptable Aperture Photometry Routine (CAAPR), the pipeline we developed to carry out our aperture-matched photometry. CAAPR is designed to produce consistent photometry for the enormous range of galaxy and observation types in our data. In particular, CAAPR is able to determine robust cross-compatible uncertainties, thanks to a novel method for reliably extrapolating the aperture noise for observations that cover a very limited amount of background. Our rich database of imagery and photometry is being made available to the community

The resolved scaling relations in DustPedia: Zooming in on the local Universe

We perform a homogeneous analysis of an unprecedented set of spatially resolved scaling relations (SRs) between ISM components and other properties in the range of scales 0.3-3.4 kpc. We also study some ratios: dust-to-stellar, dust-to-gas, and dust-to-metal. We use a sample of 18 large, spiral, face-on DustPedia galaxies. All the SRs are moderate/strong correlations except the dust-HI SR that does not exist or is weak for most galaxies. The SRs do not have a universal form but each galaxy is characterized by distinct correlations, affected by local processes and galaxy peculiarities. The SRs hold starting from 0.3 kpc, and if a breaking down scale exists it is < 0.3 kpc. By evaluating all galaxies at 3.4 kpc, differences due to peculiarities of individual galaxies are cancelled out and the corresponding SRs are consistent with those of whole galaxies. By comparing subgalactic and global scales, the most striking result emerges from the SRs involving ISM components: the dust-total gas SR is a good correlation at all scales, while the dust-H2 and dust-HI SRs are good correlations at subkpc/kpc and total scales, respectively. For the other explored SRs, there is a good agreement between small and global scales and this may support the picture where the main physical processes regulating the properties and evolution of galaxies occur locally. Our results are consistent with the hypothesis of self-regulation of the SF process. The analysis of subgalactic ratios shows that they are consistent with those derived for whole galaxies, from low to high z, supporting the idea that also these ratios could be set by local processes. Our results highlight the heterogeneity of galaxy properties and the importance of resolved studies on local galaxies in the context of galaxy evolution. They also provide observational constraints to theoretical models and updated references for high-z studies.Comment: 42 pages, 11 figures and 5 tables in the main text, 2 figures and 1 table in Appendix. Accepted for publication in A&

Percutaneous regional compared with local anaesthesia for facial lacerations: a randomised controlled trial

Objective: Facial lacerations are usually repaired after local infiltration of an anaesthetic agent. Regional nerve blocks of the face offer several theoretical advantages over local infiltration. This study compared the pain of injection and anaesthetic efficacy of percutaneous regional and local anaesthesia for facial lacerations. Study design: Randomised clinical trial. Participants: Convenience sample of emergency department patients with facial lacerations requiring suturing in anatomical areas innervated by a regional nerve (supraorbital, infraorbital, or mental). Interventions: Facial lacerations treated using standard wound care. Lacerations were randomised to local or regional infiltration of lidocaine (lignocaine) 1% with adrenaline (epinephrine) 1:100 000 using a number 27 needle. Outcomes: Pain of injection on 100 mm visual analogue scale (VAS) and need for rescue anaesthetic infiltration before suturing. Data analysis: Group comparisons were with Student's t test and χ(2) test. This study had 80% power to detect a 20 mm difference in pain of injection (two tailed, α = 0.05). Results: 36 patients were randomised to local (18) and regional (18) anaesthesia. Mean (SD) age was 20 (14); 19% were female. Groups were similar in baseline characteristics. Patients in the regional anaesthesia group experienced more pain during infiltration than patients in the local anaesthesia group (42.4 mm v 24.8 mm, mean difference 17.6 mm (95% CI 0.3 to 35.6 mm) and were more likely to require additional infiltration of a local anaesthetic (28% v 0%, (95% CI 6% to 50%)) than patients in the local anaesthetic group. Conclusions: Local infiltration of anaesthetics for facial lacerations is less painful and results in more effective anaesthesia than percutaneous regional infiltration

Phase stability in fMRI time series: Effect of noise regression, off-resonance correction and spatial filtering techniques

Although the majority of fMRI studies exploit magnitude changes only, there is an increasing interest regarding the potential additive information conveyed by the phase signal. This integrated part of the complex number furnished by the MR scanners can also be used for exploring direct detection of neuronal activity and for thermography. Few studies have explicitly addressed the issue of the available signal stability in the context of phase time-series, and therefore we explored the spatial pattern of frequency specific phase fluctuations, and evaluated the effect of physiological noise components (heart beat and respiration) on the phase signal. Three categories of retrospective noise reduction techniques were explored and the temporal signal stability was evaluated in terms of a physiologic noise model, for seven fMRI measurement protocols in eight healthy subjects at 3 T, for segmented CSF, gray and white matter voxels. We confirmed that for most processing methods, an efficient use of the phase information is hampered by the fact that noise from physiological and instrumental sources contributes significantly more to the phase than to the magnitude instability. Noise regression based on the phase evolution of the central k-space point, RETROICOR, or an orthonormalized combination of these were able to reduce their impact, but without bringing phase stability down to levels expected from the magnitude signal. Similar results were obtained after targeted removal of scan-to-scan variations in the bulk magnetic field by the dynamic off-resonance in k-space (DORK) method and by the temporal off-resonance alignment of single-echo time series technique (TOAST). We found that spatial high-pass filtering was necessary, and in vivo a Gaussian filter width of 20 mm was sufficient to suppress physiological noise and bring the phase fluctuations to magnitude levels. Stronger filters brought the fluctuations down to levels dictated by thermal noise contributions, and for 62.5 mm3 voxels the phase stability was as low as 5 mrad (0.27°). In conditions of low SNRo and high temporal sampling rate (short TR); we achieved an upper bound for the phase instabilities at 0.0017 ppm, which is close to the dHb contribution to the GM/WM phase contrast

Isoelectric focusing studies of human pancreatic secretion

Pure bile, pancreatic and duodenal human juices have been analyzed by isoelectric focusing, either at rest or upon stimulation with caerulein. In rats, stimulation has also been performed by secretin. Twenty bands have been resolved and quantified in the pancreatic secretion. By developing zymograms, a number of isozymes have been identified: 6 iso-amylases [pl's 7.2, 7.1 and 6.6 (major) and pl's 7.4, 6.7 and 5.8 (minor)], 3 lipases [pl's 7.0 and 6.8 (major) and 6.4 (minor)], two major alkaline proteases (pl's 9.8 and 8.4) and one major acidic protease (pl 4.3) and one band of RNAase activity (pl 8.6). The stimulation kinetics follow a mechanism according to Palade, indicating uniform response to secretogogues, parallel intracellular transport and parallel discharge of pancreatic exocrine proteins