Assay of aminoglycosides is influenced by tissue homogenization technique

Recovery of neomycin from tissue homogenates was lower when glass/glass homogenizers were used due to the abrasion of glass which will bind to the drug. Glass homogenizers should be avoided for the determination of aminoglycoside levels in tissues.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/42733/1/18_2005_Article_BF01948411.pd