6,054 research outputs found

    Modeling good research practices - overview: a report of the ISPOR-SMDM modeling good research practices task force - 1.

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    Models—mathematical frameworks that facilitate estimation of the consequences of health care decisions—have become essential tools for health technology assessment. Evolution of the methods since the first ISPOR modeling task force reported in 2003 has led to a new task force, jointly convened with the Society for Medical Decision Making, and this series of seven papers presents the updated recommendations for best practices in conceptualizing models; implementing state–transition approaches, discrete event simulations, or dynamic transmission models; dealing with uncertainty; and validating and reporting models transparently. This overview introduces the work of the task force, provides all the recommendations, and discusses some quandaries that require further elucidation. The audience for these papers includes those who build models, stakeholders who utilize their results, and, indeed, anyone concerned with the use of models to support decision making

    Phasing diffuse scattering. Application of the SIR2002 algorithm to the non-crystallographic phase problem

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    A new phasing algorithm has been used to determine the phases of diffuse elastic X-ray scattering from a non-periodic array of gold balls of 50 nm diameter. Two-dimensional real-space images, showing the charge-density distribution of the balls, have been reconstructed at 50 nm resolution from transmission diffraction patterns recorded at 550 eV energy. The reconstructed image fits well with scanning electron microscope (SEM) image of the same sample. The algorithm, which uses only the density modification portion of the SIR2002 program, is compared with the results obtained via the Gerchberg-Saxton-Fienup HIO algorithm. In this way the relationship between density modification in crystallography and the HiO algorithm used in signal and image processing is elucidated.Comment: 7 pages, 12 figure

    Stable Determination of the Electromagnetic Coefficients by Boundary Measurements

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    The goal of this paper is to prove a stable determination of the coefficients for the time-harmonic Maxwell equations, in a Lipschitz domain, by boundary measurements

    Photo-desorption of H2O:CO:NH3 circumstellar ice analogs: Gas-phase enrichment

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    We study the photo-desorption occurring in H2_2O:CO:NH3_3 ice mixtures irradiated with monochromatic (550 and 900 eV) and broad band (250--1250 eV) soft X-rays generated at the National Synchrotron Radiation Research Center (Hsinchu, Taiwan). We detect many masses photo-desorbing, from atomic hydrogen (m/z = 1) to complex species with m/z = 69 (e.g., C3_3H3_3NO, C4_4H5_5O, C4_4H7_7N), supporting the enrichment of the gas phase. At low number of absorbed photons, substrate-mediated exciton-promoted desorption dominates the photo-desorption yield inducing the release of weakly bound (to the surface of the ice) species; as the number of weakly bound species declines, the photo-desorption yield decrease about one order of magnitude, until porosity effects, reducing the surface/volume ratio, produce a further drop of the yield. We derive an upper limit to the CO photo-desorption yield, that in our experiments varies from 1.4 to 0.007 molecule photon−1^{-1} in the range ∼1015−1020\sim 10^{15} - 10^{20}~absorbed photons cm−2^{-2}. We apply these findings to a protoplanetary disk model irradiated by a central T~Tauri star

    Accretion and photodesorption of CO ice as a function of the incident angle of deposition

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    Non-thermal desorption of inter- and circum-stellar ice mantles on dust grains, in particular ultraviolet photon-induced desorption, has gained importance in recent years. These processes may account for the observed gas phase abundances of molecules like CO toward cold interstellar clouds. Ice mantle growth results from gas molecules impinging on the dust from all directions and incidence angles. Nevertheless, the effect of the incident angle for deposition on ice photo-desorption rate has not been studied. This work explores the impact on the accretion and photodesorption rates of the incidence angle of CO gas molecules with the cold surface during deposition of a CO ice layer. Infrared spectroscopy monitored CO ice upon deposition at different angles, ultraviolet-irradiation, and subsequent warm-up. Vacuum-ultraviolet spectroscopy and a Ni-mesh measured the emission of the ultraviolet lamp. Molecules ejected from the ice to the gas during irradiation or warm-up were characterized by a quadrupole mass spectrometer. The photodesorption rate of CO ice deposited at 11 K and different incident angles was rather stable between 0 and 45∘^{\circ}. A maximum in the CO photodesorption rate appeared around 70∘^{\circ}-incidence deposition angle. The same deposition angle leads to the maximum surface area of water ice. Although this study of the surface area could not be performed for CO ice, the similar angle dependence in the photodesorption and the ice surface area suggests that they are closely related. Further evidence for a dependence of CO ice morphology on deposition angle is provided by thermal desorption of CO ice experiments

    Kinetic Theory of Collisionless Self-Gravitating Gases: Post-Newtonian Polytropes

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    In this paper we study the kinetic theory of many-particle astrophysical systems and we present a consistent version of the collisionless Boltzmann equation in the 1PN approximation. We argue that the equation presented by Rezania and Sobouti in A&A 354 1110 (2000) is not the correct expression to describe the evolution of a collisionless self-gravitating gas. One of the reasons that account for the previous statement is that the energy of a free-falling test particle, obeying the 1PN equations of motion for static gravitational fields, is not a static solution of the mentioned equation. The same statement holds for the angular momentum, in the case of spherical systems. We provide the necessary corrections and obtain an equation that is consistent with the corresponding equations of motion and the 1PN conserved quantities. We suggest some potential relevance for the study of high density astrophysical systems and as an application we construct the corrected version of the post-Newtonian polytropes.Comment: 23 pages, 24 figures. Accepted for publication in PR
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