Genetic regulatory pathways of split‐hand/foot malformation

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146859/1/cge13434-sup-0001-EditorialProcess.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/146859/2/cge13434_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/146859/3/cge13434.pd

Relativistic electrons from sparks in the laboratory

Discharge experiments were carried out at the Eindhoven University of Technology in 2013. The experimental setup was designed to search for electrons produced in meter-scale sparks using a 1 MV Marx generator. Negative voltage was applied to the high voltage (HV) electrode. Five thin (1 mm) plastic detectors (5 $\rm cm^2$ each) were distributed in various configurations close to the spark gap. Earlier studies have shown (for HV negative) that X-rays are produced when a cloud of streamers is developed 30-60 cm from the negative electrode. This indicates that the electrons producing the X-rays are also accelerated at this location, that could be in the strong electric field from counterstreamers of opposite polarity. Comparing our measurements with modeling results, we find that $\sim$300 keV electrons produced about 30-60 cm from the negative electrode are the most likely source of our measurements. A statistical analysis of expected detection of photon bursts by these fiber detectors indicates that only 20%-45% of the detected bursts could be from soft ($\sim$10 keV) photons, which further supports that the majority of detected bursts are produced by relativistic electrons

Measuring Sizes of Marginally Resolved Young Globular Clusters with HST

We present a method to derive sizes of marginally resolved star clusters from HST/WFPC2 observations by fitting King models to observations. We describe results on both simulated images and on observations of young compact clusters in NGC 3597 and NGC 1275. From the simulations, we find that we can measure King model concentrations (c) to an accuracy of about a factor of two for all combinations of c and King radius (r_0) of interest if the data have high S/N (>~ 500 for the integrated brightness). If the concentration is accurately measured, we can measure the King radius accurately. For lower S/N, marginally resolved King profiles suffer from a degeneracy; different values of the concentration give different r_0 but have comparable reduced chi-squared values. In this case, neither the core radius nor the concentration can be constrained individually, but the half-light radius can be recovered accurately. In NGC 3597, we can only differentiate between concentrations for the very brightest clusters; these suggest a concentration of ~ 2. Assuming a concentration of 2 for the rest of the objects, we find an average King radius for the clusters in NGC 3597 of 0.7 pc, while the clusters in NGC 1275 have an average radius of 1.1 pc. These are similar to the average core radii for Galactic globular clusters, 0.92 pc. We find average half-light radii of 5.4 pc and 6.2 pc for the young clusters in NGC 3597 and NGC 1275, respectively, while the average half-light radii of Galactic globulars is 3.4 pc. The spread in the derived radial parameters in each cluster system is comparable to that observed in the Galactic globular cluster system.Comment: 38 pages, 19 figures, accepted for publication in PAS

On the Nucleon Distribution Amplitude: The Heterotic Solution

We present a new nucleon distribution amplitude which amalgamates features of the Chernyak-Ogloblin-Zhitnitsky model with those of the Gari-Stefanis model. This "heterotic" solution provides the possibility to have asymptotically a small ratio \hbox{$\vert G_{M}^{n}\vert/G_{M}^{p}\le 0.1$}, while fulfilling most of the sum-rule requirements up to the third order. Using this nucleon distribution amplitude we calculate the electromagnetic and weak nucleon form factors, the transition form factor $\gamma p \Delta^{+}$ and the decay widths of the charmonium levels $^3S_{1}$, $^3P_{1}$, and $^3P_{2}$ into $p\bar p$. The agreement with the available data is remarkable in all cases.Comment: 15 pages, RUB-TPII-21/92 Preprin

Approach to Perturbative Results in the N-Delta Transition

We show that constraints from perturbative QCD calculations play a role in the nucleon to Delta(1232) electromagnetic transition even at moderate momentum transfer scales. The pQCD constraints, tied to real photoproduction data and unseparated resonance response functions, lead to explicit forms for the helicity amplitudes wherein the E2/M1 ratio remains small at moderately large momentum transfer.Comment: 4 pages, 2 figures, ReVTe

Masses of the 70- Baryons in Large Nc QCD

The masses of the negative parity 70-plet baryons are analyzed in large N_c QCD to order 1/N_c and to first order in SU(3) symmetry breaking. The existing experimental data are well reproduced and twenty new observables are predicted. The leading order SU(6) spin-flavor symmetry breaking is small and, as it occurs in the quark model, the subleading in 1/N_c hyperfine interaction is the dominant source of the breaking. It is found that the Lambda(1405) and Lambda(1520) are well described as three-quark states and spin-orbit partners. New relations between splittings in different SU(3) multiplets are found.Comment: 11 pages; references were added and a couple of improvements to the text were mad

On Effect of Equilibrium Fluctuations on Superfluid Density in Layered Superconductors

We calculate suppression of inter- and intralayer superconducting currents due to equilibrium phase fluctuations and find that, in contrast to a recent prediction, the effect of thermal fluctuations cannot account for linear temperature dependence of the superfluid density in high-Tc superconductors at low temperatures. Quantum fluctuations are found to dominate over thermal fluctuations at low temperatures due to hardening of their spectrum caused by the Josephson plasma resonance. Near Tc sizeable thermal fluctuations are found to suppress the critical current in the stack direction stronger, than in the direction along the layers. Fluctuations of quasiparticle branch imbalance make the spectral density of voltage fluctuations at small frequencies non zero, in contrast to what may be expected from a naive interpretation of Nyquist formula.Comment: 5 pages, LaTeX, RevTeX, Submitted to PR