21 research outputs found
SIDA-Sport, IdentitĂ ed Adolescenza: Verso la costruzione di un nuovo protocollo di valutazione.
La psicologia dello sport ha abbracciato lo studio dell'identità atletica negli anni Novanta. L’obiettivo della nostra ricerca, dopo un’attenta revisione [Filippini et al,2023]1, è quello di creare un nuovo protocollo, che possa integrare una parte quantitativa ad una parte qualitativa, dando vita, così, ad una nuova batteria di test che vada ad individuare l’efficacia dello sport nella costruzione dell’identità nella fase adolescenzial
Giustizia, etica e politica nella cittĂ
Il volume raccoglie le lettere, i messaggi, gli articoli, gli interventi, le omelie, i colloqui del cardinal Carlo Maria Martini che hanno avuto per oggetto la cittĂ , i temi della convivenza sociale e della formazione politica, i problemi del lavoro, dell'assistenza, del'amministrazione, della corruzione e della giustizia, interpretati sempre alla luce dell'etica comunitaria, con le sue problematiche trasformazioni
Non-invasive evaluation of autonomic tone changes during isometric exercise innormal subjects and in patients with coronary artery disease
In order to evaluate the clinical implications of QT/QS2 ratio during manoeuvres
of sympathetic stimulation we studied the effects of handgrip (75% of maximal
voluntary contraction) in 18 middle-aged normal subjects and in 16 patients with
previous myocardial infarction. We also evaluated the effects of propranolol (0.1
mg/kg i.v.) in all normal subjects and in 10 of the 16 patients with coronary
artery disease. At rest the two groups had similar heart rate, blood pressure,
QT, QS2 and QT/QS2 ratio values. A significant increase in heart rate and
systolic blood pressure was recorded during handgrip both in normal subjects and
in patients with coronary artery disease; QT/QS2 significantly increased in
normal subjects but did not show significant variations in patients with coronary
artery disease, with significant differences between the two groups at peak
exercise. Handgrip-induced QT/QS2 changes showed a marked variability both in
normal and diseased subjects. After propranolol, QT/QS2 showed no significant
difference at peak exercise in the two groups. The variability of ratio changes
was nullified by the administration of the drug. These findings suggest that
handgrip-induced QT/QS2 changes might be an expression of beta-adrenergic
discharge. The clinical value of handgrip-induced QT/QS2 changes in detecting
patients with coronary artery disease is limited by the variability of the
response of the ratio observed in the two groups
Relazione tra la durata della sistole elettrica e la fibrillazione ventricolare primaria in pazienti anziani in corso di infarto acuto del miocardio
Relationship between QT interval duration and exercise-induced ventricular arrhythmias
This study was performed to determine if QT prolongation before and during early
exercise is related to the occurrence of exercise-induced ventricular arrhythmias
(EIVA). EIVA occurred in 47 of 142 patients with angiographic evidence of
coronary artery disease (CAD); no EIVA occurred among the 22 patients without CAD
(OV). Resting QTc and QT intervals during early exercise were similar in patients
without EIVA, irrespective of the presence or absence of CAD; however resting QTc
was significantly longer in CAD patients who showed EIVA (443 +/- 40 ms; P less
than 0.01) than in CAD patients without EIVA (424 +/- 37 ms) and in OV patients
(421 +/- 32 ms). During early exercise, the QT interval remained significantly
longer in patients with than in those without EIVA. There was a trend toward
increasing resting QTc in patients who exhibited EIVA more severe than grade 3.
When resting QTc was longer than 440 ms, subsequent EIVA were correctly predicted
in CAD patients with a sensitivity of 43%, a specificity of 72% and a predictive
accuracy of 63%. Thus, a trend toward longer resting QTc values exists in CAD
patients who develop EIVA; however, a long resting QTc (greater than 440 ms)
appears to be only a weak predictor of subsequent EIVA
Effects of aging and beta-adrenergic-blockade on standing-induced QT/QS2 changes
In order to evaluate whether the changes in the electrical
systole/electromechanical systole ratio (QT/QS2) may reflect the effects of
beta-adrenergic stimulation on the heart, we studied the variations of this ratio
induced by active standing. We studied 45 healthy volunteers aged 15 to 82 years,
subdivided into three groups; Group 1 (mean age 22 +/- 4 years), Group 2 (mean
age 44 +/- 6 years), and Group 3 (mean age 74 +/- 6 years). Fifteen subjects
repeated the test after propranolol administration (0.1 mg/kg iv). Resting QT/QS2
ratio increased slightly, but not significantly, with age. Upright position
significantly increased QT/QS2 ratio in all groups. Changes in heart rate (r =
-.43), electromechanical systole (r = .55) and QT/QS2 were significantly
correlated with age. Propranolol prevented the increase in QT/QS2 ratio induced
by active standing. Therefore, QT/QS2 changes induced by standing are correlated
with age and are inhibited or reduced by beta-blockade. QT/QS2 changes can be
used to monitor adrenergic activity, even if their value is limited by the
overlapping responses of the individual cases
Efficacy of diltiazem in elderly patients with stable effort angina
The antianginal effects of 360 mg/day of diltiazem were evaluated, using
intrapatient comparisons, in a double/blind, randomized, placebo/controlled trial
in 24 young patients (50 +/- 7 years) and in 16 elderly patients (67 +/- 3 years)
with stable effort angina. All patients had angiographic documentation of
significant coronary artery disease. An open-labelled, randomized, crossover
design was employed. For 1 week prior to beginning the study, the patient was on
no medication except sublingual nitrates. The study consisted of an initial
2-week single-blind placebo run-in period followed by a 4-week randomized
double-blind crossover between diltiazem, 120 mg t.i.d., and placebo. A diary of
chest pain and nitroglycerin usage was kept during this period and run-in.
Exercise tests were carried out during the run-in period (2 tests) and at the end
of the 4-week treatment. After diltiazem 12 of the 24 young patients stopped the
exercise test because of angina. A similar number (9/16) of elderly patients
stopped the exercise test because of angina. During diltiazem treatment, weekly
angina frequency was significantly reduced in the young patients (1.25 +/- 0.67
vs 3.87 +/- 1.19-run-in, 4.08 +/- 1.24-placebo; p less than 0.01) and in the
elderly patients (0.87 +/- 0.71 vs 4.06 +/- 1.48-run-in, 4.12 +/- 1.5-placebo; p
less than 0.01). Weekly TNT consumption significantly decreased in both groups of
patients