30 research outputs found
Les infections aigues des voies respiratoires superieures
SCOPUS: re.jinfo:eu-repo/semantics/publishe
An unusual localisation of Kaposi's sarcoma: The external auditory canal
The epidemic form of Kaposi's sarcoma is associated with human immunodeficiency virus infection. Cutaneous and mucosal manifestations are frequently reported in the ENT sphere, mostly involving the oral cavity. The external and middle ear are only rarely concerned with only one case of a mastoid lesion within extension to the external auditory canal (EAC) being reported to this day. The present article describes the first case of involvement of the EAC with extension to adjacent structures. This patient presented other Kaposi lesions and had been treated by systemic hormonal therapy. Thereafter local injection of a cytotoxic agent was given without effect. Finally, radiotherapy resulted in a 50% regression of the tumour mass. The epidemiologic factors and therapeutic modalities with their results are described.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Otogenic thrombosis of the lateral sinus :Report of a case in a child
A case of thrombosis of the lateral sinus complicating the mastoiditis in a five year old boy is presented. This intracranial complication of suppurative otitis media which has become rare since the use of antibiotics, still raises diagnostic and therapeutic problems. The various clinical and paraclinical elements of this rare pathology, its diagnosis and treatment are reviewed.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Mucins and secreted factors
Mucins and secreted factors. Mucin is a large glycoprotein (M up to 4-6.106) with a high content of serine, threonine, and proline residues and numerous O-linked saccharides, often occurring in clusters on the polypeptide. Nine mucin genes exist in humans that encode an apomucin highly modified by O-glycans in forming epithelial mucins. These are variably expressed by epithelial cells of the gastrointestinal, tracheobronchial and reproductive tracts. They may be found either membrane-associated or secreted. As might be imagined from their ubiquitous and complex nature, the biological roles of glycans are quite varied. Protection against infection is an important biological role. Alterations in their carbohydrate moiety have been reported in airway and salivary mucins secreted by patients suffering of cystic fibrosis (CF). Moreover, changes in expression of glycans are also often reported in the setting of transformation and progression to malignancy. Due to the key roles played by glycans of glycoconjugates in both physiological and pathological events, glycobiology and carbohydrate chemistry have become of increasing importance in modern biotechnology.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Tonsillar lymphoma and AIDS
A case of a patient presenting unilateral tonsillar enlargement, whereby non-Hodgkin lymphoma (NHL) and AIDS were diagnosed, is presented. The clinical and pathological aspects of this pathology, its pathogenicity and treatment are reviewed.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Lobular capillary haemangioma of the nasal cavity during pregnancy
Objective: We report a pregnant patient with a rapidly growing mass within the nasal cavity' which required pre-operative super-selective embolisation and subsequent removal under general anaesthesia after childbirth. We also discuss the clinical' radiological and histological characteristics of lobular capillary haemangioma' and its treatment.Method: Case report and literature review.Results: Lobular capillary haemangioma is a benign lesion originating in the vascular tissue of skin' mucosa' muscles' glands and bone. These lesions grow rapidly. Nasal localisation is rare. Microtrauma and pregnancy are the most commonly proposed aetiological factors. Reported incidence during pregnancy ranges from less than 2 per cent to approximately 5 per cent. The management of a pregnant woman with such a lesion may be complex' and depends on the severity of symptoms and the status of the pregnancy. Complete surgical excision' with or without pre-operative embolisation' is the treatment of choice.Conclusion: This uncommon lesion should be considered in any pregnant patient with a mass in the mouth or nasal cavity. 漏 JLO (1984) Limited 2011.SCOPUS: re.jinfo:eu-repo/semantics/publishe
Laryngeal aspergillosis in an acquired immunodeficiency syndrome patient
SCOPUS: ar.jinfo:eu-repo/semantics/publishe