INCURSION IN A CONTRAST SENSITIVITY CHANGES RELATED TO NON-PROLIFERATIVE DIABETIC RETINOPATHY

The paper followed the possible relationship between variability of contrast sensitivity tests and glycemic level in non-proliferative diabetic retinopathy using Spectral Domain OCT (SD-OCT), during daytime, related to changes of normal retinal layers. For this task, we investigated eyes with non-proliferative diabetic retinopathy (mild, medium and severe forms) by assessing the contrast sensitivity through Pelli Robson Test and micro-perimeter and retinal thickness using SD OCT. The images were analyzed using two software: ImageJ and Maviiss 1.5 (Mtf-bAsed Visible and Infrared Imaging System Simulation). The diabetic group was matched by similar control group (for age and sex) of healthy eyes. Our results showed a correlation between the retinal thickness during daytime, contrast sensitivity loss and glycemic variations that can be used as further investigation tool

TFOS DEWS II Tear Film Report

The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears and how these change in DED. Clinically, DED is characterized by loss of tear volume, more rapid breakup of the tear film and increased evaporation of tears from the ocular surface. The tear film is composed of many substances including lipids, proteins, mucins and electrolytes. All of these contribute to the integrity of the tear film but exactly how they interact is still an area of active research. Tear film osmolarity increases in DED. Changes to other components such as proteins and mucins can be used as biomarkers for DED. The Subcommittee recommended areas for future research to advance our understanding of the tear film and how this changes with DED. The final report was written after review by all Subcommittee members and the entire TFOS DEWS II membership. (C) 2017 Elsevier Inc. All rights reserved.Peer reviewe