11 research outputs found

    Accuracy versus precision in boosted top tagging with the ATLAS detector

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    Abstract The identification of top quark decays where the top quark has a large momentum transverse to the beam axis, known as top tagging, is a crucial component in many measurements of Standard Model processes and searches for beyond the Standard Model physics at the Large Hadron Collider. Machine learning techniques have improved the performance of top tagging algorithms, but the size of the systematic uncertainties for all proposed algorithms has not been systematically studied. This paper presents the performance of several machine learning based top tagging algorithms on a dataset constructed from simulated proton-proton collision events measured with the ATLAS detector at √ s = 13 TeV. The systematic uncertainties associated with these algorithms are estimated through an approximate procedure that is not meant to be used in a physics analysis, but is appropriate for the level of precision required for this study. The most performant algorithms are found to have the largest uncertainties, motivating the development of methods to reduce these uncertainties without compromising performance. To enable such efforts in the wider scientific community, the datasets used in this paper are made publicly available.</jats:p

    Whole blood assay to access T cell-immune responses to Mycobacterium tuberculosis antigens in healthy Brazilian individuals

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    The production of interferon gamma (IFNgamma) guarantees effective T cell-mediated immunity against Mycobacterium tuberculosis infection. In the present study, we simply compare the in vitro immune responses to Mycobacterium antigens in terms of IFNg production in a total of 10 healthy Brazilian volunteers. Whole blood and mononuclear cells were cultivated in parallel with PPD, Ag85B, and M. bovis hsp65, and five-days supernatants were harvested for cytokine detection by ELISA. The inter-assay result was that the overall profile of agreement in response to antigens was highly correlated (r² = 0.9266; p = 0.0102). Potential analysis is in current progress to dictate the usefulness of this method to access the immune responses also in tuberculosis patients and its contacts

    Long-term outcomes of the global tuberculosis and COVID-19 co-infection cohort.

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    Longitudinal cohort data of patients with tuberculosis (TB) and coronavirus disease 2019 (COVID-19) are lacking. In our global study, we describe long-term outcomes of patients affected by TB and COVID-19. We collected data from 174 centres in 31 countries on all patients affected by COVID-19 and TB between 1 March 2020 and 30 September 2022. Patients were followed-up until cure, death or end of cohort time. All patients had TB and COVID-19; for analysis purposes, deaths were attributed to TB, COVID-19 or both. Survival analysis was performed using Cox proportional risk-regression models, and the log-rank test was used to compare survival and mortality attributed to TB, COVID-19 or both. Overall, 788 patients with COVID-19 and TB (active or sequelae) were recruited from 31 countries, and 10.8% (n=85) died during the observation period. Survival was significantly lower among patients whose death was attributed to TB and COVID-19 versus those dying because of either TB or COVID-19 alone (p&lt;0.001). Significant adjusted risk factors for TB mortality were higher age (hazard ratio (HR) 1.05, 95% CI 1.03-1.07), HIV infection (HR 2.29, 95% CI 1.02-5.16) and invasive ventilation (HR 4.28, 95% CI 2.34-7.83). For COVID-19 mortality, the adjusted risks were higher age (HR 1.03, 95% CI 1.02-1.04), male sex (HR 2.21, 95% CI 1.24-3.91), oxygen requirement (HR 7.93, 95% CI 3.44-18.26) and invasive ventilation (HR 2.19, 95% CI 1.36-3.53). In our global cohort, death was the outcome in &gt;10% of patients with TB and COVID-19. A range of demographic and clinical predictors are associated with adverse outcomes

    Bactérias gram-positivas problemas: resistência do estafilococo, do enterococo e do pneumococo aos antimicrobianos

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    Measurement of the t t ¯ cross section and its ratio to the Z production cross section using pp collisions at s = 13.6 TeV with the ATLAS detector

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    Pursuit of paired dijet resonances in the Run 2 dataset with ATLAS

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    New particles with large masses that decay into hadronically interacting particles are predicted by many models of physics beyond the Standard Model. A search for a massive resonance that decays into pairs of dijet resonances is performed using..

    Improving topological cluster reconstruction using calorimeter cell timing in ATLAS

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    Fast b-tagging at the high-level trigger of the ATLAS experiment in LHC Run 3

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    The ATLAS experiment relies on real-time hadronic jet reconstruction and b-tagging to record fully hadronic events containing b-jets. These algorithms require track reconstruction, which is computationally expensive and could overwhelm the high-level-trigger farm, even at the reduced event rate that passes the ATLAS first stage hardware-based trigger. In LHC Run 3, ATLAS has mitigated these computational demands by introducing a fast neural-network-based b-tagger, which acts as a low-precision filter using input from hadronic jets and tracks. It runs after a hardware trigger and before the remaining high-level-trigger reconstruction. This design relies on the negligible cost of neural-network inference as compared to track reconstruction, and the cost reduction from limiting tracking to specific regions of the detector. In the case of Standard Model HH → bb̅bb̅, a key signature relying on b-jet triggers, the filter lowers the input rate to the remaining high-level trigger by a factor of five at the small cost of reducing the overall signal efficiency by roughly 2%

    Search for the Zγ decay mode of new high-mass resonances in pp collisions at s = 13 TeV with the ATLAS detector

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    This letter presents a search for narrow, high-mass resonances in the Zγ final state with the Z boson decaying into a pair of electrons or muons. The TeV pp collision data were recorded by the ATLAS detector at the CERN Large Hadron Collider and have an integrated luminosity of 140 fb−1. The data are found to be in agreement with the Standard Model background expectation. Upper limits are set on the resonance production cross section times the decay branching ratio into Zγ. For spin-0 resonances produced via gluon–gluon fusion, the observed limits at 95% confidence level vary between 65.5 fb and 0.6 fb, while for spin-2 resonances produced via gluon–gluon fusion (or quark–antiquark initial states) limits vary between 77.4 (76.1) fb and 0.6 (0.5) fb, for the mass range from 220 GeV to 3400 GeV
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