Axial Spondyloarthritis: Reshape the Future—From the “2022 GISEA International Symposium”

The term “axial spondyloarthritis” (axSpA) refers to a group of chronic rheumatic diseases that predominantly involve the axial skeleton and consist of ankylosing spondylitis, reactive arthritis, arthritis/spondylitis associated with psoriasis (PsA) and arthritis/spondylitis associated with inflammatory bowel diseases (IBD). Moreover, pain is an important and common symptom of axSpA. It may progress to chronic pain, a more complicated bio-psychosocial phenomena, leading to a significant worsening of quality of life. The development of the axSpA inflammatory process is grounded in the complex interaction between genetic (such as HLA B27), epigenetic, and environmental factors associated with a dysregulated immune response. Considering the pivotal contribution of IL-23 and IL-17 in axSpA inflammation, the inhibition of these cytokines has been evaluated as a potential therapeutic strategy. With this context, here we discuss the main pathogenetic mechanisms, therapeutic approaches and the role of pain in axSpA from the 2022 International GISEA/OEG Symposium

Vita di Mecenate

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Rime piaceuoli / di Cesare Caporali, del Mauro, et d'altri auttori.

Accresciute in questa quinta impressione di molte rime graui [et] burlesche del signor Toquato Tasso, del signor Anibal Caro, [et] di diuersi nobilissimi ingegni.Existe otro estado donde la fecha no precede al nombre de imp. en port.Marca tip. en port. (Edit 16, U10).Sign.: A-P12, Q6.Il. xil.Capitulares grab. xil

Rime piaceuoli

Marca tip. en portFecha precede a nombre de imp. en portSign.: A-P\p12\s, Q\p6\

Nickel-Decorated Black Phosphorus for Room Temperature NO 2 detection

none8noneMatteo Valt; Maria Caporali; Barbara Fabbri; Andrea Gaiardo; Cesare Malagù; Manuel Serrano-Ruiz; Maurizio Peruzzini; Vincenzo GuidiValt, Matteo; Caporali, Maria; Fabbri, Barbara; Gaiardo, Andrea; Malagù, Cesare; Serrano-Ruiz, Manuel; Peruzzini, Maurizio; Guidi, Vincenz

Nickel-decorated black phosphorus for sub-ppm NO2 detection at room temperature

We study the electrical characterization at room temperature (RT) of black phosphorus nanoflakes decorated with nickel nanoparticles (Ni/bP). The latter has been exposed to different concentrations of NO2 at RT in a dry air environment highlighting fast and stable response over the time. This latter characteristic is particularly relevant since environmental instability of exfoliated BP has been an issue so far, under ambient conditions few-layer BP degrades completely in less than a week, preventing its applications in several fields

Elucidating the Ambient Stability and Gas Sensing Mechanism of Nickel-Decorated Phosphorene for {NO}2 Detection: A First-Principles Study

In the field of layered two-dimensional functional materials, black phosphorus has attracted considerable attention in many applications due to its outstanding electrical properties. It has experimentally shown superior chemical sensing performance for the room temperature detection of NO2, highlighting high sensitivity at a ppb level. Unfortunately, pristine black phosphorus demonstrated an unstable functionality due to the fast degradation of the material when exposed to the ambient atmosphere. In the present work, a deepened investigation by density functional theory was carried out to study how nickel decoration of phosphorene can improve the stability of the material. Further, an insight into the sensing mechanism of nickel loaded phosphorene toward NO2 was given and compared to pristine phosphorene. This first-principles study proved that, by introducing nickel adatoms, the band gap of the material decreases and the positions of the conduction band minimum and the valence band maximum move toward each other, resulting in a drop in the conduction band minimum under the redox potential of O2/O2−, which may result in a more stable material. Studying the adsorption of O2 molecules on pristine phosphorene, we also proved that all oxygen molecules coming from the surrounding atmosphere react with phosphorus atoms in the layer, resulting in the oxidation of the material forming oxidized phosphorus species (POx). Instead, by introducing nickel adatoms, part of the oxygen from the surrounding atmosphere reacts with nickel atoms, resulting in a decrease of the oxidation rate of the material and in subsequent long-term stability of the device. Finally, possible reaction paths for the detection of NO2 are given by charge transfer analyses, occurring at the surface during the adsorption of oxygen molecules and the interaction with the target gas

Wide Angle Camera for Bepi Colombo

Wide Angle Camera for Bepi Colomb

Air Stable Nickel-Decorated Black Phosphorus and Its Room-Temperature Chemiresistive Gas Sensor Capabilities

In the rapidly emerging field of layered two-dimensional functional materials, black phosphorus, the P-counterpart of graphene, is a potential candidate for various applications, e.g., nanoscale optoelectronics, rechargeable ion batteries, electrocatalysts, thermoelectrics, solar cells, and sensors. Black phosphorus has shown superior chemical sensing performance; in particular, it is selective for the detection of NO2, an environmental toxic gas, for which black phosphorus has highlighted high sensitivity at a ppb level. In this work, by applying a multiscale characterization approach, we demonstrated a stability and functionality improvement of nickel-decorated black phosphorus films for gas sensing prepared by a simple, reproducible, and affordable deposition technique. Furthermore, we studied the electrical behavior of these films once implemented as functional layers in gas sensors by exposing them to different gaseous compounds and under different relative humidity conditions. Finally, the influence on sensing performance of nickel nanoparticle dimensions and concentration correlated to the decoration technique and film thickness was investigated

A Wide Angle Camera for Bepi Colombo

Proceedings of a workshop held at The Field Museum, 4-5 October, 2001, Chicago, I