Multi-hop relaying using energy harvesting

In this letter, the performance of multi-hop relaying using energy harvesting is evaluated. Both amplify-and-forward and decode-and-forward relaying protocols are considered. The evaluation is conducted for time-switching energy harvesting as well as power-splitting energy harvesting. The largest number of hops given an initial amount of energy from the source node is calculated. Numerical results show that, in order to extend the network coverage using multi-hop relaying, time-switching is a better option than power splitting and in some cases, decode-and-forward also supports more hops than amplify-and-forward

Electrochemical Performances of Electroactive Nano-Layered Organic-Inorganic Perovskite Containing Trivalent Iron Ion and its Use for a DNA Biosensor Preparation

A steady nano organic-inorganic perovskite hybrid with [H23-AMP]3/2Fe(CN)6 (3-AMP = 3-methylaminopyridine) was prepared in the air. The structure is an unusual layered organic-inorganic type. The resulting hybrid enveloped in paraffin to prepare [H23-AMP]3/2Fe(CN)6 paste electrode (HPE) shows good electrochemical activity and a couple of oxidation and reduction peaks with potential of cyclic voltammometry (CV) at around 440 mV and 30 mV. Compared with that on CPE, oxidation potential of Fe(CN)63− on HPE shifts negatively 259.7 mV and that of reduction shifts positively 338.7 mV, which exhibits that [H23-AMP]3/2Fe(CN)6 can accelerate the electron-transfer to improve the electrochemical reaction reversibility. Such characteristics of [H23-AMP]3/2Fe(CN)6 have been employed to prepare the DNA biosensor. The single-strand DNA (ssDNA) and double-strand DNA (dsDNA) immobilized on HPE, respectively, can improve the square wave voltammometry (SWV) current and SWV potential shifts positively. The effect of pH was evaluated. And there is hybridization peak on SWV curve using HPE immobilized ssDNA in the complementary ssDNA solution. And HPE immobilized ssDNA can be utilized to monitor the DNA hybridization and detect complementary ssDNA, covering range from 3.24 × 10−7 to 6.72 × 10−5 g/mL with detection limit of 1.57 × 10−7 g/mL. The DNA biosensor exhibits a good stability and reproducibility

Multi-Hop Relaying Using Energy Harvesting

In this letter, the performance of multi-hop relaying using energy harvesting is evaluated. Both amplify-and-forward and decode-and-forward relaying protocols are considered. The evaluation is conducted for time-switching energy harvesting as well as power-splitting energy harvesting. The largest number of hops given an initial amount of energy from the source node is calculated. Numerical results show that, in order to extend the network coverage using multi-hop relaying, time-switching is a better option than power splitting and in some cases, decode-and-forward also supports more hops than amplify-and-forward

Transcriptome Profile Analysis on Ovarian Tissues of Autotetraploid Fish and Diploid Red Crucian Carp

Polyploidization can significantly alter the size of animal gametes. Autotetraploid fish (RRRR, 4nRR = 200) (4nRR) possessing four sets of chromosomes were derived from whole-genome duplication in red crucian carp (RR, 2n = 100) (RCC). The diploid eggs of the 4nRR fish were significantly larger than the eggs of RCC. To explore the differences between the ovaries of these two ploidies of fishes at the molecular level, we compared the ovary transcriptome profiles of 4nRR fish and RCC and identified differentially expressed genes (DEGs). A total of 19,015 unigenes were differentially expressed between 4nRR fish and RCC, including 12,591 upregulated and 6,424 downregulated unigenes in 4nRR fish. Functional analyses revealed that eight genes (CDKL1, AHCY, ARHGEF3, TGFβ, WNT11, CYP27A, GDF7, and CKB) were involved in the regulation of cell proliferation, cell division, gene transcription, ovary development and energy metabolism, suggesting that these eight genes were related to egg size in 4nRR fish and RCC. We validated the expression levels of these eight DEGs in 4nRR fish and RCC using quantitative PCR. The study results provided insights into the regulatory mechanisms underlying the differences in crucian carp egg sizes

Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease

BACKGROUND: Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based treatment of low-density lipoprotein (LDL) cholesterol levels. The inhibition of cholesteryl ester transfer protein (CETP) by anacetrapib reduces LDL cholesterol levels and increases high-density lipoprotein (HDL) cholesterol levels. However, trials of other CETP inhibitors have shown neutral or adverse effects on cardiovascular outcomes. METHODS: We conducted a randomized, double-blind, placebo-controlled trial involving 30,449 adults with atherosclerotic vascular disease who were receiving intensive atorvastatin therapy and who had a mean LDL cholesterol level of 61 mg per deciliter (1.58 mmol per liter), a mean non-HDL cholesterol level of 92 mg per deciliter (2.38 mmol per liter), and a mean HDL cholesterol level of 40 mg per deciliter (1.03 mmol per liter). The patients were assigned to receive either 100 mg of anacetrapib once daily (15,225 patients) or matching placebo (15,224 patients). The primary outcome was the first major coronary event, a composite of coronary death, myocardial infarction, or coronary revascularization. RESULTS: During the median follow-up period of 4.1 years, the primary outcome occurred in significantly fewer patients in the anacetrapib group than in the placebo group (1640 of 15,225 patients [10.8%] vs. 1803 of 15,224 patients [11.8%]; rate ratio, 0.91; 95% confidence interval, 0.85 to 0.97; P=0.004). The relative difference in risk was similar across multiple prespecified subgroups. At the trial midpoint, the mean level of HDL cholesterol was higher by 43 mg per deciliter (1.12 mmol per liter) in the anacetrapib group than in the placebo group (a relative difference of 104%), and the mean level of non-HDL cholesterol was lower by 17 mg per deciliter (0.44 mmol per liter), a relative difference of -18%. There were no significant between-group differences in the risk of death, cancer, or other serious adverse events. CONCLUSIONS: Among patients with atherosclerotic vascular disease who were receiving intensive statin therapy, the use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo. (Funded by Merck and others; Current Controlled Trials number, ISRCTN48678192 ; ClinicalTrials.gov number, NCT01252953 ; and EudraCT number, 2010-023467-18 .)

Adaptive and Efficient Mixture-Based Representation for Range Data

Modern range sensors generate millions of data points per second, making it difficult to utilize all incoming data effectively in real time for devices with limited computational resources. The Gaussian mixture model (GMM) is a convenient and essential tool commonly used in many research domains. In this paper, an environment representation approach based on the hierarchical GMM structure is proposed, which can be utilized to model environments with weighted Gaussians. The hierarchical structure accelerates training by recursively segmenting local environments into smaller clusters. By adopting the information-theoretic distance and shape of probabilistic distributions, weighted Gaussians can be dynamically allocated to local environments in an arbitrary scale, leading to a full adaptivity in the number of Gaussians. Evaluations are carried out in terms of time efficiency, reconstruction, and fidelity using datasets collected from different sensors. The results demonstrate that the proposed approach is superior with respect to time efficiency while maintaining the high fidelity as compared to other state-of-the-art approaches

The Effect of Misdetection Probability on the Performance of Cooperative-Relaying-Based Cognitive Radio Systems

Cognitive radio (CR) is a promising solution to address the more and more congested radio spectrum. Cooperative relaying can provide a better transmission performance for the secondary user (SU), while the performance of the primary user (PU, also named licensed user) should be preferentially protected especially when there is misdetection probability. In this paper, in order to keep the PU away from outage caused by the interference from the SU under a certain signal-to-noise ratio (SNR), the maximum SNR for the SU can be derived by using the rate decaying factor (RDF). Then, based on the maximum channel gain and the maximum SNR, the outage probability is analyzed using decode-and-forward (DF) relaying and amplify-and-forward (AF) relaying schemes. Numerical results show that the outage probability decreases when the power allocation factor increases for DF strategy, while the outage probability has error floor when the power allocation factor increases for AF strategy. And the relaying scheme based on the maximum channel gain outperforms that based on the maximum SNR when the power allocation factor and detection probability are small, while the relaying scheme based on the maximum SNR outperforms that based on the maximum channel gain when the power allocation factor is large. What is more, AF relaying has better outage performance in the practical implementation