67 research outputs found
Prospective associations between a priori dietary patterns adherence and kidney function in an elderly Mediterranean population at high cardiovascular risk
Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. This work was supported by the official Spanish Institutions for funding scientific biomedical research, CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN) and Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigacion para la Salud (FIS), which is co-funded by the European Regional Development Fund (six coordinated FIS projects leaded by JS-S and JVi, including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, PI19/01332, PI20/01802, PI20/00138, PI20/01532, PI20/00456, PI20/00339, PI20/00557, PI20/00886, PI20/01158); the Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-Plus grant to JS-S; the European Research Council (Advanced Research Grant 2014-2019; agreement #340918) granted to MAMG.; the Recercaixa (number 2013ACUP00194) grant to JS-S; grants from the Consejeria de Salud de la Junta de Andalucia (PI0458/2013, PS0358/2016, PI0137/2018); the PROMETEO/2017/017 and the PROMETEO 21/2021 grant from the Generalitat Valenciana; the SEMERGEN grant; the Boosting young talent call grant program for the development of IISPV research projects 2019-2021 (Ref.: 2019/IISPV/03 grant to AD-L); the Societat Catalana d'Endocrinologia i Nutricio (SCEN) Clinical-Research Grant 2019 (IPs: JS-S and AD-L). Collaborative Nutrition and/or Obesity Project for Young Researchers 2019 supported by CIBEROBN entitled: Lifestyle Interventions and Chronic Kidney Disease: Inflammation, Oxidative Stress and Metabolomic Profile (LIKIDI study) grant to AD-L. Jordi Salas-Salvado, gratefully acknowledges the financial support by ICREA under the ICREA Academia programme. M.R.-G., is supported by the Ministry of Education of Spain (FPU17/06488). None of the funding sources took part in the design, collection, analysis, interpretation of the data, or writing the report, or in the decision to submit the manuscript for publication.Purpose To assess the association between three different a priori dietary patterns adherence (17-item energy reduced-
Mediterranean Diet (MedDiet), Trichopoulou-MedDiet and Dietary Approach to Stop Hypertension (DASH)), as well as
the Protein Diet Score and kidney function decline after one year of follow-up in elderly individuals with overweight/obesity
and metabolic syndrome (MetS).
Methods We prospectively analyzed 5675 participants (55–75 years) from the PREDIMED-Plus study. At baseline and at
one year, we evaluated the creatinine-based estimated glomerular filtration rate (eGFR) and food-frequency questionnairesderived
dietary scores. Associations between four categories (decrease/maintenance and tertiles of increase) of each dietary
pattern and changes in eGFR (ml/min/1.73m2) or ≥ 10% eGFR decline were assessed by fitting multivariable linear or logistic
regression models, as appropriate.
Results Participants in the highest tertile of increase in 17-item erMedDiet Score showed higher upward changes in eGFR
(β: 1.87 ml/min/1.73m2; 95% CI: 1.00–2.73) and had lower odds of ≥ 10% eGFR decline (OR: 0.62; 95% CI: 0.47–0.82)
compared to individuals in the decrease/maintenance category, while Trichopoulou-MedDiet and DASH Scores were not
associated with any renal outcomes. Those in the highest tertile of increase in Protein Diet Score had greater downward
changes in eGFR (β: − 0.87 ml/min/1.73m2; 95% CI: − 1.73 to − 0.01) and 32% higher odds of eGFR decline (OR: 1.32;
95% CI: 1.00–1.75).
Conclusions Among elderly individuals with overweight/obesity and MetS, only higher upward change in the 17-item
erMedDiet score adherence was associated with better kidney function after one year. However, increasing Protein Diet Score
appeared to have an adverse impact on kidney health. Trial Registration Number: ISRCTN89898870 (Data of registration:
2014).CRUE-CSIC agreementSpringer NatureCIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN)Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigacion para la Salud (FIS)European Commission PI13/00673
PI13/00492
PI13/00272
PI13/01123
PI13/00462
PI13/00233
PI13/02184
PI13/00728
PI13/01090
PI13/01056
PI14/01722
PI14/00636
PI14/00618
PI14/00696
PI14/01206
PI14/01919
PI14/00853
PI14/01374
PI14/00972
PI14/00728The European Regional Development Fund PI14/01471
PI16/00473
PI16/00662
PI16/01873
PI16/01094
PI16/00501
PI16/00533
PI16/00381
PI16/00366
PI16/01522
PI16/01120
PI17/00764
PI17/01183
PI17/00855
PI17/01347
PI17/00525
PI17/01827
PI17/00532European Commission PI19/01226
PI19/00781
PI19/01560
PI19/01332
PI20/01802
PI20/00138
PI20/01532
PI20/00456
PI20/00339
PI20/00557
PI20/00886
PI20/01158Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-Plus grantEuropean Research Council (ERC)European Commission 340918Recercaixa grant 2013ACUP00194Junta de Andalucia PI0458/2013
PS0358/2016
PI0137/2018Generalitat ValencianaEuropean CommissionGeneral Electric PROMETEO/2017/017
PROMETEO 21/2021
SEMERGEN grantBoosting young talent call grant program for the development of IISPV research projects 2019-2021 2019/IISPV/03Societat Catalana d'Endocrinologia i Nutricio (SCEN) Clinical-Research Grant 2019CIBEROBN entitled: Lifestyle Interventions and Chronic Kidney Disease: Inflammation, Oxidative Stress and Metabolomic Profile (LIKIDI study) grantICREASpanish Government FPU17/06488European Commission PI17/00215
PI17/01441
PI17/00508
PI17/01732
PI17/00926
PI19/00957
PI19/00386
PI19/00309
PI19/01032
PI19/00576
PI19/0001
Associations Between the Modified Food Standard Agency Nutrient Profiling System Dietary Index and Cardiovascular Risk Factors in an Elderly Population
Background: Helping consumers to improve the nutritional quality of their diet is
a key public health action to prevent cardiovascular diseases (CVDs). The modified
version of the Food Standard Agency Nutrient Profiling System Dietary Index (FSAm-
NPS DI) underpinning the Nutri-Score front-of-pack label has been used in public
health strategies to address the deleterious consequences of poor diets. This study
aimed to assess the association between the FSAm-NPS DI and some CVD risk
factors including body mass index (BMI), waist circumference, plasma glucose levels,
triglyceride levels, high-density lipoprotein (HDL) and low-density lipoprotein (LDL)
cholesterol, and diastolic and systolic blood pressure.
Materials and Methods: Dietary intake was assessed at baseline and after
1 year of follow-up using a 143-item validated semi-quantitative food-frequency
questionnaire. Dietary indices based on FSAm-NPS applied at an individual level were
computed to characterize the diet quality of 5,921 participants aged 55–75 years
with overweight/obesity and metabolic syndrome from the PREDIMED-plus cohort.
Associations between the FSAm-NPS DI and CVD risk factors were assessed using
linear regression models.
Results: Compared to participants with a higher nutritional quality of diet (measured by
a lower FSAm-NPS DI at baseline or a decrease in FSAm-NPS DI after 1 year), those
participants with a lower nutritional quality of diet (higher FSAm-NPS DI or an increase
in score) showed a significant increase in the levels of plasma glucose, triglycerides,
diastolic blood pressure, BMI, and waist circumference (b coefficient [95% confidence
interval]; P for trend) (1.67 [0.43, 2.90]; <0.001; 6.27 [2.46, 10.09]; <0.001; 0.56 [0.08,
1.05]; 0.001; 0.51 [0.41, 0.60]; <0.001; 1.19 [0.89, 1.50]; <0.001, respectively). No
significant associations in relation to changes in HDL and LDL-cholesterol nor with
systolic blood pressure were shown.
Conclusion: This prospective cohort study suggests that the consumption of food
items with a higher FSAm-NPS DI is associated with increased levels of several major
risk factors for CVD including adiposity, fasting plasma glucose, triglycerides, and
diastolic blood pressure. However, results must be cautiously interpreted because no
significant prospective associations were identified for critical CVD risk factors, such as
HDL and LDL-cholesterol, and systolic blood pressure.official Spanish InstitutionsEuropean Commission PI13/00673
PI13/00492
PI13/00272
PI13/01123
PI13/00462
PI13/00233
PI13/02184
PI13/00728
PI13/01090
PI13/01056
PI14/01722
PI14/00636
PI14/00618The European Regional Development Fund PI16/01120
PI17/00764
PI17/01183
PI17/00855
PI17/01347
PI17/00525
PI17/01827
PI17/00532
PI17/00215
PI17/01441
PI17/00508Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-PlusEuropean Research Council (ERC)
European Commission 340918La Caixa Foundation 2013ACUP00194Junta de Andalucia PI0458/2013
PS0358/2016
PI0137/2018Center for Forestry Research & Experimentation (CIEF)European CommissionSEMERGEN grantICREA under the ICREA Academia programAgencia de Gestio d'Ajuts Universitaris de Recerca (AGAUR FI) 2021FI_B 00145Sara Borrell CD21/00045
PI20/00138
PI20/01532
PI20/00456
PI20/00339
PI20/00557
PI20/00886
PI20/01158
PI17/01732
PI17/00926
PI19/00957
PI19/00386
PI19/00309
PI19/01032
PI19/00576
PI19/00017
PI19/01226
PI19/00781
PI19/01560
PI19/01332
PI20/01802
PI14/00696
PI14/01206
PI14/01919
PI14/00853
PI14/01374
PI14/00972
PI14/00728
PI14/01471
PI16/00473
PI16/00662
PI16/01873
PI16/01094
PI16/00501
PI16/00533
PI16/00381
PI16/00366
PI16/0152
Association Among Polyphenol Intake, Uric Acid, and Hyperuricemia: A Cross-Sectional Analysis in a Population at High Cardiovascular Risk
BACKGROUND: Dietary polyphenol intake has been associated with a decreased risk of hyperuricemia, but most of this knowledge
comes from preclinical studies. The aim of the present study was to assess the association of the intake of different
classes of polyphenols with serum uric acid and hyperuricemia.
METHODS AND RESULTS: This cross-sectional
analysis involved baseline data of 6332 participants. Food polyphenol content
was estimated by a validated semiquantitative food frequency questionnaire and from the Phenol-Explorer
database.
Multivariable-adjusted
linear regression models with serum uric acid (milligrams per deciliter) as the outcome and polyphenol
intake (quintiles) as the main independent variable were fitted. Cox regression models with constant follow-up
time (t=1) were
performed to estimate the prevalence ratios (PRs) of hyperuricemia (≥7 mg/dL in men and ≥6 mg/dL in women). An inverse
association between the intake of the phenolic acid class (β coefficient, −0.17 mg/dL for quintile 5 versus quintile 1 [95% CI,
−0.27 to −0.06]) and hydroxycinnamic acids (β coefficient, −0.19 [95% CI, −0.3 to −0.09]), alkylmethoxyphenols (β coefficient,
−0.2 [95% CI, −0.31 to −0.1]), and methoxyphenols (β coefficient, −0.24 [95% CI, −0.34 to −0.13]) subclasses with serum uric
acid levels and hyperuricemia (PR, 0.82 [95% CI, 0.71–0.95];
PR, 0.82 [95% CI, 0.71–0.95];
PR, 0.80 [95% CI, 0.70–0.92];
and
PR, 0.79 [95% CI, 0.69–0.91];
respectively) was found. The intake of hydroxybenzoic acids was directly and significantly associated
with mean serum uric acid levels (β coefficient, 0.14 for quintile 5 versus quintile 1 [95% CI, 0.02–0.26])
but not with
hyperuricemia. CONCLUSIONS: In individuals with metabolic syndrome, a higher intake of some polyphenol subclasses (hydroxycinnamic
acids, alkylmethoxyphenol, and methoxyphenol) was inversely associated with serum uric acid levels and hyperuricemia.
Nevertheless, our findings warrant further research.European Research Council (ERC)
European Commission 2013-2018
340918official funding agency for biomedical research of the Spanish government
Instituto de Salud Carlos IIIEuropean Commission PI13/00673
PI13/00492
PI13/00272
PI13/01123
PI13/00462
PI13/00233
PI13/02184
PI13/00728
PI13/01090
PI13/01056
PI14/01722
PI14/00636
PI14/00618
PI14/00696
PI14/01206
PI14/01919Especial Action ProjectLa Caixa Foundation 2013ACUP00194Consejo Interinstitucional de Ciencia y Tecnologia (CICYT) AGL2016-75329-RCenter for Forestry Research & Experimentation (CIEF)European Commission PROMETEO/2017/017Generalitat de Catalunya SGR-2019Junta de Andalucia PI0458/2013
PS0358/2016
PI0137/2018SEMERGEN (Sociedad Espanola de Medicos de Atencion Primaria)European Cooperation in Science and Technology (COST)IDISBA (Instituto de Investigacion Sanitaria Islas Baleares)European Commission CIBEROBN CB06/03
CB12/03European Commission
European Commission Joint Research Centre EAT2BENI-CE_H2020_SFS2016Spanish Ministry of Science, Innovation and Universities for the Formacion de Profesorado Universitario FPU17/00785Instituto de Salud Carlos III, through the Fondo de Investigacion para la Salud - European Regional Development Fund PI16/00501
PI16/00533
PI16/00381
PI16/00366
PI16/01522
PI16/01120
PI17/00764
PI17/01183
PI17/00855
PI17/01347
PI17/00525
PI17/01827
PI17/00532
PI17/00215
PI17/01441
PI17/00508
PI17/01732
PI17/00926
PI19/00957
PI16/00473Instituto de Salud Carlos III
European Commission PI14/00853
PI14/01374
PI14/00972
PI19/00386
PI19/00309
PI19/01032
PI19/00576
PI19/00017
PI19/01226
PI19/00781
PI19/01560
PI16/00662
PI16/01873
PI16/01094
PI19/01332
PI14/00728
PI14/0147
Association between Dietary Diversity and All-Cause Mortality: A Multivariable Model in a Mediterranean Population with 18 Years of Follow-Up
The VNS study was supported by a grant from the Direccion General de Salud Publica, Generalitat Valenciana 1994 and the Fondo Investigacion Sanitaria (FIS 00/0985). This study has also received support from the Instituto de Salud Carlos III and FEDER funds (FIS PI13/00654) and Generalitat Valenciana AICO/2021/347.We evaluated the relationship between the dietary diversity score (DDS) and all-cause, CVD
and cancer mortality in an adult Mediterranean population. We analyzed the data of 1540 participants
from the Valencia Nutrition Survey. The DDS was estimated using a validated food frequency
questionnaire and was categorized into quartiles (Q), where the first quartile indicates the lowest
dietary diversity. Deaths were ascertained during an 18-year follow-up period. Cox regression models
were used to estimate hazard ratios (HR) and 95% confidence intervals (CI). There were 403 deaths
during the follow-up period (40% due to CVD). An inverse association was observed between the
DDS and all-cause and CVD mortality. Compared with participants in the lowest DDS quartile (Q1),
participants in the highest DDS quartile (Q4) showed 32% and 45% less risk of death for all-cause and
CVD mortality, in sex- and age-adjusted models, respectively. Regarding the food groups in the DDS,
an inverse association was identified between total vegetable consumption diversity and all-cause
and CVD mortality in the highest quartiles, (Q3 vs. Q1, HR: 0.70; 95% CI: 0.50, 0.99) and (Q4 vs. Q1,
HR: 0.52; 95% CI: 0.30, 0.91), respectively. This study suggests that a higher diversity in food intake,
particularly in vegetables, may be associated with a lower risk of all-cause and CVD mortality. This
association should be further investigated in other wider populations.Direccion General de Salud Publica
Generalitat ValencianaEuropean CommissionGeneral Electric AICO/2021/347Instituto de Salud Carlos III FIS 00/0985
Instituto de Salud Carlos III
European Commission
European Commission FIS PI13/0065
Long‑term efect of a dietary intervention with two‑healthy dietary approaches on food intake and nutrient density in coronary patients: results from the CORDIOPREV trial
Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. N.C.-I. is a recipient of the Juan de la Cierva Formación Programme. E.M.Y-S is a recipient of the Nicolás Monardes Programme (C1-0005–2019, Servicio Andaluz de Salud, Junta de Andalucía, Spain). A.P.A-L is supported by a Río-Hortega Programme (Instituto de Salud Carlos III). The CORDIOPREV study is supported by the Fundacion Patrimonio Comunal Olivarero. The sponsor was not involved in the design or carrying out the study, and its participation was limited to funding and providing the olive oil used in the study. CORDIOPREV trial also received additional funding from CITOLIVA, CEAS, Junta de Andalucia (Consejeria de Salud, Consejeria de Agricultura y Pesca, Consejeria de Innovacion, Ciencia y Empresa), Diputaciones de Jaen y Cordoba, Centro de Excelencia en Investigacion sobre Aceite de Oliva y Salud and Ministerio de Medio Ambiente, Medio Rural y Marino and the Spanish Government. It was also partly supported by research grants from the Ministerio de Ciencia e Innovacion (AGL2009-122270 to J L-M, FIS PI10/01041 to P. P.-M, FIS PI13/00023 to J. D.-L); Ministerio de Economia y Competitividad (AGL2012/39615 to J L-M); Consejeria de Salud, Junta de Andalucia (PI0193/09 to J. L.-M, PI-0252/09 to J. D.-L, and PI-0058/10 to P. P.-M, PI-0206–2013 to A. G.-R); Proyecto de Excelencia, Consejería de Economía, Innovación, Ciencia y Empleo (CVI-7450 to J. L.-M).Background Cardiovascular disease (CVD) is the leading cause of disease burden in the world by non-communicable
diseases. Nutritional interventions promoting high-quality dietary patterns with low caloric intake value and high nutrient
density (ND) could be linked to a better control of CVD risk and recurrence of coronary disease. This study aims to assess
the efects of a dietary intervention based on MedDiet or Low-Fat dietary intervention over changes in ND and food intake
after 1 and 7 years of follow-up of the CORDIOPREV study.
Methods We prospectively analyzed the results of the 802 coronary patients randomized to two healthy dietary patterns
(MedDiet=425, Low-Fat Diet=377) who completed the 7 years of follow-up and had all the dietary data need. Dietary
intake information obtained from a validated 137-item Food Frequency Questionnaire was used to calculate 1- and 7-year
changes in dietary intake and ND (measured as nutrient intake per 1000 kcal). T test was used to ascertain diferences in food
intake and ND between groups across follow-up time. Within-subject (dietary allocation group) diferences were analyzed
with ANOVA repeated measures.
Results From baseline to 7 years of follow-up, signifcant increases of vegetables, fruits, and whole cereals within groups
(p<0.001) was found. We found a higher increase in dietary intake of certain food groups with MedDiet in comparison with
Low-Fat Diet for vegetables (46.1 g/day vs. 18.1 g/day, p<00.1), fruits (121.3 g/day vs. 72.9 g/day), legumes (4.3 g/day vs.
0.16 g/day) and nuts (7.3 g/day vs. − 3.7 g/day). There was a decrease in energy intake over time in both groups, slightly
higher in Low-Fat Diet compared to MedDiet group (− 427.6 kcal/day vs. − 279.8 kcal/day at 1st year, and − 544.6 kcal/
day vs. − 215.3 kcal/day after 7 years of follow-up). ND of all the nutrients increased within group across follow-up time,
except for Saturated Fatty Acids (SFA), cholesterol and sodium (p<0.001).
Conclusions A comprehensive dietary intervention improved quality of diet, reducing total energy intake and increasing the
intake of healthy food groups and overall ND after 1 year and maintaining this trend after 7 years of follow-up. Our results
reinforce the idea of the participation in trials, enhance nutrition literacy and produces better nutritional outcomes in adult
patients with established CVD.
Clinical trial registry The trial was registered in 2009 at ClinicalTrials.gov (number NCT00924937)CITOLIVACentro de Excelencia en Investigacion sobre Aceite de Oliva y SaludConsejeria de Agricultura y PescaConsejeria de InnovacionConsejeria de SaludConsejeria de Salud, Junta de Andalucia
PI-0058/10, PI-0206–2013, PI-0252/09, PI0193/09Consejería de Economía, Innovación, Ciencia y Empleo
CVI-7450Diputaciones de Jaen y CordobaFundacion Patrimonio Comunal OlivareroMedio Rural y MarinoMinisterio de Ciencia e Innovacion
AGL2009-122270, FIS PI10/01041, FIS PI13/00023Spanish GovernmentCenter for East Asian Studies, Stanford UniversityMinisterio de Economía y Competitividad
AGL2012/39615Instituto de Salud Carlos IIIMinistério do Meio AmbienteJunta de Andalucí
Dietary diversity and depression: cross-sectional and longitudinal analyses in Spanish adult population with metabolic syndrome. Findings from PREDIMED-Plus trial
Objective: To examine the cross-sectional and longitudinal (2-year follow-up) associations
between dietary diversity (DD) and depressive symptoms.
Design: An energy-adjusted dietary diversity score (DDS) was assessed using a
validated FFQ and was categorised into quartiles (Q). The variety in each food
group was classified into four categories of diversity (C). Depressive symptoms
were assessed with Beck Depression Inventory-II (Beck II) questionnaire and
depression cases defined as physician-diagnosed or Beck II >= 18. Linear and
logistic regression models were used.
Setting: Spanish older adults with metabolic syndrome (MetS).
Participants: A total of 6625 adults aged 55–75 years from the PREDIMED-Plus
study with overweight or obesity and MetS.
Results: Total DDS was inversely and statistically significantly associated with
depression in the cross-sectional analysis conducted; OR Q4 v. Q1= 0·76 (95 %
CI (0·64, 0·90)). This was driven by high diversity compared to low diversity
(C3 v. C1) of vegetables (OR = 0·75, 95 % CI (0·57, 0·93)), cereals (OR = 0·72
(95 % CI (0·56, 0·94)) and proteins (OR = 0·27, 95 % CI (0·11, 0·62)). In the longitudinal
analysis, there was no significant association between the baseline DDS
and changes in depressive symptoms after 2 years of follow-up, except for DD
in vegetables C4 v. C1 = (β = 0·70, 95 % CI (0·05, 1·35)).
Conclusions: According to our results, DD is inversely associated with depressive
symptoms, but eating more diverse does not seem to reduce the risk of future
depression. Additional longitudinal studies (with longer follow-up) are needed
to confirm these findings.European Research Council (ERC)
European Commission 340918official funding agency for biomedical research of the Spanish Government, ISCIII through the Fondo de Investigacion para la Salud (FIS) - European Regional Development Fund PI13/00673
PI13/00492
PI13/00272
PI13/01123
PI13/00462
PI13/00233
PI13/02184
PI13/00728
PI13/01090
PI13/01056
PI14/01722
PI14/00636
PI14/00618
PI14/00696
PI14/01206
PI14/01919
PI14/00853
PI14/01374La Caixa Foundation 2013ACUP00194Junta de Andalucia PI0458/2013
PS0358/2016
PI0137/2018Center for Forestry Research & Experimentation (CIEF)European Commission PROMETEO/2017/017CIBEROBNEuropean Commission CB06/03Instituto de Salud Carlos IIIInternational Nut&Dried Fruit Council-FESNAD Ndegreesnd longitudinal analyses in Spanish adult population with metabolic syndrome. Findings from PREDIMED-Plus trial 201302
SEMERGEN
PI16/00473
PI16/00662
PI16/01873
PI16/01094
PI16/00501
PI16/00533
PI16/00381
PI16/00366
PI16/01522
PI16/01120
PI17/00764
PI17/01183
PI17/00855
PI17/01347
PI17/00525
PI17/01827
PI17/00532
PI17/00215
PI17/01441
PI17/00508
PI17/01732
PI17/0092
¿Es efectiva la intervención nutricional centrada en la pérdida de peso y mejora en la adherencia a Dieta Mediterránea sobre la densidad nutricional y la ingesta adecuada de nutrientes en población adulta española con sobrepeso y SM?
III Congreso de Alimentación, Nutrición y Dietética. Combinar la nutrición comunitaria y personalizada: nuevos retos
Higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study
This work was supported by the official Spanish Institutions for funding scientific biomedical research, CIBER Fisiopatologia de la Obesidad y Nutricio?n (CIBEROBN) and Instituto de Salud Carlos III (ISCIII) , through the Fondo de Investigacion para la Salud (FIS) , which is co-funded by the European Regional Development Fund (6 coordinated FIS projects leaded by JS-S and JoV, including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, PI19/01332, PI20/01802, PI20/00138, PI20/01532, PI20/00456, PI20/00339, PI20/00557, PI20/00886, PI20/01158) ; the Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-Plus grant and the Recercaixa (number 2013ACUP00194) grant to JS-S; grants from the European Research Council (Advanced Research Grant 2014-2019; agreement #340918) ; grants from the Consejeria de Salud de la Junta de Andalucia (PI0458/2013, PS0358/2016, PI0137/2018) ; the PROMETEO/2017/017 and PROMETEO/2021/021 grants from the Conselleria de Innovacio?n, Universidades, Ciencia y Sociedad digital de la Generalitat Valenciana; Grant PID2019-108858RB-I00 funded by AEI 10.13039/501100011033 and by "ERDF A way of making Europe"; the SEMERGEN grant; the AICO/2021/347 grants from the Generalitat Valenciana. This research was also partially funded by EU-H2020 Grants (Eat2beNICE/H2020-SFS-2016-2) ; and the Horizon 2020 PRIME study (Prevention and Remediation of Insulin Multimorbidity in Europe; grant agreement #847879) . JN is supported by a predoctoral grant from Ministerio de Ciencia, Innovacion y Universidades (FPU 20/00385) . SKN is supported by a postdoctoral fellowship from the Canadian Institutes of Health Research (CIHR) . JS-S, the senior author of this paper, was partially supported by ICREA under the ICREA Academia program. None of the funding sources took part in the design,collection, analysis, interpretation of the data, writing the report, or in the decision to submit the manuscript for publication.Background: Tree nuts and peanuts (henceforth, nuts) are nutrient-dense foods rich in neuroprotective components; thus, their consumption could benefit cognitive health. However, evidence to date is limited and inconsistent regarding the potential benefits of nuts for cognitive function.Objective: To prospectively evaluate the association between nut consumption and 2-y changes in cognitive performance in older adults at cognitive decline risk.Methods: A total of 6,630 participants aged 55 to 75 y (mean age 65.0 & PLUSMN;4.9 y, 48.4% women) with overweight/obesity and metabolic syndrome completed a validated semi-quantitative food frequency questionnaire and a comprehensive battery of neuropsychological tests at baseline and a 2-y follow-up. Composite cognitive scores were used to assess global, general, attention, and executive function domains. Nut consumption was categorized as 1 to 3 to 7 servings/wk (1 serving=30 g). Multivariable-adjusted linear regression models were fitted to assess associations between baseline nut consumption and 2-y cognitive changes.Results: Nut consumption was positively associated with 2-y changes in general cognitive function (P-trend 3 to 7 servings/wk showed more favorable changes in general cognitive performance (& beta; z-score [95% CI] = 0.06 [0.00,0.12] and 0.13 [0.06,0.20], respectively). No significant changes were observed in the multivariableadjusted models for other cognitive domains assessed.Conclusion: Frequent nut consumption was associated with a smaller decline in general cognitive performance over 2 y in older adults at risk of cognitive decline. Randomized clinical trials to verify our findings are warranted.Official Spanish InstitutionsInstituto de Salud Carlos III (ISCIII) , Fondo de Investigacion para la Salud (FIS) - European Regional Development Fund
PI13/00673,
PI13/00492,
PI13/00272,
PI13/01123,
PI13/00462,
PI13/00233,
PI13/02184,
PI13/00728,
PI13/01090,
PI13/01056,
PI14/01722,
PI14/00636,
PI14/00618,
PI14/00696,
PI14/01206,
PI14/01919,
PI14/00853,
PI14/01374,
PI14/00972,
PI14/00728,
PI14/01471,
PI16/00473,
PI16/00662,
PI16/01873,
PI16/01094,
PI16/00501,
PI16/00533,
PI16/00381,
PI16/00366,
PI16/01522,
PI16/01120,
PI17/00764,
PI17/01183,
PI17/00855,
PI17/01347,
PI17/00525,
PI17/01827,
PI17/00532,
PI17/00215,
PI17/01441,
PI17/00508,
PI17/01732,
PI17/00926,
PI19/00957,
PI19/00386,
PI19/00309,
PI19/01032,
PI19/00576,
PI19/00017,
PI19/01226,
PI19/00781,
PI19/01560,
PI19/01332,
PI20/01802,
PI20/00138,
PI20/01532,
PI20/00456,
PI20/00339,
PI20/00557,
PI20/00886,
PI20/01158La Caixa Foundation
2013ACUP00194Junta de Andalucía PI0458/2013, PS0358/2016, PI0137/2018, PROMETEO/2017/017Conselleria de Innovación, Universidades
PID2019-108858RB-I00,
AICO/2021/347Center for Forestry Research & Experimentation (CIEF) EU-H2020: Eat2beNICE/H2020-SFS-2016-2Horizon 2020 PRIME study 847879Spanish Government
FPU 20/00385Ministerio de Ciencia, Innovación y Universidades FPU 20/00385Canadian Institutes of Health Research (CIHR)ICREA under the ICREA Academia progra
Maternal Dietary Patterns during Pregnancy and Their Association with Gestational Weight Gain and Nutrient Adequacy
Several epidemiologic studies have shown an association between GestationalWeight Gain (GWG) and o spring complications. The GWG is directly linked to maternal dietary intake and women’s nutritional status during pregnancy. The aim of this study was (1) to assess, in a sample of Spanish pregnant women, the association between maternal dietary patterns and GWG and (2) to assess maternal dietary patterns and nutrient adequate intake according to GWG. A retrospective study was conducted in a sample of 503 adult pregnant women in five hospitals in Eastern Andalusia (Spain). Data on demographic characteristics, anthropometric values, and dietary intake were collected from clinical records by trained midwives. Usual food intake was gathered through a validated Food Frequency Questionnaire (FFQ), and dietary patterns were obtained by principal component analysis. Nutrient adequacy was defined according to European dietary intake recommendations for pregnant women. Regression models adjusted by confounding factors were constructed to study the association between maternal dietary pattern and GWG, and maternal dietary patterns and nutritional adequacy. A negative association was found between GWG and the Mediterranean dietary pattern (crude = -0.06, 95% CI: -0.11, -0.04). Independent of maternal dietary pattern, nutrient adequacy of dietary fiber, vitamin B9, D, E, and iodine was related to a Mediterranean dietary pattern (p < 0.05). A Mediterranean dietary pattern is related to lower GWG and better nutrient adequacy. The promotion of healthy dietary behavior consistent with the general advice promoted by the Mediterranean Diet (based on legumes, vegetables, nuts, olive oil, and whole cereals) will o er healthful, sustainable, and practical strategies to control GWG and ensure adequate nutrient intake during pregnancy.National Institute of Health Carlos III
PI11/0219
Physician–Patient Language Discordance and Poor Health Outcomes: A Systematic Scoping Review
Professor Khan is a distinguished investigator at the University
of Granada funded by the Beatriz Galindo (senior modality)
program of the Spanish Ministry of Education.The Supplementary Material for this article can be found
online at: https://www.frontiersin.org/articles/10.3389/fpubh.
2021.629041/full#supplementary-materialObjective: This systematic review assessed whether physician-patient language concordance, compared with discordance, is associated with better health outcomes.
Methods: A systematic literature search was conducted, without language restrictions, using PubMed, EMBASE, Web of Science, and PsycINFO, from inception to July 2020. We included studies that evaluated the effects of physician-patient language concordance on health outcomes. Articles were screened, selected, and data-extracted in duplicate. Review protocol was prospectively registered (PROSPERO, CRD42020157229).
Results: There were 541 citations identified through databases and eight citations through reverse search and Google Scholar. A total of 15 articles (84,750 participants) were included reporting outcomes within five domains: diabetes care (four studies), inpatient care (five studies), cancer screening (three studies), healthcare counseling (two studies), and mental health care (one study). Ten studies were of good quality, four were fair, and one was poor, according to the modified Newcastle-Ottawa Scale. Eight studies (53%) showed a significant negative association between language discordance and at least one clinical outcome. Five studies (33%) found no association.
Conclusion: Over half the evidence collated showed that physician-patient language concordance was associated with better health clinical outcomes.Spanish Governmen
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