PEREIRA, Francisco Maria Esteves

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Real fábrica da cordoaria

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Coutinho's method for the altitude

UID/MAT/00297/2019In the first aerial crossing of the South Atlantic, by Gago Coutinho and Sacadura Cabral in 1922, several methods of astronomical maritime navigation were used with adaptions to aerial navigation. In order to apply these methods, the navigator needed to know the approximate altitude of the aircraft so that its position could be determined. The instrument available at that time, the altimeter, did not give reliable values for altitude. Therefore, Coutinho had to devise a method that enabled the navigator to determine the altitude quickly and efficiently. The method Coutinho devised is based on a mathematical and geometrical procedure. In this paper, we study in detail Coutinho's method to determine altitude, with diagrams to aid understanding of the deductions and calculations. We also present a real example of how this method would be used during the flight.authorsversionpublishe

A obra náutica de João Baptista Lavanha (C. 1550-1624)

Tese de doutoramento, História (História dos Descobrimentos e Expansão), Universidade de Lisboa, Faculdade de Letras, 2012O objectivo central da presente dissertação é a análise da obra náutica de João Baptista Lavanha. Lavanha viveu na transição do século xvi para o xvii tendo desenvolvido quase toda a sua actividade intelectual após a instauração da União Ibérica. Personagem multifacetada, redigiu textos sobre arquitectura naval, cosmografia, genealogia, história e náutica. Iniciaremos a nossa análise com um apontamento biográfico sobre Lavanha. Além de pretendermos relatar os principais momentos da sua vida, estamos também interessados em perceber até que ponto as circunstâncias que o rodearam tiveram influência no modo como a sua carreira se desenvolveu. Quanto ao estudo dos seus contributos para a náutica, começaremos com um capítulo dedicado a todos os seus textos onde identificámos assuntos de náutica, mesmo que de um modo indirecto. Seguem-se três capítulos, sendo cada um deles dedicado a um texto distinto. O primeiro dos textos é o Tratado del arte de navegar. Trata-se de um conjunto de apontamentos das aulas que ministrou na Academia das Matemáticas, em Madrid. O seu conteúdo consiste essencialmente em assuntos de cariz mais teórico, baseando-se em Pedro Nunes, na maior parte dos temas apresentados. O segundo texto é o Regimento náutico. Estamos na presença de uma obra impressa redigida por Lavanha pouco depois de ter sido nomeado cosmógrafo-mor de Portugal. Era destinada a fornecer aos pilotos os conhecimentos necessários ao desempenho da sua profissão. Finalmente, o terceiro texto contém as tabelas de amplitude calculadas por Lavanha. O valor da amplitude servia para se obter a declinação das agulhas magnéticas, observando o Sol, no momento do seu nascimento, ou no ocaso.The main objective of this thesis is to examine the nautical texts of João Baptista Lavanha. Lavanha lived in the transition from the sixteenth to the seventeenth century, carring out most of his intellectual activity after the establishment of «União Ibérica». Multifaceted character, he wrote texts on naval architecture, cosmography, genealogy, history and nautical science. This analysis will start with a biographical note about Lavanha. We also intend to write about the most important moments of his life, and to understand to what extent the environment surrounding him interfered in the way his career developed. Regarding the study of his contributions to nautical, it begins with a chapter dedicated to all the texts which have identified issues of navigation, even in an indirect way. After we have three chapters, each dedicated to one individual text. The first is the text of the Tratado del arte de navegar. It contains notes from classes he taught at the Academy of Mathematics, in Madrid. Its content is essentially theoretical, based on Pedro Nunes, for the most part of the issues presented. The second text is the Regimento náutico. We are in the presence of a work printed by Lavanha shortly after being appointed chief cosmographer of Portugal. The text provides pilots with the knowledge needed to performing their jobs. Finally, the third text contains tables amplitude calculated by Lavanha. The amplitude was used to obtain the variation of the magnetic compass, observing the Sun at sunrise or at sunset

O corretor de rumos de Gago Coutinho e Sacadura Cabral

Na travessia aérea do Atlântico Sul, em 1922, foram usados métodos astronómicos de navegação, adaptados da navegação marítima. Para a sua aplicação era importante conhecer a posição estimada da aeronave com algum rigor. Na maior parte dos casos, o conhecimento da direção seguida pela aeronave e da sua velocidade, em relação ao ar, não são suficientes para determinar essa posição com rigor, pois o vento pode provocar desvios significativos no movimento da aeronave. A determinação do efeito do vento, conhecido como deriva, era fundamental para melhorar o rigor da posição estimada. Gago Coutinho e Sacadura Cabral conceberam um instrumento, o corretor de rumos, que permitia calcular, de uma forma expedita a deriva provocada pelo vento. Além disso, o corretor de rumos servia igualmente para determinar qual a direção para a qual deveria apontar a aeronave, de modo a seguir na direção desejada. Neste artigo será explicado em que consiste o problema da deriva assim como o processo de cálculo da mesma, usando o corretor de rumos. Serão apresentadas inúmeras ilustrações, para uma melhor compreensão dos procedimentos de cálculo, sendo igualmente apresentadas as principais fórmulas de cálculo que serviram de suporte teórico à construção do instrumento

Osteoporosis management during the COVID-19 pandemic - Position paper

verCOVID-19 pandemic significantly increased the already large number of victims of osteoporosis in Portugal. Osteoporosis outpatient clinics were either closed or had limited presential appointments. Many hospitals reduced orthopaedic services to make space for patients with COVID-19. In addition, the volunteer or forced sedentarism, as imposed by the pandemic, increased the risk of falls and fractures drastically. It urges to intensify the current efforts to improve the management of bone health and to prioritize fragility fracture care and prevention. This paper addresses the challenges in osteoporosis management during the COVID-19 pandemic and provides guidance on osteoporosis management. This position paper is a joint initiative of several health professionals and patients dedicated to osteoporosis.publishersversionpublishe

Efficacy and safety of percutaneous left atrial appendage closure in chronic kidney disease patients with atrial fibrillation : results of a 7-year registry

© The Author 2017. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.INTRODUCTION AND AIMS: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, the most devastating complication being thromboembolism leading to fatal or disabling stroke. Although oral anticoagulation (OAC) is the mainstay of prevention therapy in the general population, its benefit in chronic kidney disease (CKD) patients is less well defined. End-stage renal disease patients treated with vitamin K antagonists present increased risk of bleeding, accelerated cardiovascular calcification and increased risk of calciphylaxis. Left atrial appendage closure (LAAC) is performed to prevent complications in high-risk AF patients with contraindications to OAC and in AF patients with events despite OAC.info:eu-repo/semantics/publishedVersio

Comparative effectiveness and predictors of response to tumour necrosis factor inhibitor therapies in rheumatoid arthritis

Funding Information: positions on two Pfizer sponsored trials and has directed an educational course supported by Bristol Myers Squibb. He serves as an epidemiology consultant to CORRONA. J.A.P.S. has received honoraria as a speaker or consultant and benefited from research support from several pharmaceutical companies involved in the production of biologic agents (Abbott, Amgen, MSD, Pfizer and Roche), always at sums less than E10 000. All other authors have declared no conflicts of interest. Funding Information: Funding: This work was supported by a grant from Harvard-Portugal Program HMSP-ICS/SAU-ICT/0002/ 2010.Objectives: Adalimumab, etanercept and infliximab are effective TNF inhibitors (TNFis) in the treatment of RA, but no randomized clinical trials have compared the three agents. Prior observational data are not consistent. We compared their effectiveness over 1 year in a prospective cohort.Methods: Analyses were performed on subjects' first episode of TNFi use in the Rheumatic Diseases Portuguese Register, Reuma.pt. The primary outcome was the proportion of patients with European League Against Rheumatism good response sustained at two consecutive observations separated by 3 months during the first year of TNFi use. Comparisons were performed using conventional adjusted logistic regression, as well as matching subjects across the three agents using a propensity score. In addition, baseline predictors of treatment response to TNFi were identified.Results: The study cohort included 617 RA patients, 250 starting etanercept, 206 infliximab and 161 adalimumab. Good response was achieved by 59.6% for adalimumab, 59.2% for etanercept and 51.9% for infliximab (P = 0.21). The modelled probability of good response did not significantly differ across agents (etanercept vs adalimumab OR = 0.97, 95% CI 0.55, 1.71; etanercept vs infliximab OR = 1.25, 95% CI 0.74, 2.12; infliximab vs adalimumab OR = 0.80, 95% CI 0.47, 1.36). Matched propensity score analyses also showed no significant treatment response differences. Greater educational attainment was a predictor of better response, while smoking, presence of ACPA, glucocorticoid use and worse physician assessment of disease activity at baseline each predicted a reduced likelihood of treatment response.Conclusion: Over 1 year, we found no difference in effectiveness between adalimumab, etanercept and infliximab.publishersversionpublishe

Thrombus aspiration in patients with ST-elevation myocardial infarction: results of a national registry of interventional cardiology

BACKGROUND: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. METHODS: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). RESULTS: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). CONCLUSIONS: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI..info:eu-repo/semantics/publishedVersio