14 research outputs found

    Wallet-Based Transaction Fraud Prevention Through LightGBM With the Focus on Minimizing False Alarms

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    E-wallets’ rising popularity can be attributed to the fact that they facilitate a wide variety of financial activities such as payments, transfers, investments, etc., and eliminate the need for actual cash or cards. The confidentiality, availability, and integrity of a user’s financial information stored in an electronic wallet can be compromised by threats such as phishing, malware, and social engineering; therefore, fintech platforms employ intelligent fraud detection mechanisms to mitigate the problem. The purpose of this study is to detect fraudulent activity using cutting-edge machine learning techniques on data obtained from the leading e-wallet platform in Turkey. After a comprehensive analysis of the dataset’s features via feature engineering procedures, we found that the LightGBM approach had the highest detection accuracy of fraudulent activity with 97% in the experiments conducted. An additional key objective of reducing false alerts was accomplished, as the number of false alarms went from 13,024 to 6,249. This approach resulted in the establishment of a machine-learning model suitable for use by relatively small fraud detection teams

    A study on the antioxidant capacities of some benzimidazoles in rat tissues

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    Seven benzimidazole compounds were synthesized and their in vitro effects on rat liver, lung and kidney microsomal NADPH-dependent lipid peroxidation (LP) levels were determined. The significant decrease in male rat liver microsomal LP level was noted only by the compound 4 at 10(-4) M (20%) and 10(-3) M (40%) concentrations whereas the other compounds were ineffective. In lung, only the compound 6 at 10(-4) M concentration exhibited significant alteration, i.e. 56% increase, in LP level. In kidney, however, apart from the compound 4, all the compounds increased LP level(35-52%) significantly. The classical antioxidant, butylated hydroxy toluene (BHT): at 10(-4) M concentration, significantly decreased LP level about 70%, in all the tissues studied. To clarify the effects of compounds 4 and 6 on LP, the responses of some CYPs, which are active in producing reactive oxygen species, to these compounds were also investigated. The compound 4 at 10(-4) and 10(-3) M concentrations inhibited the hepatic microsomal ethoxyresorufin O-deethylase (EROD) (37 and 65%,) and pentoxyresorufin O-depenthylase (PROD) (14 and 62%) enzyme activities significantly. However, it did not alter the hepatic microsomal NADPH-cytochrome P450-reductase activity. BHT, at 10(-3) M concentration, significantly inhibited hepatic microsomal EROD (73%), PROD (62%) and NADPH-cytochrome P450 reductase (17%) enzyme activities. Caffeine (10(-3) M) and SKF 525A (10(-3) M), which are specific inhibitors of EROD and PROD enzyme activities, significantly decreased the enzyme activities 33 and 77%, respectively. Caffeine was unable to alter hepatic microsomal NADPH-cytochrome P450 reductase enzyme activity whereas SKF 525A significantly inhibited(80%) of it. In lung and kidney, the compound 6 at 10(-4) M concentration significantly increased EROD (44 and 19%) and PROD (103 and 86%) enzyme activities. However, the elevation of PROD enzyme activity in both tissues was observed to be more pronounced than that of EROD enzyme activity. This compound was ineffective on lung and kidney microsomal P450-reductase enzyme activity. These results reveal that the synthesized benzimidazoles have variable tissue dependent in vitro effects on LP due to their distinct effects on CYP activities but not on NADPH-cytochrome P450 reductase activity in rats. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved

    Surgical risk assessment for gynecological oncologic patients

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    Objective: Preoperative surgical risk assessment is important in terms of postoperative morbidity and mortality. Therefore, it is necessary to evaluate the efficacy and safety of these surgeries via an ideal risk assessment model, and reduce risks via applying some findings (for instance, perioperative beta-blockers). There are some risk assessment systems, but these have generally not been verified for patients with gynecologic cancer. The aim of this study was to assess the risk of surgery for gynecological oncologic patients and suggest an easy risk assessment model and risk reduction by applying our findings

    Effect of using magnifying loupe glasses on lymphocele formation and surgical outcomes in gynecologic oncology

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    Objective: To investigate the effect of using magnifying loupes during surgery on surgical outcomes and lymphocele formation

    CHEMICAL COMPOSITION AND ANTIBACTERIAL EVALUATION OF THE ESSENTIAL OILS OF FERULAGO AUCHERI BOISS. FROM DIFFERENT LOCALITIES

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    Air dried and crushed fruits of Ferulago aucheri Boiss. (Apiaceae) from Southern and Western regions of Turkey were subjected to hydrodistillation to obtain essential oils, which were subsequently analyzed by GC-FID and GC/MS. Seventy seven compounds representing 95.9% and 127 compounds representing 86.5% of the fruit oils have been characterized for samples of F. aucheri from Antalya (oil A) and Manisa (oil B) provinces, respectively. Monoterpenes comprised 83.6% of the oil A with limonene (43.1%), alpha-pinene (18.3%) and myrcene (7.0%) as major constituents. Sesquiterpenes (72.7%) prevailed in the oil B, with germacrene D (25.7%) and (2E,6E)-farnesol (8.0%) as major constituents. Both essential oils were also evaluated for their antibacterial activity against eight Gram (+) and Gram (-) strains by microdilution method. The oils displayed moderate to weak inhibitory activity (MIC 0.25-3 mg/mL). The oils were found to be the most active against Pseudomonas aeruginosa when compared with antimicrobial standards. Antibacterial activity of the oils appeared non-selective when comparing Gram (+) and Gram (-) strains

    A study on the antioxidant activities of some new benzazole derivatives

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    The in vitro antioxidant properties of some new benzazole derivatives ( 1–10 ) such as benzoxazoles, ben- zimidazoles, and benzothiazoles were determined by their effects on the rat liver microsomal NADPH- dependent lipid peroxidation (LP) level, the scavenging of superoxide anion and the stable radical 2,2- diphenyl-1-picrylhydrazyl (DPPH). Compounds 1 , 2 , 4 and 6 , showed potent scavenging effect on super- oxide radical at 10 –3 M. Compound 8, 5-nitro-2-(phenoxymethyl)benzimidazole, strongly inhibited lipid peroxidation at 10 –3 M concentration

    Synthesis and Antioxidant Properties of Novel Benzimidazole Derivatives

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    Some novel benzimidazole derivatives carrying thiosemicarbazide and triazole moieties at the N1 position were synthesized and their in vitro effects on rat liver microsomal NADPH-dependent lipid peroxidation (LP) levels determined by measuring the formation of 2-thiobarbituric acid reactive substance. The free radical scavenging properties of the compounds were also examined in vitro by determining the capacity to scavenge superoxide anion formation and the interaction with the stable free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH). The compounds showed a significant effect in the above tests except to scavenge superoxide anion formation.Wo
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