Proyecto de almacén de productos químicos de una industria de tratamiento de jeans en la localidad de Aldaia (Valencia)

Una empresa del sector textil especializada en el acabado de prendas vaqueras realiza un encargo de traslado de sus instalaciones. La localización escogida para la nueva planta es el polígono industrial de Aldaia, Valencia. El ingeniero, autor del presente trabajo, debe estudiar y comprender el proceso industrial a llevar a cabo para identificar las principales características y amenazas que supone un incorrecto almacenamiento de los productos químicos implicados para poder diseñar una instalación segura. Para conseguirlo, se clasifican estos productos. En función de esta clasificación se toman una serie de decisiones, como distancias mínimas de los tanques a otros elementos de la planta, material de los depósitos, posibilidad de almacenamiento conjunto y la mejor alternativa de distribución en planta. La correcta ejecución de las decisiones anteriores será posible mediante una correcta selección de las características de los cubetos de retención, la existencia de pavimento en la planta industrial, cerramientos y carpintería metálica, venteos y alivio de presión así como sistemas que garanticen la seguridad frente a incendio o rayos. Estos elementos quedan también a cargo del ingeniero proyectista. Adicionalmente se proporcionan unas instrucciones para el uso, conservación y seguridad de la instalación. Finalmente, se presenta al cliente (la empresa promotora) unos cuadros de presupuesto que indican de forma clara y concisa la inversión a realizar.A company in the textile sector specialized in the finishing of denim garments carries out an order to transfer its facilities. The chosen location for the new plant is the industrial park of Aldaia, Valencia. The engineer, author of the present work, must study and understand the industrial process to be carried out to identify the main characteristics and threats posed by the incorrect storage of the chemical products involved in order to design a safe installation. To achieve this, these products are classified. Depending on this classification, a series of decisions will be taken, such as minimum distances from these to other elements of the plant, material from their container tanks, the possibility of joint storage and the best alternative distribution in the plant. The correct execution of the previous decisions will be possible through a correct selection of the characteristics of the retention basins, the existence of pavement in the industrial plant, enclosures and metal carpentry, vents and pressure relief as well as systems that guarantee safety against fire or lightning. These elements are also the responsibility of the design engineer. Additionally, instructions for the use, conservation and safety of the installation are provided. Finally, the client (the promoter company) is presented with budget tables that clearly and concisely indicate the investment to be made.Una empresa del sector tèxtil especialitzada en l'acabat de peces vaqueres realitza un encàrrec de trasllat de les seues instal·lacions. La localització escollida per a la nova planta és el polígon industrial d'Aldaia, València. L'enginyer, autor del present treball, ha d'estudiar i comprendre el procés industrial a dur a terme per identificar les principals característiques i amenaces que suposa un incorrecte emmagatzematge dels productes químics implicats per poder dissenyar una instal·lació segura. Per aconseguir-ho, es classifiquen aquests productes. En funció d'aquesta classificació es prendran una sèrie de decisions, com a distàncies mínimes d'aquests a altres elements de la planta, material de les seves tancs contenidors, possibilitat d'emmagatzematge conjunt i la millor alternativa de distribució en planta. La correcta execució de les decisions anteriors serà possible mitjançant una correcta selección d’unes característiques de les cubetes de retenció, l'existència de paviment a la planta industrial, tancaments i fusteria metàl·lica, ventilació i alleujament de pressió així com sistemes que garanteixen la seguretat davant incendi o llamps. Aquests elements queden també a càrrec de l'enginyer projectista. Addicionalment es proporciona unes instruccions per a l'ús, conservació i seguretat de la instal·lació. Finalment, es presenta al client (l'empresa promotora) uns quadres de pressupost que indiquin de forma clara i concisa la inversió a realizar.Campos Castello, FJ. (2018). Proyecto de almacén de productos químicos de una industria de tratamiento de jeans en la localidad de Aldaia (Valencia). http://hdl.handle.net/10251/105630TFG

Análise e identificação de oportunidade de melhoria a partir da aplicação do pensamento Lean

Trabalho Final de Mestrado para obtenção do grau de Mestre em Engenharia e Gestão IndustrialO pensamento Lean se traduz pelas ações de definição de valor, redução de desperdícios e aplicação da melhoria contínua. A presente pesquisa objetiva caracterizar a metodologia do Lean Manufacturing e os princípios norteadores, tendo em consideração as suas aplicabilidades e resultados positivos na produtividade das indústrias. Para tanto, foi realizada uma revisão de literatura em livros e artigos científicos para o levantamento das referências bibliográficas existentes sobre o assunto com enfoque no resultado e melhoria apresentada após sua implementação. A revisão de literatura permitiu observar que a aplicação dos princípios do Lean Manufacturing é capaz de aumentar significativamente a produtividade e a eficiência das empresas de diversos mercados uma vez que é transversal e adaptável. Nesta dissertação é demonstrado um modelo de aplicação do Lean Manufacturing, baseado em seus princípios e ferramentas, que levou a redução de desperdícios e paragens de máquinas e o aumento de produtividade em 61% numa indústria de fabricação de bicicletas. O Pensamento Lean é tão poderoso que é capaz de alterar e melhorar desde pequenos processos até mesmo a cultura de uma empresa e torná-la mais rentável por meio da solução de problemas, eliminação de desperdícios, padronização de processos e aumento da satisfação dos funcionários, a refletir consequentemente na redução de custos e aumento da produtividade e eficiência das operações.Lean Thinking translates into actions to define value, reduce waste, and apply continuous improvement. The present research aims to characterize the Lean methodology, the guiding principles, considering its applicability and positive productivity results in the industry. To this end, a literature review was carried out in books and scientific articles to survey the existing bibliographic references on the subject with a focus on the result and improvement presented after its implementation. The literature review allowed us to observe that the application of Lean principles is capable to significantly increase the productivity and efficiency of companies in different markets since it is transversal and adaptable. This dissertation demonstrates an application model of Lean Manufacturing, based on its principles and tools, which led to a reduction in waste, machine downtime and increase productivity by 61% in a bicycle Manufacturing industry. The Lean Thinking is so powerful that it can change and improve from small processes to even the culture of a company and make it more profitable by solving problems, eliminating waste, standardizing processes, and increasing employee satisfaction, consequently reflected in cost reduction and increased productivity and efficiency of operations.info:eu-repo/semantics/publishedVersio

Empty forest or empty rivers? A century of commercial hunting in Amazonia

The Amazon basin is the largest and most species-rich tropical forest and river system in the world, playing a pivotal role in global climate regulation and harboring hundreds of traditional and indigenous cultures. It is a matter of intense debate whether the ecosystem is threatened by hunting practices, whereby an “empty forest” loses critical ecological functions. Strikingly, no previous study has examined Amazonian ecosystem resilience through the perspective of the massive 20th century international trade in furs and skins. We present the first historical account of the scale and impacts of this trade and show that whereas aquatic species suffered basin-wide population collapse, terrestrial species did not. We link this differential resilience to the persistence of adequate spatial refuges for terrestrial species, enabling populations to be sustained through source-sink dynamics, contrasting with unremitting hunting pressure on more accessible aquatic habitats. Our findings attest the high vulnerability of aquatic fauna to unregulated hunting, particularly during years of severe drought. We propose that the relative resilience of terrestrial species suggests a marked opportunity for managing, rather than criminalizing, contemporary traditional subsistence hunting in Amazonia, through both the engagement of local people in community-based comanagement programs and science-led conservation governance

Fluidoterapia em pacientes críticos: uma análise comparativa entre solução balanceada e solução salina

Introdução: A administração de soluções cristaloides na fluidoterapia de pacientes críticos é uma decisão complexa devido a diferentes efeitos bioquímicos e clínicos. Este estudo revisa a literatura atualizada, destacando a importância da escolha entre solução balanceada e salina. Metodologia: Realizamos uma revisão abrangente de dezoito artigos publicados entre 2014 e 2021, explorando os efeitos das soluções cristalóides na fluidoterapia em pacientes críticos, considerando evidências da literatura científica. Discussão: Soluções balanceadas e salinas apresentam variações na acidose metabólica, eletrólitos e função renal, mas a influência clínica permanece incerta. Esses ensaios clínicos, como o protocolo FISSH, são cruciais para orientar práticas clínicas. Conclusão: A decisão sobre soluções cristalóides na fluidoterapia de pacientes críticos requer abordagem individualizada. É necessária uma pesquisa contínua para guiar a tomada de decisões clínicas informadas e melhorar os resultados para esses pacientes

Correlation of enthesitis indices with disease activity and function in axial and peripheral spondyloarthritis : a cross-sectional study comparing MASES, SPARCC and LEI

Background: The presence of enthesitis is associated with higher disease activity, more disability and incapacity to work and a poorer quality of life in spondyloarthritis (SpA). There is currently no consensus on which clinical score should be used to assess enthesitis in SpA. The objective of the present work was to compare the correlation of three enthesitis indices (MASES, SPARCC and LEI) with measures of disease activity and function in a heterogeneous population of patients with axial and peripheral SpA. Methods: A cross-sectional study was conducted in three Brazilian public university hospitals; patients fulfilling ASAS classification criteria for peripheral or axial SpA were recruited and measures of disease activity and function were collected and correlated to three enthesitis indices: MASES, SPARCC and LEI using Spearman’s Correlation index. ROC curves were used to determine if the the enthesitis indices were useful to discriminate patients with active disease from those with inactive disease. Results: Two hundred four patients were included, 71.1% (N = 145) fulfilled ASAS criteria for axial SpA and 28.9% (N = 59) for peripheral SpA. In axial SpA, MASES performed better than LEI (p = 0.018) and equal to SPARCC (p = 0.212) regarding correlation with disease activity (BASDAI) and function (BASFI). In peripheral SpA, only MASES had a weak but statistical significant correlation with DAS28-ESR (rs 0.310 p = 0.05) and MASES had better correlation with functional measures (HAQ) than SPARCC (p = 0.034). Conclusion: In this sample composed of SpA patients with high coexistence of axial and peripheral features, MASES showed statistical significant correlation with measures of disease activity and function in both axial and peripheral SpA

Five-year microevolution of a multidrug-resistant Mycobacterium tuberculosis strain within a patient with inadequate compliance to treatment

Background: Whole-genome sequencing has shown that the Mycobacterium tuberculosis infection process can be more heterogeneous than previously thought. Compartmentalized infections, exogenous reinfections, and microevolution are manifestations of this clonal complexity. The analysis of the mechanisms causing the microevolution —the genetic variability of M. tuberculosis at short time scales— of a parental strain into clonal variants with a patient is a relevant issue that has not been yet completely addressed. To our knowledge, a whole genome sequence microevolution analysis in a single patient with inadequate adherence to treatment has not been previously reported. Case presentation: In this work, we applied whole genome sequencing analysis for a more in-depth analysis of the microevolution of a parental Mycobacterium tuberculosis strain into clonal variants within a patient with poor treatment compliance in Argentina. We analyzed the whole-genome sequence of 8 consecutive Mycobacterium tuberculosis isolates obtained from a patient within 57-months of intermittent therapy. Nineteen mutations (9 short-term, 10 fixed variants) emerged, most of them associated with drug resistance. The first isolate was already resistant to isoniazid, rifampicin, and streptomycin, thereafter the strain developed resistance to fluoroquinolones and pyrazinamide. Surprisingly, isolates remained susceptible to the pro-drug ethionamide after acquiring a frameshift mutation in ethA, a gene required for its activation. We also found a novel variant, (T-54G), in the 5′ untranslated region of whiB7 (T-54G), a region allegedly related to kanamycin resistance. Notably, discrepancies between canonical and phage-based susceptibility testing to kanamycin were previously found for the isolate harboring this mutation. In our patient, microevolution was mainly driven by drug selective pressure. Rare short-term mutations fixed together with resistance-conferring mutations during therapy. Conclusions: This report highlights the relevance of whole-genome sequencing analysis in the clinic for characterization of pre-XDR and MDR resistance profile, particularly in patients with incomplete and/or intermittent treatment.Fil: Fernández Do Porto, Darío Augusto. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Calculo. - Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Calculo; ArgentinaFil: Monteserin, Johana. Dirección Nacional de Instituto de Investigación.Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Campos, Josefina. Dirección Nacional de Instituto de Investigación.Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"; ArgentinaFil: Sosa, Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Matteo, Mario José. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Tisioneumonología "raúl F. Vaccarezza".; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; ArgentinaFil: Serral, Federico. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Calculo. - Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Calculo; ArgentinaFil: Yokobori, Noemí. Dirección Nacional de Instituto de Investigación.Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Fernández Benevento, Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Poklepovich, Tomás. Dirección Nacional de Instituto de Investigación.Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"; ArgentinaFil: Pardo, Agustin Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Wainmayer, Ingrid Cinthia. Dirección Nacional de Instituto de Investigación.Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"; ArgentinaFil: Símboli, Norberto Fabián. Dirección Nacional de Instituto de Investigación.Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"; ArgentinaFil: Castello, Florencia. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Cálculo; ArgentinaFil: Paul, Roxana Elizabeth. Dirección Nacional de Instituto de Investigación.Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"; ArgentinaFil: Marti, Marcelo Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: López, Beatriz Graciela. Dirección Nacional de Instituto de Investigación.Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"; ArgentinaFil: Turjanski, Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Ritacco, Gloria Viviana. Dirección Nacional de Instituto de Investigación.Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Alteração da massa corporal e do consumo alimentar de ratos suplementados com whey proteins

Introduction: Whey proteins have received great attention because of their benefits on skeletal muscle hypertrophy, body fat reduction, performance, appetite regulation, immune system regulation, regulation of the lipid profile and the combat against metabolic stress. In this sense, their importance is often overestimated, leading athletes and physical activity individuals to consume very high doses of protein, without the guarantee of additional benefits.  Aim: For 12 weeks quantify the evolution of food intake and total body mass of Wistar rats supplemented with whey proteins with dosages of 2, 4, 6g/kg/day. Materials and methods: Approval protocol of the Ethics Committee on the Use of Animals of the Federal University of Maranhão nº 23115.014424 / 2015-54). An experimental research design was adopted with the rats being randomly distributed in 4 groups: Control Group (C), Supplemented groups (W2, W4, W6); the study was performed with 38 male Rattus novergicus Wistar rats with initial age of 60 days and body mass between 218 and 323 grams; supplementation with whey proteins dissolved in water followed the dosages 2, 4 and 6 g / kg / day supplementation was performed for 12 weeks, daily, three times a day, by volume of 5 ml, with an hour interval between each gavage. Variables were tested for distribution using the Shapiro-Wilk test (P> 0.05). The data of the feed consumption were analyzed by the ANOVA test; the classification variable was the interaction between feed consumption or body mass and supplementation (C, W2, W4, W6); the Tukey post-test was used to determine the statistical differences between the groups (C, W2, W4, W6), GraphPad Prism 7 software was used. Results: The mean intake of rations in the control group did not present a statistically significant difference in relation to the Whey 4 group at weeks 1 (p=0,3450), 2 (p=0,1027), 3 (p=0,1595), 4 (p=0,5572) and 5 (p=0,2539). There was a statistically significant difference in the increase of the total body mass of the control group compared to the Whey 4 group at weeks 10 (p=0,0454), 12 (p=0,0348) and at the final week (p=0,0138). Likewise, there was a significant statistical difference in the increase of the total body mass of the control group compared to the Whey group 6 in the final week (p=0,0048). In the same sense, there was a statistically significant difference in the total body mass increase of the Whey 2 group compared to the Whey 6 group in weeks 1 (p=0,0210), 2 (p=0,0434) and in the final week (p=0,0289). Discussion: Diets with high protein content play an important role in satiety due to its involvement with intestinal production of several anorectic hormones, which in turn stimulate the vagus nerve, promoting neuronal stimuli to the solitary tract nucleus, signaling satiety. As a result, the long-term ingestion of a high-protein diet reduces not only food intake, but also body mass and body adiposity in rats. Conclusion: Supplementation with serum whey proteins at doses of 4 and 6 g/kg/day in sedentary animals conferred stability over total body weight and a significant reduction in feed intake over 12 weeks. Supplementation with serum whey proteins at 2 g/kg/day in sedentary animals did not lead to a reduction in the average feed intake and showed a similar effect to the other doses on total body weight.Introdução: As whey proteins tem recebido grande atenção por conta de seus benefícios sobre a hipertrofia muscular esquelética, redução de gordura corporal, performance, regulação do apetite, regulação do sistema imunológico, regulação do perfil lipídico e combate ao estresse metabólico. Diante disso, a sua importância muitas vezes é superestimada, levando atletas e indivíduos praticantes de atividades físicas a consumirem doses muito elevadas de proteínas, sem a garantia de benefícios adicionais. Objetivo: Quantificar durante 12 semanas a alteração do consumo de ração e da massa corporal total de ratos wistar suplementados por whey proteins nas doses de 2, 4, 6g/kg/dia. Materiais e Métodos: Protocolo de aprovação da Comissão de Ética no Uso de Animais da Universidade Federal do Maranhão nº 23115.014424/2015-54). Foi adotado delineamento de pesquisa experimental com os ratos sendo distribuídos aleatoriamente em 4 grupos: Grupo Controle (C), Grupos suplementados (W2, W4, W6); o estudo foi realizado com 38 Rattus novergicus machos da linhagem Wistar com idade inicial de 60 dias e massa corporal entre 218 e 323 gramas; a suplementação com whey proteins dissolvidas em água seguiu as dosagens 2, 4 e 6 g/kg/dia a suplementação foi realizada durante 12 semanas, diariamente, três vezes por dia, em volume de 5ml, com uma hora de intervalo entre cada gavagem. As variáveis ​​foram testadas quanto à distribuição utilizando o teste de Shapiro-Wilk (p>0,05). Os dados do consumo de ração, foram analisados pelo teste ANOVA; a variável de classificação foi a interação entre o consumo de ração ou massa corporal e a suplementação (C, W2, W4, W6); o pós-teste de Tukey foi utilizado para determinar as diferenças estatísticas entre os grupos (C, W2, W4, W6), utilizou-se o software GraphPad Prism 7. Resultados: A média de consumo de ração no grupo controle não apresentou diferença estatística significativa em relação ao grupo Whey 4 nas semanas 1 (p=0,3450), 2 (p=0,1027), 3 (p=0,1595), 4 (p=0,5572) e 5 (p=0,2539). Houve diferença estatística significativa no aumento da massa corporal total do grupo controle em comparação ao grupo Whey 4 nas semanas 10 (p=0,0454), 12 (p=0,0348) e na semana final (p=0,0138). Do mesmo modo, houve diferença estatística significativa no aumento da massa corporal total do grupo controle em comparação ao grupo Whey 6 na semana final (p=0,0048). Nesse mesmo sentido, houve diferença estatística significativa no aumento massa corporal total do grupo Whey 2 em comparação ao grupo Whey 6 nas semanas 1 (p=0,0210), 2 (p=0,0434) e na semana final (p=0,0289). Discussão: Dietas com altos teores de proteínas desempenham um papel importante no surgimento da saciedade em função do seu envolvimento com a produção a nível intestinal de diversos hormônios anorexígenos que por sua vez estimulam o nervo vago, promovendo estímulos neuronais para o núcleo trato solitário, sinalizando saciedade. Em função disso, a ingestão a longo prazo de uma dieta rica em proteínas diminui não só a ingestão de alimentos, mas também a massa corporal e a adiposidade corporal em ratos. Conclusão: A suplementação com as proteínas do soro do leite nas doses de 4 e 6g/kg/dia em ratos sedentários conferiram estabilidade em relação a massa corporal total e redução significativa do consumo de ração ao longo de 12 semanas. A suplementação com as proteínas do soro do leite na dose de 2g/kg/dia em ratos sedentários não promoveu redução no consumo médio de ração e apresentou efeito semelhante as demais doses sobre a massa corporal total

Alteration of food consumption and body mass of whey proteins supplemented rats

Introduction: Whey proteins have received great attention because of their benefits on skeletal muscle hypertrophy, body fat reduction, performance, appetite regulation, immune system regulation, regulation of the lipid profile and the combat against metabolic stress. In this sense, their importance is often overestimated, leading athletes and physical activity individuals to consume very high doses of protein, without the guarantee of additional benefits.  Aim: For 12 weeks quantify the evolution of food intake and total body mass of Wistar rats supplemented with whey proteins with dosages of 2, 4, 6g/kg/day. Materials and methods: Approval protocol of the Ethics Committee on the Use of Animals of the Federal University of Maranhão nº 23115.014424 / 2015-54). An experimental research design was adopted with the rats being randomly distributed in 4 groups: Control Group (C), Supplemented groups (W2, W4, W6); the study was performed with 38 male Rattus novergicus Wistar rats with initial age of 60 days and body mass between 218 and 323 grams; supplementation with whey proteins dissolved in water followed the dosages 2, 4 and 6 g / kg / day supplementation was performed for 12 weeks, daily, three times a day, by volume of 5 ml, with an hour interval between each gavage. Variables were tested for distribution using the Shapiro-Wilk test (P> 0.05). The data of the feed consumption were analyzed by the ANOVA test; the classification variable was the interaction between feed consumption or body mass and supplementation (C, W2, W4, W6); the Tukey post-test was used to determine the statistical differences between the groups (C, W2, W4, W6), GraphPad Prism 7 software was used. Results: The mean intake of rations in the control group did not present a statistically significant difference in relation to the Whey 4 group at weeks 1 (p=0,3450), 2 (p=0,1027), 3 (p=0,1595), 4 (p=0,5572) and 5 (p=0,2539). There was a statistically significant difference in the increase of the total body mass of the control group compared to the Whey 4 group at weeks 10 (p=0,0454), 12 (p=0,0348) and at the final week (p=0,0138). Likewise, there was a significant statistical difference in the increase of the total body mass of the control group compared to the Whey group 6 in the final week (p=0,0048). In the same sense, there was a statistically significant difference in the total body mass increase of the Whey 2 group compared to the Whey 6 group in weeks 1 (p=0,0210), 2 (p=0,0434) and in the final week (p=0,0289). Discussion: Diets with high protein content play an important role in satiety due to its involvement with intestinal production of several anorectic hormones, which in turn stimulate the vagus nerve, promoting neuronal stimuli to the solitary tract nucleus, signaling satiety. As a result, the long-term ingestion of a high-protein diet reduces not only food intake, but also body mass and body adiposity in rats. Conclusion: Supplementation with serum whey proteins at doses of 4 and 6 g/kg/day in sedentary animals conferred stability over total body weight and a significant reduction in feed intake over 12 weeks. Supplementation with serum whey proteins at 2 g/kg/day in sedentary animals did not lead to a reduction in the average feed intake and showed a similar effect to the other doses on total body weight