Pain suppression using non-steroidal anti-inflammatory drugs

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Pain Assessing meaningful changes and pre-emptive treatment

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Effects of pomegranate extract on blood flow and running time to exhaustion

Recent research has shown dietary nitrate to impart favorable effects on blood flow and exercise. The purpose of this randomized, double-blind, placebo-controlled, crossover study was to investigate the acute effects of pomegranate extract on blood flow, vessel diameter, and exercise performance in active individuals. Nineteen men and women (Mean ± SD; Age: 22.2 ± 2.2 yrs; Height: 174.8 ± 10.7 cm; Body mass: 71.9±13.5 kg) were randomly assigned to a placebo (PL) or pomegranate extract (PE) group. Participants performed a maximal oxygen consumption treadmill test to determine peak velocity (PV). Participants returned after 24–48 hours, and ingested either PL or PE. Brachial artery blood flow was assessed using ultrasound at baseline and 30 minutes post-ingestion (30minPI). Three treadmill runs to exhaustion (TTE) were performed at 90%, 100%, and 110%PV. Blood flow was assessed immediately after each exercise bout and 30 minutes post-exercise (30minPEx). After a 7–10 day washout, participants repeated the same procedures, ingesting the opposite supplement. Separate repeated measures ANOVAs were performed for blood flow, vessel diameter, and TTE. Blood flow was significantly augmented (p=0.033) 30minPI with PE in comparison to PL. Vessel diameter was significantly larger (p=0.036) 30minPEx with PE. Ingestion of the PE was found to significantly augment TTE at 90% (p=0.009) and 100% PV (p=0.027). Acute ingestion of PE 30 min prior to exercise may enhance vessel diameter, blood flow, and delay fatigue during exercise. Results of the current study indicate that PE is ergogenic for intermittent running, eliciting beneficial effects on blood flow

On the Intrinsic Fracture Pressure of Liquid and Solid Aluminum Around Its Melting Temperature

To determine the intrinsic fracture pressure of aluminum, data from studies that have used molecular dynamic simulations, the van der Waals method as well as experimental observations have been gathered and analyzed. Results indicate that aluminum has an intrinsic fracture pressure of − 4 GPa at its melting temperature in both liquid and solid states. Moreover, the Fisher equation can be used to estimate the intrinsic fracture pressure of liquid aluminum