224 research outputs found

    The Sociological Advantage

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    Abstract: To some, sociology is in a significant decline as a relevant social science. To others, the discipline provides a unique perspective of the interaction of social forces that define the role of race, class and gender. Through the development of useful theoretical propositions and pedagogical practices, the discipline can address its potential for social management and the application of sociological principles at the individual, group, organizational, and societal levels. By understanding intersectionality and the patterns or forms of social interaction, the informed sociologist can effectively practice, teach and apply the sociological advantage, possibly even five moves ahead

    Charles B.G. de Nancrede: Academic Surgeon at the Fin de Siècle

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/42409/1/268-22-11-1175_22n11p1175.pd

    Comparison of Histidine-Tryptophan-Ketoglutarate and University of Wisconsin Preservation in Renal Transplantation

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72258/1/j.1600-6143.2007.02065.x.pd

    Spontaneous rupture of renal pelvis after renal transplantation

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    Spontaneous rupture of the renal pelvis occurred in 4 cases following renal transplantation. The diagnosis was difficult, and all 4 patients were septic at the time of treatment. Three patients survived, but preservation of the transplant was possible in only 1 case. The cause is uncertain but may be related to functional obstruction or vascular insufficiency.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/24216/1/0000475.pd

    Inhibition of rat mixed lymphocyte cultures by suppressor macrophages

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    Normal rat spleens contain suppressor cells which can inhibit proliferative and cytotoxic responses of lymphocytes to alloantigens in vitro. The suppressor cells are adherent, phagocytic, resistant to treatment with ATS and C, radioresistant, resistant to treatment with mitomycin C, apparently absent from the thymus, and found in very high concentrations in peritoneal exudates. These characteristics indicate that the suppressor cell is a macrophages and not a T cell. When suppressor cells were removed from spleen cell suspensions, strong in vitro proliferative and cytotoxic responses to alloantigens could consistently be observed.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/22959/1/0000526.pd

    Species-dependent regulation of monocyte/macrophage Ia antigen expression and antigen presentation by prostaglandin E

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    The expression of Ia antigen by various murine and human macrophage populations and the ability of prostaglandins of the E series to regulate Ia antigen expression were explored. Monocytes and macrophages from human and murine populations demonstrated a dichotomy in the expression of Ia antigen. Both human monocytes and macrophages expressed elevated levels of Ia antigen compared to their murine counterpart. Murine macrophages appear to express elevated levels of Ia antigen only when actively interacting with T lymphocytes in vivo or with lymphokines in vitro. Prostaglandins of the E series can suppress murine macrophage Ia antigen expression, but have little effect on the expression of Ia antigen by human monocytes and macrophages. Also, prostaglandins of the E series do not modulate the ability of human monocytes to present antigen to autologous lymphocytes when studied over a broad concentration range. These data suggest that prostaglandin E compounds do not profoundly affect human monocyte/macrophage Ia antigen expression or human monocyte antigen presenting activity.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/26359/1/0000446.pd

    Building, scaling, and sustaining a learning health system for surgical quality improvement: A toolkit

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    This article describes how to start, replicate, scale, and sustain a learning health system for quality improvement, based on the experience of the Michigan Surgical Quality Collaborative (MSQC). The key components to operationalize a successful collaborative improvement infrastructure and the features of a learning health system are explained. This information is designed to guide others who desire to implement quality improvement interventions across a regional network of hospitals using a collaborative approach. A toolkit is provided (under Supporting Information) with practical information for implementation.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/156156/3/lrh210215.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/156156/2/lrh210215-sup-0001-supinfo.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/156156/1/lrh210215_am.pd

    Influence of breast feeding on subsequent reactivity to a related renal allograft

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    In a previous report the hypothesis that exposure of the neonate to maternal allogeneic cells via the process of breast feeding would result in hyporesponsiveness to a subsequent maternal donor-related renal transplant was examined. Support for this hypothesis was obtained after correlating results of maternal donor-related renal transplantation with the breast feeding status of the transplant recipient. In the present report this observation has been expanded upon and it was asked if a history of breast feeding was associated with improved results in a different patient population (HLA semi-identical sibling donors). Breast-fed patients showed dramatic improvements in graft function rates compared to non-breast-fed counterparts at all intervals studied (P [les] 0.001). Because a history of breast feeding correlated with improved results after sibling donor as well as maternal donor transplantation, it was concluded that the breast feeding effect is not entirely specific for maternal antigens. These observations underscore the importance of breast feeding as a variable in clinical-related renal transplantation.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/24730/1/0000152.pd
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