1,319 research outputs found
The association between seeking financial compensation and injury recovery following motor vehicle related orthopaedic trauma
© 2016 The Author(s). Background: Motor vehicle related moderate-severe orthopaedic trauma has a major impact on the burden of injury. In Australia, all states and territories provide access to financial compensation following injury in a motor vehicle crash. The aim of this study was to investigate the influence of seeking financial compensation (i.e., making a claim) on injury recovery following motor vehicle related moderate-severe orthopaedic trauma. Methods: Patients admitted with upper/lower extremity fractures after a motor vehicle crash were recruited from two trauma hospitals. Baseline data were collected in person by written questionnaire within two weeks of injury. Follow up data were collected by a mailed written questionnaire at six, 12 and 24 months. Additional (demographic/injury-related) information was collected from hospital databases, all other measures were self-reported. Outcomes were: Short Form-36 Version 2.0 (SF36v2), Physical/Mental Component Scores (PCS/MCS); Post Traumatic Stress Disorder (PTSD) Checklist Civilian Version (PCL-C); and Global Rating of Change (GRC) scale. Analysis involved descriptive statistics and linear mixed models to examine the effect of compensation status on injury recovery over time. Results: There were 452 study participants. Baseline characteristics showed: mean age 40 years (17.1 Standard Deviation [SD]); 75 % male; 74 % worked pre-injury; 67 % in excellent-very good pre-injury health; 56 % sustained serious injuries, Injury Severity Score (ISS) 9-15; 61 % had a low-middle range household income. Overall, after controlling for possible confounders, the compensable group had poorer recovery compared to the non-compensable group for PCS (-2.97 Mean Difference (MD), 95 % CI -4.73, -1.22); MCS (-3.44 MD, 95 % CI -5. 62, -1.26); PCL-C (3.42MD, 95 % CI 0.87, 5.99); and GRC (-0.66MD, 95 % CI -1.15, -0.17). Injury recovery over time for all participants showed: PCS improved from 6-12 and 12-24 months; MCS and GRC improved from 6-12 months; and PCL-C did not significantly improve from 6-12 and 12-24 months. Injury recovery over time continued for compensable and non-compensable groups but compensable participants had poorer scores at each time period, especially MCS and PCL-C. Conclusions: Making a claim was associated with poor injury recovery following motor vehicle related orthopaedic trauma, mainly for mental health. Irrespective of claim status, the majority had poor injury recovery, especially for mental health
Predictors of return to work following motor vehicle related orthopaedic trauma
© 2016 Murgatroyd et al. Background: Work disability following motor vehicle related orthopaedic trauma is a significant contributor to the burden of injury and disease. Early identification of predictors for return to work (RTW) is essential for developing effective interventions to prevent work disability. The study aim was to determine the predictors (including compensation related factors) of time to RTW following motor vehicle related orthopaedic trauma. Methods: Admitted patients were recruited prospectively from two trauma hospitals with upper and/or lower extremity fractures following a motor vehicle crash. Baseline and follow up data were collected by written questionnaire. For baseline, this occurred in person within 2 weeks of injury. For follow up, this occurred by mail at six, 12 and 24 months. Additional demographic and injury-related information was retrieved from hospital databases. Analysis involved: descriptive statistics; logrank test to detect survival distributions of categorical variables; and Cox proportional hazards regression models for risks of time to RTW using baseline characteristic and compensation related variables (at 6 months). Results: Of 452 study participants 334 (74 %) were working pre-injury: results are based on this subset. Baseline characteristics were mean age 36 years (13.9 Standard Deviation [SD]), 80 % male; 72 % self-assessed very good-excellent pre-injury health, 83 % household income > AU$40,000 (Australian Dollar). Follow up data was available for 233 (70 %), 210 (63 %), and 182 (54 %) participants at six, 12 and 24 months respectively. Significant risks of a longer time to RTW were greater injury severity, as measured by the New Injury Severity Score (NISS) (Hazards Rate Ratio [HRR] = 0.54, 95 % CI 0.35-0.82); and lower occupational skill levels (HRR = 0.53, 95 % CI 0.34-0.83). Significant risks of a shorter time to RTW were: recovery expectations for usual activities within 90 days (HRR = 2.10, 95 % CI 1.49-2.95); full-time pre-injury work hours (HRR = 1.99, 95 % CI 1.26-3.14); and very good self-assessed pre-injury health status (HRR = 1.41, 95 % CI 0.98-2.02). Legal representation (analysed at six months only) was not associated with time to RTW. At each time period, there were 146 (63 %), 149 (71 %), and 137 (76 %) working participants. Conclusions: A longer time to RTW was associated with greater injury severity and lower occupational skill levels; while a shorter time to RTW was associated with recovery expectations for usual activities within 90 days, full-time pre-injury work hours, and very good self-assessed pre-injury health status. Our findings reinforce existing research. There is an opportunity to trial interventions that address potentially modifiable factors. The issues surrounding legal representation are complex and require further research
Probable detection of starlight reflected from the giant exoplanet orbiting tau Bootis
Giant planets orbiting stars other than the Sun are clearly detectable
through precise radial-velocity measurements of the orbital reflex motion of
the parent star. In the four years since the discovery of the companion to the
star 51 Peg, similar low-amplitude ``Doppler star wobbles'' have revealed the
presence of some 20 planets orbiting nearby solar-type stars. Several of these
newly-discovered planets are very close to their parent stars, in orbits with
periods of only a few days. Being an indirect technique, however, the
reflex-velocity method has little to say about the sizes or compositions of the
planets, and can only place lower limits on their masses. Here we report the
use of high-resolution optical spectroscopy to achieve a probable detection of
the Doppler-shifted signature of starlight reflected from one of these objects,
the giant exoplanet orbiting the star tau Bootis. Our data give the planet's
orbital inclination i=29 degrees, indicating that its mass is some 8 times that
of Jupiter, and suggest strongly that the planet has the size and reflectivity
expected for a gas-giant planet.Comment: 15 pages, 4 figures. (Fig 1 and equation for epsilon on p1 para 2
revised; changed from double to single spacing
A study of 54 cases of left displacement of the abomasum: February to July 2005
Fifty-four cows with left displacement of the abomasum (LDA) submitted to the hospital facility at Riverview Veterinary Clinic from February to July 2005 were treated by right flank laparotomy and omentopexy. Five cows died (a survival rate 90.7%) and one cow (1.8%) was culled due to recurrence of the LDA post-operatively. Forty-one cows (76%) returned to good production post-operatively. Thirty-nine cows (72%) were pregnant six months after corrective surgery
Cortactin and phagocytosis in isolated Sertoli cells
BACKGROUND: Cortactin, an actin binding protein, has been associated with Sertoli cell ectoplasmic specializations in vivo, based on its immunolocalization around the heads of elongated spermatids, but not previously identified in isolated Sertoli cells. In an in vitro model of Sertoli cell-spermatid binding, cortactin was identified around debris and dead germ cells. Based on this observation, we hypothesized that this actin binding protein may be associated with a non-junction-related physiological function, such as phagocytosis. The purpose of this study was to identify the presence and distribution of cortactin in isolated rat Sertoli cells active in phagocytic activity following the addition of 0.8 μm latex beads. RESULTS: Sertoli cell monocultures were incubated with or without follicle stimulating hormone (FSH; 0.1 μg/ml) in the presence or absence of cytochalasin D (2 μM), as an actin disrupter. Cortactin was identified by standard immunostaining with anti-cortactin, clone 4F11 (Upstate) after incubation times of 15 min, 2 hr, and 24 hr with or without beads. Cells exposed to no hormone and no beads appeared to have a ubiquitous distribution of cortactin throughout the cytoplasm. In the presence of cytochalasin D, cortactin immunostaining was punctate and distributed in a pattern similar to that reported for actin in cells exposed to cytochalasin D. Sertoli cells not exposed to FSH, but activated with beads, did not show cortactin immunostaining around the phagocytized beads at any of the time periods. FSH exposure did not alter the distribution of cortactin within Sertoli cells, even when phagocytic activity was upregulated by the presence of beads. CONCLUSION: Results of this study suggest cortactin is not associated with peripheralized actin at junctional or phagocytic sites. Further studies are necessary to clarify the role of cortactin in Sertoli cells
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Long-term stellar activity variations and their effect on radial-velocity measurements
Long-term stellar activity variations can affect the detectability of
long-period and Earth-analogue extrasolar planets. We have, for 54 stars,
analysed the long-term trend of five activity indicators:
log, the cross-correlation function (CCF) bisector span, CCF
full-width-at-half-maximum, CCF contrast, and the area of the Gaussian fit to
the CCF; and studied their correlation with the RVs. The sign of the
correlations appears to vary as a function of stellar spectral type, and the
transition in sign signals a noteworthy change in the stellar activity
properties where earlier type stars appear more plage dominated. These
transitions become more clearly defined when considered as a function of the
convective zone depth. Therefore, it is the convective zone depth (which can be
altered by stellar metallicity) that appears to be the underlying fundamental
parameter driving the observed activity correlations. In addition, for most of
the stars, we find that the RVs become increasingly red-shifted as activity
levels increase, which can be explained by the increase in the suppression of
convective blue-shift. However, we also find a minority of stars where the RVs
become increasingly blue-shifted as activity levels increase. Finally, using
the correlation found between activity indicators and RVs, we removed RV
signals generated by long-term changes in stellar activity. We find that
performing simple cleaning of such long-term signals enables improved planet
detection at longer orbital periods
Estimating magnetic filling factors from simultaneous spectroscopy and photometry : disentangling spots, plage, and network
A.C.C. acknowledges support from the Science and Technology Facilities Council (STFC) consolidated grant number ST/R000824/1.State-of-the-art radial velocity (RV) exoplanet searches are limited by the effects of stellar magnetic activity. Magnetically active spots, plage, and network regions each have different impacts on the observed spectral lines and therefore on the apparent stellar RV. Differentiating the relative coverage, or filling factors, of these active regions is thus necessary to differentiate between activity-driven RV signatures and Doppler shifts due to planetary orbits. In this work, we develop a technique to estimate feature-specific magnetic filling factors on stellar targets using only spectroscopic and photometric observations. We demonstrate linear and neural network implementations of our technique using observations from the solar telescope at HARPS-N, the HK Project at the Mt. Wilson Observatory, and the Total Irradiance Monitor onboard SORCE. We then compare the results of each technique to direct observations by the Solar Dynamics Observatory. Both implementations yield filling factor estimates that are highly correlated with the observed values. Modeling the solar RVs using these filling factors reproduces the expected contributions of the suppression of convective blueshift and rotational imbalance due to brightness inhomogeneities. Both implementations of this technique reduce the overall activity-driven rms RVs from 1.64 to 1.02 m s(-1), corresponding to a 1.28 m s(-1) reduction in the rms variation. The technique provides an additional 0.41 m s(-1) reduction in the rms variation compared to traditional activity indicators.PostprintPeer reviewe
Rotation of planet-harbouring stars
The rotation rate of a star has important implications for the detectability,
characterisation and stability of any planets that may be orbiting it. This
chapter gives a brief overview of stellar rotation before describing the
methods used to measure the rotation periods of planet host stars, the factors
affecting the evolution of a star's rotation rate, stellar age estimates based
on rotation, and an overview of the observed trends in the rotation properties
of stars with planets.Comment: 16 pages, 4 figures: Invited review to appear in 'Handbook of
Exoplanets', Springer Reference Works, edited by Hans J. Deeg and Juan
Antonio Belmont
"A convenient truth": air travel passengers' willingness to pay to offset their CO2 emissions
Several economic reviews demonstrate the substantial costs related to climate
change and consequently call for early action. These reviews, however, have been limited
to measuring ‘objective’ risks and expected material damage related to climate change. The
‘subjective’ perceived risk of climate change and society’s willingness to pay (WTP) to
avoid these risks are expected to provide an important additional motivation for direct
action. We investigate whether and why air travel passengers—an increasingly important
source of greenhouse gas emissions—are supportive of measures that increase the cost of
their travel based on the polluter pays principle and compensate the damage caused by their
flight. Compared to the results of the few previous studies that have elicited WTP estimates
for climate policy more generally, our results appear to be at the lower end of the scale,
while a comparison to estimates of the social cost of carbon shows that the average WTP
estimate in this study is close to the estimated marginal damage cost. Although significant
differences are found between travellers from Europe, North America, Asia and the rest of
the world, we show that there exists a substantial demand for climate change mitigation
action. The positive risk premium over and above the expected property damage cost
assessments should be accounted for more explicitly in economic reviews as it will add to
the burden of proof of direct action. Measurements of passenger WTP will help policy
makers to design effective financial instruments aimed at discouraging climate-unfriendly
travel activities as well as to generate funds for the measures directed at climate change
mitigation and adaptation. Based on stated WTP by travellers to offset their greenhouse gas
emissions, funds in the order of magnitude of €23 billion could be generated annually to
finance climate change mitigation activities
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