53 research outputs found

    The role of Tadalafil in the treatment of benign prostatic hyperplasia and erectile dysfunction

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    The aim of this study is to investigate the effectiveness of a single 5 mg daily dose of Tadalafil in patients with lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) accompanied by erectile dysfunction (ED). The data of patients who applied to the urology outpatient clinic between 2014 and 2019 and were diagnosed with BPH and ED were retrospectively analysed. Before and after the treatment with 5 mg tadalafil daily for 12 weeks; maximum flow rate (Qmax), average flow rate (Qave), postvoid residual volume (PVR), prostate volume (PV), PSA values, IPSS and IIEF scores of the patients were compared. The mean age of 66 male patients diagnosed with ED and BPH was 48.1±6.9 years. The mean IPSS score of the patients before the treatment was 9.85 which represents moderate LUTS. After the treatment, the mean score decreased to 5.7 which represents mild LUTS. Before the treatment, the mean IIEF score showed mild ED with 18.79. After the treatment, the mean IIEF score increased to 29,9. The treatment statistically significantly decreased ED and increased the IIEF score (p=0.000). While the mean Qmax and Qave were increased statistically significantly (p=0.000). A statistically significant decrease was observed in the mean PVR from 60.1 ml to 37.6 ml (p=0.000). The decrease in PV was not statistically significant (p=0.321). The decrease in PSA values before and after treatment was found to be statistically significant with p=0.046. It has been shown that the daily use of 5 mg Tadalafil alone for 12 weeks can be a preferable treatment option, especially in younger patients with BPH / LUTS and ED

    Estimating the prevalence of functional exonic splice regulatory information

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    Pamukkale University)

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    Emerged in the second half of the 20th century, conceptual art is an understanding of art which questions the relationship of art with the conveying object, features its intellectual aspect rather than mere aesthetic pleasure, and contains different and eclectic compositions. The purpose of the current study is to identify the views of visual arts teacher candidates studying at Pamukkale University on conceptual arts. In this sense, convenience purposive sampling within qualitative research was used. As for the data gathering instrument, an open-ended question form was used in order for students to express their views in writing. The questions were finalized through expert opinion of three faculty members in the area. 47 students studying at 4th year answered the questions. The answers were analysed through descriptive content analysis and themes and concept codes were identified. The findings were then interpreted by the researchers. In the results section, various conclusions were drawn. (C) 2015 Published by Elsevier Ltd

    Mean field approach to the correlation effects on the density of electronic states and conductivity of disordered metals

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    Effects of correlation in weakly disordered systems on the density of electronic states (DOS) and the conductivity are examined in the framework of the mean field approach. As a result of the approximation, the electronic energy spectrum is changed from a free electron energy spectrum to a Hartree exchange term added energy spectrum form. Coulomb interaction is shown to give a correction to the DOS, which reduces the electronic states. Calculations of the conductivity show that, although Coulomb interaction evaluated by the mean field theory decreases the Drude conductivity, it acts as a dephasing factor for the quantum localization correction to the conductivity
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