Unary FA-presentable semigroups

Automatic presentations, also called FA-presentations, were introduced to extend nite model theory to innite structures whilst retaining the solubility of interesting decision problems. A particular focus of research has been the classication of those structures of some species that admit automatic presentations. Whilst some successes have been obtained, this appears to be a dicult problem in general. A restricted problem, also of signicant interest, is to ask this question for unary automatic presentations: auto-matic presentations over a one-letter alphabet. This paper studies unary FA-presentable semigroups. We prove the following: Every unary FA-presentable structure admits an injective unary automatic presentation where the language of representatives consists of every word over a one-letter alphabet. Unary FA-presentable semigroups are locally nite, but non-nitely generated unary FA-presentable semigroups may be innite. Every unary FA-presentable semigroup satises some Burnside identity.We describe the Green's relations in unary FA-presentable semigroups. We investigate the relationship between the class of unary FA-presentable semigroups and various semigroup constructions. A classication is given of the unary FA-presentable completely simple semigroups.PostprintPeer reviewe

Automatic presentations for semigroups

Special Issue: 2nd International Conference on Language and Automata Theory and Applications (LATA 2008)This paper applies the concept of FA-presentable structures to semigroups. We give a complete classification of the finitely generated FA-presentable cancellative semigroups: namely, a finitely generated cancellative semigroup is FA-presentable if and only if it is a subsemigroup of a virtually abelian group. We prove that all finitely generated commutative semigroups are FA-presentable. We give a complete list of FA-presentable one-relation semigroups and compare the classes of FA-presentable semigroups and automatic semigroups. (C) 2009 Elsevier Inc. All rights reserved.PostprintPeer reviewe

Decision problems for word-hyperbolic semigroups

This paper studies decision problems for semigroups that are word-hyperbolic in the sense of Duncan & Gilman. A fundamental investigation reveals that the natural definition of a `word-hyperbolic structure' has to be strengthened slightly in order to define a unique semigroup up to isomorphism. The isomorphism problem is proven to be undecidable for word-hyperbolic semigroups (in contrast to the situation for word-hyperbolic groups). It is proved that it is undecidable whether a word-hyperbolic semigroup is automatic, asynchronously automatic, biautomatic, or asynchronously biautomatic. (These properties do not hold in general for word-hyperbolic semigroups.) It is proved that the uniform word problem for word-hyperbolic semigroup is solvable in polynomial time (improving on the previous exponential-time algorithm). Algorithms are presented for deciding whether a word-hyperbolic semigroup is a monoid, a group, a completely simple semigroup, a Clifford semigroup, or a free semigroup.PostprintPeer reviewe

Presentations for subsemigroups of groups

This thesis studies subsemigroups of groups from three perspectives: automatic structures, ordinary semigroup presentations, and Malcev presentaions. [A Malcev presentation is a presentation of a special type for a semigroup that can be embedded into a group. A group-embeddable semigroup is Malcev coherent if all of its finitely generated subsemigroups admit finite Malcev presentations.] The theory of synchronous and asynchronous automatic structures for semigroups is expounded, particularly for group-embeddable semigroups. In particular, automatic semigroups embeddable into groups are shown to inherit many of the pleasant geometric properties of automatic groups. It is proved that group- embeddable automatic semigroups admit finite Malcev presentations, and such presentations can be found effectively. An algorithm is exhibited to test whether an automatic semigroup is a free semigroup. Cancellativity of automatic semigroups is proved to be undecidable. Study is made of several classes of groups: virtually free groups; groups that satisfy semigroup laws (in particular [virtually] nilpotent and [virtually] abelian groups); polycyclic groups; free and direct products of certain groups; and one-relator groups. For each of these classes, the question of Malcev coherence is considered, together with the problems of whether finitely generated subsemigroups are finitely presented or automatic. This study yields closure and containment results regarding the class of Malcev coherent groups. The property of having a finite Malcev presentation is shown to be preserved under finite Rees index extensions and subsemigroups. Other concepts of index are also studied

eLoanDocs: Riding the Tide of Technology Without Wiping Out

This teaching case describes how eLoanDocs, a professional services business serving the mortgage loan industry, recognized the benefits of emerging technologies to reduce costs and improve process throughput to establish a competitive position in its in marketplace. The case documents how the company adapted to changes in the technological landscape over the past two decades and presents the reader with the decisions the company now faces with the evolution of “cloud computing”. The case gives students a fundamental understanding of the concept of cloud computing and presents the advantages and risks of this IT infrastructure

Extrinsic Rewards and Intrinsic Motives: Standard and Behavioral Approaches to Agency and Labor Markets

Employers structure pay and employment relationships to mitigate agency problems. A large literature in economics documents how the resolution of these problems shapes personnel policies and labor markets. For the most part, the study of agency in employment relationships relies on highly stylized assumptions regarding human motivation, e.g., that employees seek to earn as much money as possible with minimal effort. In this essay, we explore the consequences of introducing behavioral complexity and realism into models of agency within organizations. Specifically, we assess the insights gained by allowing employees to be guided by such motivations as the desire to compare favorably to others, the aspiration to contribute to intrinsically worthwhile goals, and the inclination to reciprocate generosity or exact retribution for perceived wrongs. More provocatively, from the standpoint of standard economics, we also consider the possibility that people are driven, in ways that may be opaque even to themselves, by the desire to earn social esteem or to shape and reinforce identity

The impact of immediate breast reconstruction on the time to delivery of adjuvant therapy: the iBRA-2 study

Background: Immediate breast reconstruction (IBR) is routinely offered to improve quality-of-life for women requiring mastectomy, but there are concerns that more complex surgery may delay adjuvant oncological treatments and compromise long-term outcomes. High-quality evidence is lacking. The iBRA-2 study aimed to investigate the impact of IBR on time to adjuvant therapy. Methods: Consecutive women undergoing mastectomy ± IBR for breast cancer July–December, 2016 were included. Patient demographics, operative, oncological and complication data were collected. Time from last definitive cancer surgery to first adjuvant treatment for patients undergoing mastectomy ± IBR were compared and risk factors associated with delays explored. Results: A total of 2540 patients were recruited from 76 centres; 1008 (39.7%) underwent IBR (implant-only [n = 675, 26.6%]; pedicled flaps [n = 105,4.1%] and free-flaps [n = 228, 8.9%]). Complications requiring re-admission or re-operation were significantly more common in patients undergoing IBR than those receiving mastectomy. Adjuvant chemotherapy or radiotherapy was required by 1235 (48.6%) patients. No clinically significant differences were seen in time to adjuvant therapy between patient groups but major complications irrespective of surgery received were significantly associated with treatment delays. Conclusions: IBR does not result in clinically significant delays to adjuvant therapy, but post-operative complications are associated with treatment delays. Strategies to minimise complications, including careful patient selection, are required to improve outcomes for patients

Class, Youth and Dirty Jobs: The Working-Class and Post-War Britain in Pete Townshend's Quadrophenia

FOS

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.

Importance: Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19) is limited. Objective: To determine whether hydrocortisone improves outcome for patients with severe COVID-19. Design, Setting, and Participants: An ongoing adaptive platform trial testing multiple interventions within multiple therapeutic domains, for example, antiviral agents, corticosteroids, or immunoglobulin. Between March 9 and June 17, 2020, 614 adult patients with suspected or confirmed COVID-19 were enrolled and randomized within at least 1 domain following admission to an intensive care unit (ICU) for respiratory or cardiovascular organ support at 121 sites in 8 countries. Of these, 403 were randomized to open-label interventions within the corticosteroid domain. The domain was halted after results from another trial were released. Follow-up ended August 12, 2020. Interventions: The corticosteroid domain randomized participants to a fixed 7-day course of intravenous hydrocortisone (50 mg or 100 mg every 6 hours) (n = 143), a shock-dependent course (50 mg every 6 hours when shock was clinically evident) (n = 152), or no hydrocortisone (n = 108). Main Outcomes and Measures: The primary end point was organ support-free days (days alive and free of ICU-based respiratory or cardiovascular support) within 21 days, where patients who died were assigned -1 day. The primary analysis was a bayesian cumulative logistic model that included all patients enrolled with severe COVID-19, adjusting for age, sex, site, region, time, assignment to interventions within other domains, and domain and intervention eligibility. Superiority was defined as the posterior probability of an odds ratio greater than 1 (threshold for trial conclusion of superiority >99%). Results: After excluding 19 participants who withdrew consent, there were 384 patients (mean age, 60 years; 29% female) randomized to the fixed-dose (n = 137), shock-dependent (n = 146), and no (n = 101) hydrocortisone groups; 379 (99%) completed the study and were included in the analysis. The mean age for the 3 groups ranged between 59.5 and 60.4 years; most patients were male (range, 70.6%-71.5%); mean body mass index ranged between 29.7 and 30.9; and patients receiving mechanical ventilation ranged between 50.0% and 63.5%. For the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively, the median organ support-free days were 0 (IQR, -1 to 15), 0 (IQR, -1 to 13), and 0 (-1 to 11) days (composed of 30%, 26%, and 33% mortality rates and 11.5, 9.5, and 6 median organ support-free days among survivors). The median adjusted odds ratio and bayesian probability of superiority were 1.43 (95% credible interval, 0.91-2.27) and 93% for fixed-dose hydrocortisone, respectively, and were 1.22 (95% credible interval, 0.76-1.94) and 80% for shock-dependent hydrocortisone compared with no hydrocortisone. Serious adverse events were reported in 4 (3%), 5 (3%), and 1 (1%) patients in the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively. Conclusions and Relevance: Among patients with severe COVID-19, treatment with a 7-day fixed-dose course of hydrocortisone or shock-dependent dosing of hydrocortisone, compared with no hydrocortisone, resulted in 93% and 80% probabilities of superiority with regard to the odds of improvement in organ support-free days within 21 days. However, the trial was stopped early and no treatment strategy met prespecified criteria for statistical superiority, precluding definitive conclusions. Trial Registration: ClinicalTrials.gov Identifier: NCT02735707