31,075 research outputs found
Testing the Lorentz and CPT Symmetry with CMB polarizations and a non-relativistic Maxwell Theory
We present a model for a system involving a photon gauge field and a scalar
field at quantum criticality in the frame of a Lifthitz-type non-relativistic
Maxwell theory. We will show this model gives rise to Lorentz and CPT violation
which leads to a frequency-dependent rotation of polarization plane of
radiations, and so leaves potential signals on the cosmic microwave background
temperature and polarization anisotropies.Comment: 7 pages, 2 figures, accepted on JCAP, a few references adde
Behavior of Cold-formed Stainless Steel Single Shear Bolted Connections at Elevated Temperatures
postprin
Heterodimerization of apelin receptor and neurotensin receptor 1 induces phosphorylation of ERK1/2 and cell proliferation via Gαq-mediated mechanism
Dimerization of G protein-coupled receptors (GPCRs) is crucial for receptor function including agonist affinity, efficacy, trafficking and specificity of signal transduction, including G protein coupling. Emerging data suggest that the cardiovascular system is the main target of apelin, which exerts an overall neuroprotective role, and is a positive regulator of angiotensin-converting enzyme 2 (ACE2) in heart failure. Moreover, ACE2 cleaves off C-terminal residues of vasoactive peptides including apelin-13, and neurotensin that activate the apelin receptor (APJ) and neurotensin receptor 1 (NTSR1) respectively, that belong to the A class of GPCRs. Therefore, based on the similar mode of modification by ACE2 at peptide level, the homology at amino acid level and the capability of forming dimers with other GPCRs, we have been suggested that APJ and NTSR1 can form a functional heterodimer. Using co-immunoprecipitation, BRET and FRET, we provided conclusive evidence of heterodimerization between APJ and NTSR1 in a constitutive and induced form. Upon agonist stimulation, hetrodimerization enhanced ERK1/2 activation and increased proliferation via activation of Gq α-subunits. These novel data provide evidence for a physiological role of APJ/NTSR1 heterodimers in terms of ERK1/2 activation and increased intracellular calcium and induced cell proliferation and provide potential new pharmaceutical targets for cardiovascular disease. © 2014 The Authors
Probing and modelling the localized self-mixing in a GaN/AlGaN field-effect terahertz detector
In a GaN/AlGaN field-effect terahertz detector, the directional photocurrent
is mapped in the two-dimensional space of the gate voltage and the drain/source
bias. It is found that not only the magnitude, but also the polarity, of the
photocurrent can be tuned. A quasistatic self-mixing model taking into account
the localized terahertz field provides a quantitative description of the
detector characteristics. Strongly localized self-mixing is confirmed. It is
therefore important to engineer the spatial distribution of the terahertz field
and its coupling to the field-effect channel on the sub-micron scale.Comment: 12 pages, 4 figures, submitted to AP
Analyzing Energy Efficiency for IoT Devices with DRX Capability and Poisson Arrivals
Energy-efficient communications is one important consideration for Internet of Things (IoT) devices, and it can be achieved via the discontinuous reception (DRX) technology. In this paper, we consider an IoT device with the DRX capability. The device is functioning based on the LTE standard and it is communicating with the base station over a Nakagami- m fading channel. Data are generated with fixed length and Poisson processes. Under these settings, we develop a cross-layer analytical model to analyze 1) the energy efficiency, 2) stationary probability and 3) state holding time of this device. Simulation results show that the proposed model can approximate the three performance of a IoT device accurately
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