Synthetic Quantum Systems

So far proposed quantum computers use fragile and environmentally sensitive natural quantum systems. Here we explore the new notion that synthetic quantum systems suitable for quantum computation may be fabricated from smart nanostructures using topological excitations of a stochastic neural-type network that can mimic natural quantum systems. These developments are a technological application of process physics which is an information theory of reality in which space and quantum phenomena are emergent, and so indicates the deep origins of quantum phenomena. Analogous complex stochastic dynamical systems have recently been proposed within neurobiology to deal with the emergent complexity of biosystems, particularly the biodynamics of higher brain function. The reasons for analogous discoveries in fundamental physics and neurobiology are discussed.Comment: 16 pages, Latex, 1 eps figure fil

Letter from Dr. E. B. Cahill, 1913-08-09, Mountain View, M.E., to Anne Whitney, Shelburne, N.H.

https://repository.wellesley.edu/whitney_correspondence/2499/thumbnail.jp

Letter from Dr. E. B. Cahill, 1913-08-04, Mountain View, M.E., to Anne Whitney, Shelburne, N.H.

https://repository.wellesley.edu/whitney_correspondence/2498/thumbnail.jp

Letter from Dr. E. B. Cahill, 1914-06-30, Boston, Mass., to Anne Whitney, Plymouth, Mass.

https://repository.wellesley.edu/whitney_correspondence/2501/thumbnail.jp

Letter from Dr. E. B. Cahill, Boston, Massachusetts, to Anne Whitney, Shelburne, New Hampshire, 1912 July 25

https://repository.wellesley.edu/whitney_correspondence/2492/thumbnail.jp

Letter from Dr. E. B. Cahill, 1914-07-10, Boston, Mass., to Anne Whitney, Plymouth, Mass.

https://repository.wellesley.edu/whitney_correspondence/2502/thumbnail.jp

Molecular Electroporation and the Transduction of Oligoarginines

Certain short polycations, such as TAT and polyarginine, rapidly pass through the plasma membranes of mammalian cells by an unknown mechanism called transduction as well as by endocytosis and macropinocytosis. These cell-penetrating peptides (CPPs) promise to be medically useful when fused to biologically active peptides. I offer a simple model in which one or more CPPs and the phosphatidylserines of the inner leaflet form a kind of capacitor with a voltage in excess of 180 mV, high enough to create a molecular electropore. The model is consistent with an empirical upper limit on the cargo peptide of 40--60 amino acids and with experimental data on how the transduction of a polyarginine-fluorophore into mouse C2C12 myoblasts depends on the number of arginines in the CPP and on the CPP concentration. The model makes three testable predictions.Comment: 15 pages, 5 figure

Letter from Dr. E. B. Cahill, Boston, Massachusetts, to Anne Whitney, Shelburne, New Hampshire, 1912 August 29

https://repository.wellesley.edu/whitney_correspondence/2493/thumbnail.jp

Letter from Dr. E. B. Cahill, Boston, Massachusetts, to Anne Whitney, 1913 July 10

https://repository.wellesley.edu/whitney_correspondence/2495/thumbnail.jp

Letter from Dr. E. B. Cahill, 1914-07-27, Boston, Mass., to Anne Whitney, Plymouth, Mass.

https://repository.wellesley.edu/whitney_correspondence/2503/thumbnail.jp