11 research outputs found
Caracterização da transmissĂŁo do vĂrus do mosaico-das-nervuras do algodoeiro pelo pulgĂŁo Aphis gossyphii com relação Ă persistĂȘncia e ao tempo necessĂĄrio para inoculação
NĂveis nutricionais de treonina digestĂvel para poedeiras leves no segundo ciclo de produção
Desempenho e qualidade dos ovos de poedeiras comerciais alimentadas com raçÔes contendo diferentes nĂveis de metionina e lisina
Desempenho, qualidade dos ovos e balanço de nitrogĂȘnio de poedeiras comerciais alimentadas com raçÔes contendo diferentes nĂveis de proteĂna bruta e lisina
ExigĂȘncia nutricional de lisina digestĂvel para galinhas poedeiras leves em produção
NĂveis de lisina digestĂvel e zinco quelato sobre os parĂąmetros produtivos de poedeiras marrons
Reduced fronto-striatal volume in attention-deficit/hyperactivity disorder in two cohorts across the lifespan
Attention-Deficit/Hyperactivity Disorder (ADHD) has been associated with altered brain anatomy in neuroimaging studies. However, small and heterogeneous study samples, and the use of region-of-interest and tissue-specific analyses have limited the consistency and replicability of these effects. We used a data-driven multivariate approach to investigate neuroanatomical features associated with ADHD in two independent cohorts: the Dutch NeuroIMAGE cohort (n = 890, 17.2 years) and the Brazilian IMpACT cohort (n = 180, 44.2 years). Using independent component analysis of whole-brain morphometry images, 375 neuroanatomical components were assessed for association with ADHD. In both discovery (corrected-p = 0.0085) and replication (p = 0.032) cohorts, ADHD was associated with reduced volume in frontal lobes, striatum, and their interconnecting white-matter. Current results provide further evidence for the role of the fronto-striatal circuit in ADHD in children, and for the first time show its relevance to ADHD in adults. The fact that the cohorts are from different continents and comprise different age ranges highlights the robustness of the findings