166 research outputs found

    ND266: A New Parental Line for Improved Corn Hybrids

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    The article discusses the need for a new ?parental? line for the improvement of corn hybrids. Future genetic improvement in corn hybrids in North Dakota was dependent upon the availability of improved, parental inbred lines for use in corn, hybrid research and production. Single Cross hybrids were concluded to be more productive than synthetic hybrids and open pollinated varieties of corn. ND266 was the latest inbred line developed in this eighth generation self-pollinated line, a synthetic developed at NDSU

    Response of parametrically-driven nonlinear coupled oscillators with application to micro- and nanomechanical resonator arrays

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    The response of a coupled array of nonlinear oscillators to parametric excitation is calculated in the weak nonlinear limit using secular perturbation theory. Exact results for small arrays of oscillators are used to guide the analysis of the numerical integration of the model equations of motion for large arrays. The results provide a qualitative explanation for a recent experiment [Buks and Roukes, cond-mat/0008211, to appear in J. MEMS (2002)] involving a parametrically-excited micromechanical resonator array. Future experiments are suggested that could provide quantitative tests of the theoretical predictions.Comment: 27 pages (in preprint format), 8 figure

    Hydrodynamics of thermal granular convection

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    A hydrodynamic theory is formulated for buoyancy-driven ("thermal") granular convection, recently predicted in molecular dynamic simulations and observed in experiment. The limit of a dilute flow is considered. The problem is fully described by three scaled parameters. The convection occurs via a supercritical bifurcation, the inelasticity of the collisions being the control parameter. The theory is expected to be valid for small Knudsen numbers and nearly elastic grain collisions.Comment: 4 pages, 4 EPS figures, some details adde

    The UKIDSS Galactic Plane Survey

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    'The definitive version is available at www.blackwell-synergy.com .' Copyright Blackwell Publishing DOI: 10.1111/j.1365-2966.2008.13924.xThe UKIDSS Galactic Plane Survey (GPS) is one of the five near-infrared Public Legacy Surveys that are being undertaken by the UKIDSS consortium, using the Wide Field Camera on the United Kingdom Infrared TelescopePeer reviewe

    Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

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    A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 mutation carriers and 73,444 controls and identify 13 candidate causal SNPs associated with serous OC (P=9.2 × 10-20), ER-negative BC (P=1.1 × 10-13), BRCA1-associated BC (P=7.7 × 10-16) and triple negative BC (P-diff=2 × 10-5). Genotype-gene expression associations are identified for candidate target genes ANKLE1 (P=2 × 10-3) and ABHD8 (P<2 × 10-3). Chromosome conformation capture identifies interactions between four candidate SNPs and ABHD8, and luciferase assays indicate six risk alleles increased transactivation of the ADHD8 promoter. Targeted deletion of a region containing risk SNP rs56069439 in a putative enhancer induces ANKLE1 downregulation; and mRNA stability assays indicate functional effects for an ANKLE1 3′-UTR SNP. Altogether, these data suggest that multiple SNPs at 19p13 regulate ABHD8 and perhaps ANKLE1 expression, and indicate common mechanisms underlying breast and ovarian cancer risk
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