19 research outputs found
Surface photochemical modification of TiO2 nanotube/Ti plates for photocatalytic elimination of methylene orange dye
Hydrothermal synthesis of TiO2 hollow spheres adorned with SnO2 quantum dots and their efficiency in the production of methanol via photocatalysis
Hydrothermal fabrication of WO3-modified TiO2 crystals and their efficiency in photocatalytic degradation of FCF
Ultrasonic-assisted synthesis of ZnO/NiO nanocomposites and kinetic study of their photocatalytic activity
Photosensitization of TiO2 nanofibers by Ag2S with the synergistic effect of excess surface Ti3+ states for enhanced photocatalytic activity under simulated sunlight
A single step unique microstructural growth of porous colossal dielectric constant titanium oxide
Technology Insight: small, noncoding RNA molecules as tools to study and treat endocrine diseases
The capacity of tiny, noncoding RNA molecules (including small, interfering RNA molecules and micro-RNA molecules [miRNAs]) to control gene expression in a very specific and efficient manner has opened new avenues in biomedical research. RNA interference (RNAi) is now an important tool able to specifically inhibit the expression of almost any gene. The understanding of the molecular determinants of endocrine diseases has benefited a great deal from the new opportunities offered by the use of RNAi. Because RNAi is able to specifically inhibit the expression of particular genes it has great therapeutic potential, and the first clinical trials have already started. The delivery of RNAi in vivo, however, requires different methods to those used in vitro. RNAi uses several components of a cellular pathway devoted to the production of miRNAs, a class of naturally occurring small, noncoding RNA molecules that function as translational repressors. There is growing evidence that miRNAs play key regulatory roles in several cellular processes, such as proliferation, differentiation and apoptosis, and recent publications have demonstrated that alterations in miRNA function might be involved in endocrine diseases, including diabetes mellitus, and in endocrine cancer