25 research outputs found

    Stypandrol and stypandra toxicosis

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    Scorazanone, a 1-aza-anthraquinone from Goniothalamus scortechinii

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    The air dried roots of Goniothalamus scortechinii, collected in Malaysia, yielded a new 1 -aza-anthraquinone, scorazanone, which was identified using spectroscopic techniques

    Identification of galegine, an isoprenyl guanidine, as the toxic principle of Schoenus asperocarpus (poison sedge)

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    An Isoprenyl guanldine, galegine, was isolated from the Western Australian sedge Schoenus asperocarpus (Cyperaceae). Synthetic galegine was shown to reproduce the clinical and pathological features of poisoning by this plant. Preliminary results suggest that the massive thoracic effusion observed in sedge poisoning is the result of a direct effect on pulmonary vascular permeability

    Stypandrone: A toxic naphthalene-14-quinone from Stypandra imbricata and Dianella revoluta

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    A compound, previously not isolated from dried, milled samples of Stypandra imbricata and Dianella revoluta, has now been obtained from fresh samples of these plants. The structure was shown, by spectroscopic techniques, to be identical to that of stypandrone. This quinone was found to be toxic to laboratory mice. However, it produces a different toxic effect to that observed when livestock ingest fresh Stypandra imbricata or when stypandrol is administered to laboratory mice

    Dianellidin, stypandrol and dianellinone: An oxidation-related series from dianella revoluta

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    Dianellidin, stypandrol and dianellinone were isolated from Dianella revoluta and were considered with respect to their biosynthetic relationship and to the toxicity of Stypandra imbricata

    Tepanone, a retrochalcone from Ellipeia cuneifolia

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    Tepanone, (2E)-1-phenyl-3-(2-hydroxy-3,4,6-trimethoxyphenyl)prop-2-enone was isolated from roots and stembark of Ellipeia cuneifolia. The structure was deduced from spectroscopic data and confirmed by synthesis of the methylated derivative, methyltepanone. Methyltepanone exists as the two readily interconvertible trans and cis isomers
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