High-yield neutral sulfite pulps

Information reviewed and reaffirmed 1962. Original report issued March 1956

Hypervirulent Clostridium difficile PCR-Ribotypes Exhibit Resistance to Widely Used Disinfectants

The increased prevalence of Clostridium difficile infection (CDI) has coincided with enhanced transmissibility and severity of disease, which is often linked to two distinct clonal lineages designated PCR-ribotype 027 and 017 responsible for CDI outbreaks in the USA, Europe and Asia. We assessed sporulation and susceptibility of three PCR-ribotypes; 012, 017 and 027 to four classes of disinfectants; chlorine releasing agents (CRAs), peroxygens, quaternary ammonium compounds (QAC) and biguanides. The 017 PCR-ribotype, showed the highest sporulation frequency under these test conditions. The oxidizing biocides and CRAs were the most efficacious in decontamination of C. difficile vegetative cells and spores, the efficacy of the CRAs were concentration dependent irrespective of PCR-ribotype. However, there were differences observed in the susceptibility of the PCR-ribotypes, independent of the concentrations tested for Virkon®, Newgenn®, Proceine 40® and Hibiscrub®. Whereas, for Steri7® and Biocleanse® the difference observed between the disinfectants were dependent on both PCR-ribotype and concentration. The oxidizing agent Perasafe® was consistently efficacious across all three PCR ribotypes at varying concentrations; with a consistent five Log10 reduction in spore titre. The PCR-ribotype and concentration dependent differences in the efficacy of the disinfectants in this study indicate that disinfectant choice is a factor for llimiting the survival and transmission of C. difficile spores in healthcare settings

Quantum Bisimilarity via Barbs and Contexts: Curbing the Power of Non-deterministic Observers

Past years have seen the development of a few proposals for quantum extensions of process calculi. The rationale is clear: with the development of quantum communication protocols, there is a need to abstract and focus on the basic features of quantum concurrent systems, like CCS and CSP have done for their classical counterparts. So far, though, no accepted standard has emerged, neither for the syntax nor for the behavioural semantics. Indeed, the various proposals do not agree on what should be the observational properties of quantum values, and as a matter of fact, the soundness of such properties has never been validated against the prescriptions of quantum theory. To this aim, we introduce a new calculus, Linear Quantum CCS (lqCCS), and investigate the features of behavioural equivalences based on barbs and contexts. Our calculus can be thought of as an asynchronous, linear version of qCCS, which is in turn based on value-passing CCS. The combination of linearity and asynchronous communication fits well with the properties of quantum systems (e.g. the no-cloning theorem), since it ensures that each qubit is sent exactly once, precisely specifying which qubits of a process interact with the context. We exploit contexts to examine how bisimilarities relate to quantum theory. We show that the observational power of general contexts is incompatible with quantum theory: roughly, they can perform non-deterministic moves depending on quantum values without measuring (hence perturbing) them. Therefore, we refine the operational semantics in order to prevent contexts from performing unfeasible non-deterministic choices. This induces a coarser bisimilarity that better fits the quantum setting: (i) it lifts the indistinguishability of quantum states to the distributions of processes and, despite the additional constraints, (ii) it preserves the expressiveness of non-deterministic choices based on classical information. To the best of our knowledge, our semantics is the first one that satisfies the two properties above