A perspective on SIDS pathogenesis. The hypotheses: plausibility and evidence

Several theories of the underlying mechanisms of Sudden Infant Death Syndrome (SIDS) have been proposed. These theories have born relatively narrow beach-head research programs attracting generous research funding sustained for many years at expense to the public purse. This perspective endeavors to critically examine the evidence and bases of these theories and determine their plausibility; and questions whether or not a safe and reasoned hypothesis lies at their foundation. The Opinion sets specific criteria by asking the following questions: 1. Does the hypothesis take into account the key pathological findings in SIDS? 2. Is the hypothesis congruent with the key epidemiological risk factors? 3. Does it link 1 and 2? Falling short of any one of these answers, by inference, would imply insufficient grounds for a sustainable hypothesis. Some of the hypotheses overlap, for instance, notional respiratory failure may encompass apnea, prone sleep position, and asphyxia which may be seen to be linked to co-sleeping. For the purposes of this paper, each element will be assessed on the above criteria

Children Base Their Investment on Calculated Pay-Off

To investigate the rise of economic abilities during development we studied children aged between 3 and 10 in an exchange situation requiring them to calculate their investment based on different offers. One experimenter gave back a reward twice the amount given by the children, and a second always gave back the same quantity regardless of the amount received. To maximize pay-offs children had to invest a maximal amount with the first, and a minimal amount with the second. About one third of the 5-year-olds and most 7- and 10-year-olds were able to adjust their investment according to the partner, while all 3-year-olds failed. Such performances should be related to the rise of cognitive and social skills after 4 years

Semi-Parametric Graphical Estimation Techniques for Long-Memory Data

This paper reviews several periodogram-based methods for estimating the long-memory parameter H in time series and suggests a way to robustify them. The high frequencies tend to bias the estimates. Using only low frequencies eliminates the bias but increases the variance. We hence suggest plotting the estimates of H as a function of a parameter which balances bias versus variance and, if the plot flattens in a central region, to use the flat part for estimating H. We apply this technique to the periodogram regression method, the Whittle approximation to maximum likelihood and to the local Whittle method. We investigate its effectiveness on several simulated fractional ARIMA series and also apply it to estimate the long-memory parameter H in computer network traffic. 1 Introduction Time series with long memory have been considered in many fields including hydrology, biology and computer networks. Unfortunately, estimating the long memory (long-range dependence) parameter H in a given d..