3,350 research outputs found
Big Data Techniques and Talent Management: Recommendations for Organizations and a Research Agenda for I-O Psychologists
Big data and its applicability to talent management (TM) as defined by Rotolo et al. (2018) has already been recognized by many outside the field of I-O psychology. The market is beginning to include offerings from vendors for products that use some combination of big data techniques to process vast amounts of data or previously unanalyzable data, which they claim will improve components of TM for organizations. Unfortunately, as noted in the focal article, this “frontier” issue makes it difficult for organizations to separate the wheat from the chaff. Further, with few exceptions, I-O psychology is just beginning to inform organizations about whether and how big data can be used for the purposes of TM
The PASTEL catalogue of stellar parameters
The PASTEL catalogue is an update of the [Fe/H] catalogue, published in 1997
and 2001. It is a bibliographical compilation of stellar atmospheric parameters
providing (Teff,logg,[Fe/H]) determinations obtained from the analysis of high
resolution, high signal-to-noise spectra, carried out with model atmospheres.
PASTEL also provides determinations of the one parameter Teff based on various
methods. It is aimed in the future to provide also homogenized atmospheric
parameters and elemental abundances, radial and rotational velocities. A web
interface has been created to query the catalogue on elaborated criteria.
PASTEL is also distributed through the CDS database and VizieR. To make it as
complete as possible, the main journals have been surveyed, as well as the CDS
database, to find relevant publications. The catalogue is regularly updated
with new determinations found in the literature. As of Febuary 2010, PASTEL
includes 30151 determinations of either Teff or (Teff,logg,[Fe/H]) for 16649
different stars corresponding to 865 bibliographical references. Nearly 6000
stars have a determination of the three parameters (Teff,logg,[Fe/H]) with a
high quality spectroscopic metallicity.Comment: 5 pages, accepted for publication in A&A. The PASTEL catalogue can be
queried at http://pastel.obs.u-bordeaux1.fr/ or
http://vizier.u-strasbg.fr/viz-bin/VizieR?-source=B/paste
Spin gating electrical current
We use an aluminium single electron transistor with a magnetic gate to
directly quantify the chemical potential anisotropy of GaMnAs materials.
Uniaxial and cubic contributions to the chemical potential anisotropy are
determined from field rotation experiments. In performing magnetic field sweeps
we observe additional isotropic magnetic field dependence of the chemical
potential which shows a non-monotonic behavior. The observed effects are
explained by calculations based on the kinetic
exchange model of ferromagnetism in GaMnAs. Our device inverts the conventional
approach for constructing spin transistors: instead of spin-transport
controlled by ordinary gates we spin-gate ordinary charge transport.Comment: 5 pages, 4 figure
Antitumour responses induced by a cell-based Reovirus vaccine in murine lung and melanoma models
Background: The ever increasing knowledge in the areas of cell biology, the immune system and the mechanisms of cancer are allowing a new phase of immunotherapy to develop. The aim of cancer vaccination is to activate the host immune system and some success has been observed particularly in the use of the BCG vaccine for bladder cancer as an immunostimulant. Reovirus, an orphan virus, has proven itself as an oncolytic virus in vitro and in vivo. Over 80 % of tumour cell lines have been found to be susceptible to Reovirus infection and it is currently in phase III clinical trials. It has been shown to induce immune responses to tumours with very low toxicities. Methods: In this study, Reovirus was examined in two main approaches in vivo, in mice, using the melanoma B16F10 and Lewis Lung Carcinoma (LLC) models. Initially, mice were treated intratumourally (IT) with Reovirus and the immune responses determined by cytokine analysis. Mice were also vaccinated using a cell-based Reovirus vaccine and subsequently exposed to a tumourigenic dose of cells (B16F10 or LLC). Using the same cell-based Reovirus vaccine, established tumours were treated and subsequent immune responses and virus retrieval investigated. Results: Upregulation of several cytokines was observed following treatment and replication-competent virus was also retrieved from treated tumours. Varying levels of cytokine upregulation were observed and no replication-competent virus was retrieved in vaccine-treated mice. Prolongation of survival and delayed tumour growth were observed in all models and an immune response to Reovirus, either using Reovirus alone or a cell-based vaccine was also observed in all mice. Conclusion: This study provides evidence of immune response to tumours using a cell-based Reovirus vaccine in both tumour models investigated, B16F10 and LLC, cytokine induction was observed with prolongation of survival in almost all cases which may suggest a new method for using Reovirus in the clinic
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