38 research outputs found
Avaliação de cultivares de soja sobre braquiária no sistema plantio direto, safra 1998/99, em Piacatu, SP.
bitstream/item/39753/1/COT-11-1999.pd
Época de semeadura: um importante fator que afeta a produtividade da cultura da soja.
Temperatura do ar; Umidade do solo; FotoperĂodo.bitstream/item/65720/1/DOC34.pd
Resilience skills used by front-line workers to assemble precast concrete structures: an exploratory study
He votes or she votes? Female and male discursive strategies in Twitter political hashtags
In this paper, we conduct a study about differences between female and
male discursive strategies when posting in the microblogging service
Twitter, with a particular focus on the hashtag designation process
during political debate. The fact that men and women use language in
distinct ways, reverberating practices linked to their expected roles in
the social groups, is a linguistic phenomenon known to happen in
several cultures and that can now be studied on the Web and on online
social networks in a large scale enabled by computing power. Here, for
instance, after analyzing tweets with political content posted during
Brazilian presidential campaign, we found out that male Twitter users,
when expressing their attitude toward a given candidate, are more prone
to use imperative verbal forms in hashtags, while female users tend to
employ declarative forms. This difference can be interpreted as a sign
of distinct approaches in relation to other network members: for
example, if political hashtags are seen as strategies of persuasion in
Twitter, imperative tags could be understood as more overt ways of
persuading and declarative tags as more indirect ones. Our findings help
to understand human gendered behavior in social networks and contribute
to research on the new fields of computer-enabled Internet linguistics
and social computing, besides being useful for several computational
tasks such as developing tag recommendation systems based on users'
collective preferences and tailoring targeted advertising strategies,
among others.FGW – Publications without University Leiden contrac
Induction of CD4+CD25+FOXP3+ Regulatory T Cells during Human Hookworm Infection Modulates Antigen-Mediated Lymphocyte Proliferation
Hookworm infection is considered one of the most important poverty-promoting neglected tropical diseases, infecting 576 to 740 million people worldwide, especially in the tropics and subtropics. These blood-feeding nematodes have a remarkable ability to downmodulate the host immune response, protecting themselves from elimination and minimizing severe host pathology. While several mechanisms may be involved in the immunomodulation by parasitic infection, experimental evidences have pointed toward the possible involvement of regulatory T cells (Tregs) in downregulating effector T-cell responses upon chronic infection. However, the role of Tregs cells in human hookworm infection is still poorly understood and has not been addressed yet. In the current study we observed an augmentation of circulating CD4+CD25+FOXP3+ regulatory T cells in hookworm-infected individuals compared with healthy non-infected donors. We have also demonstrated that infected individuals present higher levels of circulating Treg cells expressing CTLA-4, GITR, IL-10, TGF-β and IL-17. Moreover, we showed that hookworm crude antigen stimulation reduces the number of CD4+CD25+FOXP3+ T regulatory cells co-expressing IL-17 in infected individuals. Finally, PBMCs from infected individuals pulsed with excreted/secreted products or hookworm crude antigens presented an impaired cellular proliferation, which was partially augmented by the depletion of Treg cells. Our results suggest that Treg cells may play an important role in hookworm-induced immunosuppression, contributing to the longevity of hookworm survival in infected people