Reflexiones económico-políticas

Sign.: a-b8, A-Q

Real Cedula de S. M. a consulta del consejo-pleno en que se encarga a los ordinarios eclesiasticos de estos Reynos contribuyan por su parte à que tenga efecto lo dispuesto en la Pragmatica-Sancion, expedida con la misma fecha, acerca del consentimiento paterno y demas que están en lugar de padres, antes de celebrar sus esponsales los hijos de familias, con lo demás que expresa, en conformidad de las leyes del Reyno y disposiciones canónicas

Texto certificado por Antonio Martinez SalazarTexto fechado en El Pardo a 23 de marzo de 1776Última h. en bl.Esc. real xil. en port

Real Cédula, 1773-09-16

Texto fechado en San Ildefonso a 16 de septiembre de 1773Copia certificada por Antonio Martinez SalazarPort. con esc. xil. rea

Real Cédula, 1782-06-02

Copia firmada por Antonio Martínez SalazarSign.: [ ]1, A17Port. con esc. real xil

Provisión, 1786-02-21

Al final de texto: Provision inserta la Real Resolucion, que comprende para la execucion de las penas, y demas a que es referente, comprensibas à fraudes de la renta del tabaco de este Reyno de NavarraTexto firmado por Manuel Fermín Miura por mandado de Ramón Iñiguez de BeorteguiTexto fechado en Pamplona: 21 febrero 1786Sign.: [ ]8Port. con esc. xil. rea

Alcohol affects neuronal substrates of response inhibition but not of perceptual processing of stimuli signalling a stop response

Alcohol impairs inhibitory control, including the ability to terminate an initiated action. While there is increasing knowledge about neural mechanisms involved in response inhibition, the level at which alcohol impairs such mechanisms remains poorly understood. Thirty-nine healthy social drinkers received either 0.4g/kg or 0.8g/kg of alcohol, or placebo, and performed two variants of a Visual Stop-signal task during acquisition of functional magnetic resonance imaging (fMRI) data. The two task variants differed only in their instructions: in the classic variant (VSST), participants inhibited their response to a “Go-stimulus” when it was followed by a “Stop-stimulus”. In the control variant (VSST_C), participants responded to the “Go-stimulus” even if it was followed by a “Stop-stimulus”. Comparison of successful Stop-trials (Sstop)>Go, and unsuccessful Stop-trials (Ustop)>Sstop between the three beverage groups enabled the identification of alcohol effects on functional neural circuits supporting inhibitory behaviour and error processing. Alcohol impaired inhibitory control as measured by the Stop-signal reaction time, but did not affect other aspects of VSST performance, nor performance on the VSST_C. The low alcohol dose evoked changes in neural activity within prefrontal, temporal, occipital and motor cortices. The high alcohol dose evoked changes in activity in areas affected by the low dose but importantly induced changes in activity within subcortical centres including the globus pallidus and thalamus. Alcohol did not affect neural correlates of perceptual processing of infrequent cues, as revealed by conjunction analyses of VSST and VSST_C tasks. Alcohol ingestion compromises the inhibitory control of action by modulating cortical regions supporting attentional, sensorimotor and action-planning processes. At higher doses the impact of alcohol also extends to affect subcortical nodes of fronto-basal ganglia- thalamo-cortical motor circuits. In contrast, alcohol appears to have little impact on the early visual processing of infrequent perceptual cues. These observations clarify clinically-important effects of alcohol on behaviour

High-sensitivity diamond magnetometer with nanoscale resolution

We present a novel approach to the detection of weak magnetic fields that takes advantage of recently developed techniques for the coherent control of solid-state electron spin quantum bits. Specifically, we investigate a magnetic sensor based on Nitrogen-Vacancy centers in room-temperature diamond. We discuss two important applications of this technique: a nanoscale magnetometer that could potentially detect precession of single nuclear spins and an optical magnetic field imager combining spatial resolution ranging from micrometers to millimeters with a sensitivity approaching few femtotesla/Hz$^{1/2}$.Comment: 29 pages, 4 figure

Real Cédula, 1771-08-18

Copia certificada por Antonio Martínez SalazarSign.: A4Port. esc. real xil

Geometry of open strings ending on backreacting D3-branes

We investigate open string theory on backreacting D3-branes using a spacetime approach. We study in detail the half-BPS supergravity solutions describing open strings ending on D3-branes, in the near horizon of the D3-branes. We recover quantitatively several non-trivial features of open string physics including the appearance of D3-brane spikes, the polarization of fundamental strings into D5-branes, and the Hanany-Witten effect. Finally we detail the computation of the gravitational potential between two open strings, and contrast it with the holographic computation of Wilson lines. We argue that the D-brane backreaction has a large influence on the low-energy gravity, which may lead to experimental tests for string theory brane-world scenarios.Comment: 64 pages, 20 figure