60 research outputs found

    Statistical strategies for avoiding false discoveries in metabolomics and related experiments

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    The Means of Management Control

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    In the understanding of managerial control over work, the labour process literature has been very influential. Recent critical contributions from the sociological tradition have, however, served to so fragment the underlying perspective that its coherence is now threatened. This paper seeks to demonstrate how a dialectical analysis can lay the basis for a viable amended approach. The need for a dialectical framework has often been urged - illustrations of such a perspective in operation, however, are rare. Using a series of examples, this paper argues that the dialectic of work control can be revealed by focussing on two phenomena: the 'levels' and 'circuits' of control

    Composition and synthesis of raphide crystals and druse crystals in berries of Vitis vinifera L. cv. Cabernet Sauvignon: Ascorbic acid as precursor for both oxalic and tartaric acids as revealed by radiolabelling studies

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    Copyright © 2008 Australian Society of Viticulture and Oenology Inc.Biomineralisation in the fleshy pericarp of berries of Vitis vinifera L. gives rise to crystals of two distinct forms, viz. raphides and druses, which are found in exocarp and endocarp cells respectively. Druses have generally been considered as crystalline aggregates of calcium oxalate. However, the organic moiety of raphide crystals has been commonly accepted as tartrate, although we have found no analytical data to support that assumption. We now present TEM and X-ray powder diffraction analysis data showing that raphide crystals of V. vinifera berries are composed of calcium oxalate monohydrate. This work also established ascorbic acid as the biosynthetic precursor of both oxalic and tartaric acids. When ascorbic acid labelled with ¹⁴C at position 1 was introduced into berries via the rachis, 21% and 52% of the added radiolabel was recovered as oxalic and tartaric acids respectively. Purified crystals from the radiolabelled grape berries contained approximately 20% of the original radioactivity, further confirming the role of ascorbic acid in oxalic acid biosynthesis. To our knowledge, this is the first evidence to be published on the formation of oxalic and tartaric acids from ascorbic acid via two distinct pathways operating within the same physiological entity (organ).Seth Debolt, Jim Hardie, Steve Tyerman and Christopher M. For
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