56 research outputs found
Detection of developmentally controlled plasma membrane antigens of dictyostelium discoideum cells in SDS-polyacrylamide gels
SPECIFIC INHIBITION OF LYMPHOID COMPLEMENT RECEPTORS BY ANTI-H-2 SERA: EVIDENCE FOR A NEW H-2 LINKED POLYMORPHISM
Certain anti-H-2 sera contain an antibody-like activity which specifically inhibits EAC rosette formation by lymphoid (and not myeloid) cells of certain mouse strains. Studies in congenic recombinant mouse strains strongly indicate that at least part of the control of susceptibility to inhibition by these antisera is mediated by H-2 linked genes, mapping in the I-C subregion or the S region. The strain distribution of the trait CRIS indicates that certain H-2 identical mice behave differently from one another, pointing toward a component of non-H-2 modulation of the H-2 linked gene (or to a previously unsuspected H-2 difference). Positive sera were usually raised across differences in the D end of the H-2 complex. The complex implications of this system must be considered in the light of known S region involvement in complement metabolism.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73055/1/j.1744-313X.1975.tb00549.x.pd
Application of drug discovery software to the identification of heparin-binding sites on protein surfaces: a computational survey of the 4-helix cytokines
Up-Regulation of Heparanase in the Ethmoid Sinus Mucosa of Patients with Chronic Sinusitis
The Use of CFSE-like Dyes for Measuring Lymphocyte Proliferation : Experimental Considerations and Biological Variables
The measurement of CFSE dilution by flow cytometry is a powerful experimental tool to
measure lymphocyte proliferation. CFSE fluorescence precisely halves after each cell
division in a highly predictable manner and is thus highly amenable to mathematical
modelling. However, there are several biological and experimental conditions that can
affect the quality of the proliferation data generated, which may be important to consider
when modelling dye dilution data sets. Here we overview several of these variables
including the type of fluorescent dye used to monitor cell division, dye labelling
methodology, lymphocyte subset differences, in vitro versus in vivo experimental assays,
cell autofluorescence, and dye transfer between cells
Inhibitory Effects of Polycations on the Replication of Enveloped Viruses (HIV, HSV, CMV, RSV, Influenza A Virus and Togaviruses) in vitro
Utilisation of Gas-Phase Ion—Molecule Reactions for Differentiation between Phospho- and Sulfocarbohydrates
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