Overview. Standing on the Threshold: Food Justice in India

This piece provides a summary of the articles detailing the recent fight for food justice in India. It begins by providing an overview of the state of food and nutrition in India and reflects on the experience to date of the role of the courts in promoting food justice. It goes on to describe some of the ongoing struggles to claim rights and justice, highlighting implementation, capacity, incentive and cultural barriers to realisation. Finally, this article focuses on the enduring and new challenges to attaining food security in India, strong food justice system or not

The Giant Inflaton

We investigate a new mechanism for realizing slow roll inflation in string theory, based on the dynamics of p anti-D3 branes in a class of mildly warped flux compactifications. Attracted to the bottom of a warped conifold throat, the anti-branes then cluster due to a novel mechanism wherein the background flux polarizes in an attempt to screen them. Once they are sufficiently close, the M units of flux cause the anti-branes to expand into a fuzzy NS5-brane, which for rather generic choices of p/M will unwrap around the geometry, decaying into D3-branes via a classical process. We find that the effective potential governing this evolution possesses several epochs that can potentially support slow-roll inflation, provided the process can be arranged to take place at a high enough energy scale, of about one or two orders of magnitude below the Planck energy; this scale, however, lies just outside the bounds of our approximations.Comment: 31 pages, 4 figures, LaTeX. v2: references added, typos fixe

Null Brane Intersections

We study pairs of planar D-branes intersecting on null hypersurfaces, and other related configurations. These are supersymmetric and have finite energy density. They provide open-string analogues of the parabolic orbifold and null-fluxbrane backgrounds for closed superstrings. We derive the spectrum of open strings, showing in particular that if the D-branes are shifted in a spectator dimension so that they do not intersect, the open strings joining them have no asymptotic states. As a result, a single non-BPS excitation can in this case catalyze a condensation of massless modes, changing significantly the underlying supersymmetric vacuum state. We argue that a similar phenomenon can modify the null cosmological singularity of the time-dependent orbifolds. This is a stringy mechanism, distinct from black-hole formation and other strong gravitational instabilities, and one that should dominate at weak string coupling. A by-product of our analysis is a new understanding of the appearance of 1/4 BPS threshold bound states, at special points in the moduli space of toroidally-compactified type-II string theory.Comment: Tex file, uses harvmac, 24 pages with 5 figures. Corrected typos and added references. Final version to appear in JHE

D-terms and D-strings in open string models

We study the Fayet-Iliopoulos (FI) D-terms on D-branes in type II Calabi-Yau backgrounds. We provide a simple worldsheet proof of the fact that, at tree level, these terms only couple to scalars in closed string hypermultiplets. At the one-loop level, the D-terms get corrections only if the gauge group has an anomalous spectrum, with the anomaly cancelled by a Green-Schwarz mechanism. We study the local type IIA model of D6-branes at SU(3) angles and show that, as in field theory, the one-loop correction suffers from a quadratic divergence in the open string channel. By studying the closed string channel, we show that this divergence is related to a closed string tadpole, and is cancelled when the tadpole is cancelled. Next, we study the cosmic strings that arise in the supersymmetric phases of these systems in light of recent work of Dvali et. al. In the type IIA intersecting D6-brane examples, we identify the D-term strings as D4-branes ending on the D6-branes. Finally, we use N=1 dualities to relate these results to previous work on the FI D-term of heterotic strings.Comment: 29 pages, 5 figures; v2: improved referencin

Dibaryon Spectroscopy

The AdS/CFT correspondence relates dibaryons in superconformal gauge theories to holomorphic curves in Kaehler-Einstein surfaces. The degree of the holomorphic curves is proportional to the gauge theory conformal dimension of the dibaryons. Moreover, the number of holomorphic curves should match, in an appropriately defined sense, the number of dibaryons. Using AdS/CFT backgrounds built from the generalized conifolds of Gubser, Shatashvili, and Nekrasov (1999), we show that the gauge theory prediction for the dimension of dibaryonic operators does indeed match the degree of the corresponding holomorphic curves. For AdS/CFT backgrounds built from cones over del Pezzo surfaces, we are able to match the degree of the curves to the conformal dimension of dibaryons for the n'th del Pezzo surface, n=1,2,...,6. Also, for the del Pezzos and the A_k type generalized conifolds, for the dibaryons of smallest conformal dimension, we are able to match the number of holomorphic curves with the number of possible dibaryon operators from gauge theory.Comment: 30 pages, 6 figures, corrected refs; v3 typos correcte

Axions In String Theory

In the context of string theory, axions appear to provide the most plausible solution of the strong CP problem. However, as has been known for a long time, in many string-based models, the axion coupling parameter F_a is several orders of magnitude higher than the standard cosmological bounds. We re-examine this problem in a variety of models, showing that F_a is close to the GUT scale or above in many models that have GUT-like phenomenology, as well as some that do not. On the other hand, in some models with Standard Model gauge fields supported on vanishing cycles, it is possible for F_a to be well below the GUT scale.Comment: 62 pages, v2; references, acknowledgements and minor corrections adde

Real-time gauge/gravity duality: Prescription, Renormalization and Examples

We present a comprehensive analysis of the prescription we recently put forward for the computation of real-time correlation functions using gauge/gravity duality. The prescription is valid for any holographic supergravity background and it naturally maps initial and final data in the bulk to initial and final states or density matrices in the field theory. We show in detail how the technique of holographic renormalization can be applied in this setting and we provide numerous illustrative examples, including the computation of time-ordered, Wightman and retarded 2-point functions in Poincare and global coordinates, thermal correlators and higher-point functions.Comment: 85 pages, 13 figures; v2: added comments and reference

Antimetastatic Potential of PAI-1 Specific RNA Aptamers

The serine protease inhibitor plasminogen activator inhibitor-1 (PAI-1) is increased in several cancers, including breast, where it is associated with a poor outcome. Metastatic breast cancer has a dismal prognosis, as evidenced by treatment goals that are no longer curative but are largely palliative in nature. PAI-1 competes with integrins and the urokinase plasminogen activator receptor on the surface of breast cancer cells for binding to vitronectin. This results in the detachment of tumor cells from the extracellular matrix, which is critical to the metastatic process. For this reason, we sought to isolate RNA aptamers that disrupt the interaction between PAI-1 and vitronectin. Through utilization of combinatorial chemistry techniques, aptamers have been selected that bind to PAI-1 with high affinity and specificity. We identified two aptamers, WT-15 and SM-20, that disrupt the interactions between PAI-1 and heparin, as well as PAI-1 and vitronectin, without affecting the antiprotease activity of PAI-1. Furthermore, SM-20 prevented the detachment of breast cancer cells (MDA-MB-231) from vitronectin in the presence of PAI-1, resulting in an increase in cellular adhesion. Therefore, the PAI-1 aptamer SM-20 demonstrates therapeutic potential as an antimetastatic agent and could possibly be used as an adjuvant to traditional chemotherapy for breast cancer.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/78126/1/oli.2008.0177.pd

ASTRO-F - The next generation of mid-infrared surveys

We present basic observational strategies for ASTRO-F (also known as the Imaging Infra Red Surveyor (IRIS)) to be launched in 2004 by the Japanese Institute of Space and Astronautical Science (ISAS). We examine 2 survey scenarios, a deep ~1sq.deg. survey reaching sensitivities an order of magnitude below than the deepest surveys performed by ISO in the mid-IR, and a shallow \~18sq.deg mid-infrared (7-25um in 6 bands) covering an area greater than the entire area covered by all ISO mid-IR surveys. Using 2 cosmological models the number of galaxies predicted for each survey is calculated. The first model uses an enhancement of the pure luminosity evolution model of Pearson & Rowan-Robinson while the new models incorporate a strongly evolving ULIG component. For the deep survey, between 20,000-30,000 galaxies should be detected in the shortest wavebands and ~5000 in the longest (25um) band. The shallow survey would be expected to detect of the order of 100,000 - 150,000 sources.Comment: 17 pages, 13 figures, accepted by MNRA

Toroidal Orientifolds in IIA with General NS-NS Fluxes

Type IIA toroidal orientifolds offer a promising toolkit for model builders, especially when one includes not only the usual fluxes from NS-NS and R-R field strengths, but also fluxes that are T-dual to the NS-NS three-form flux. These new ingredients are known as metric fluxes and non-geometric fluxes, and can help stabilize moduli or can lead to other new features. In this paper we study two approaches to these constructions, by effective field theory or by toroidal fibers twisted over a toroidal base. Each approach leads us to important observations, in particular the presence of D-terms in the four-dimensional effective potential in some cases, and a more subtle treatment of the quantization of the general NS-NS fluxes. Though our methods are general, we illustrate each approach on the example of an orientifold of T^6/Z_4.Comment: 59 pages, references adde