Psychophysiological measures of driver distraction and workload while intoxicated

The crash risk associated with cell phone use while driving is a contentious issue. Many states are introducing Advanced Traveler Information Systems (ATIS) that may be accessed with cell phones while driving (e.g., 511 Traveler Information Services). In these contexts, there is a need for relevant research to determine the risk of cell phone use. This study compared driver performance while conversing on a hands-free cell phone to conditions of operating common in-vehicle controls (e.g., radio, fan, air conditioning) and alcohol intoxication (BAC 0.08). In addition, the study examined the combined effects of being distracted and being intoxicated given that there may be a higher risk of a crash if the driver engages in a combination of risk factors. During simulated traffic scenarios, resource allocation was assessed through an eventrelated potential (ERP) novelty oddball paradigm. Intoxicated drivers were less attentive to all stimuli and drivers engaged in secondary tasks had weaker responses to unexpected novel sounds in brain regions associated with evaluative processing. Drivers conversing on the cell phone and in-vehicle tasks while sober had lower accuracy during the target tone task than intoxicated drivers not completing any secondary task

Frequency down conversion through Bose condensation of light

We propose an experimental set up allowing to convert an input light of wavelengths about $1-2 \mu m$ into an output light of a lower frequency. The basic principle of operating relies on the nonlinear optical properties exhibited by a microcavity filled with glass. The light inside this material behaves like a 2D interacting Bose gas susceptible to thermalise and create a quasi-condensate. Extension of this setup to a photonic bandgap material (fiber grating) allows the light to behave like a 3D Bose gas leading, after thermalisation, to the formation of a Bose condensate. Theoretical estimations show that a conversion of $1 \mu m$ into $1.5 \mu m$ is achieved with an input pulse of about $1 ns$ with a peak power of $10^3 W$, using a fiber grating containing an integrated cavity of size about $500 \mu m \times 100 \mu m^2$.Comment: 4 pages, 1 figure

Intra-arterial ultrasonic imaging for recanalization by spark erosion

Presently several new methods are being developed to recanalize obstructed arteries during catheterization. Intra-arterial high frequency ultrasonic imaging may be used as a guidance for these new techniques. Spark erosion is a new obstruction removal technology. Experiments have shown that this method can be applied in a selective way. An ultrasonic intra-arterial imaging system allows for the proper indication of the spark erosion catheter relative to the obstruction. The first in vitro results of this study illustrate that integration of catheter tip imaging and spark erosion is possible

Appeasing pheromones for the management of stress and aggression during conservation of wild canids: could the solution be right under our nose?

Thirty-six species of canid exist globally, two are classified as critically endangered, three as endangered, and five as near threatened. Human expansion and the coinciding habitat fragmentation necessitate conservation interventions to mitigate concurrent population deterioration. The current conservation management of wild canids includes animal translocation and artificial pack formation. These actions often cause chronic stress, leading to increased aggression and the suppression of the immune and reproductive systems. Castration and pharmaceutical treatments are currently used to reduce stress and aggression in domestic and captive canids. The undesirable side effects make such treatments inadvisable during conservation management of wild canids. Pheromones are naturally occurring chemical messages that modulate behaviour between conspecifics; as such, they offer a natural alternative for behaviour modification. Animals are able to distinguish between pheromones of closely related species through small compositional differences but are more likely to have greater responses to pheromones from individuals of the same species. Appeasing pheromones have been found to reduce stress- and aggression-related behaviours in domestic species, including dogs. Preliminary evidence suggests that dog appeasing pheromones (DAP) may be effective in wild canids. However, the identification and testing of species-specific derivatives could produce more pronounced and beneficial behavioural and physiological changes in target species. In turn, this could provide a valuable tool to improve the conservation management of many endangered wild canids

Multi-band material loaded Low-SAR antenna for mobile handsets

Previous studies have shown that monopoles loaded with material of equal permittivity and permeability values give increased bandwidth and radiation efficiency for a given size reduction. Positioning the monopole orthogonally to the head directs pattern nulls towards the head, which leads to low Specific Absorption Rates (SAR). Simulated results of the material loaded monopole showed dual-mode behaviour. In this paper, the simple monopole is translated into a compact antenna design suitable for mobile handsets. Metallic strips are printed on the material block to increase the number of modes and realise a small, quad-band, low-SAR handset antenna

Volumetric intracoronary ultrasound: a new maximum confidence approach for the quantitative assessment of progression-regression of atherosclerosis?

Quantitative assessment of atherosclerosis during its natural history and following therapeutic interventions is important, as cardiovascular disease remains the most significant cause of morbidity and mortality in industrial societies. While coronary angiography delineates the vessel lumen, permitting only the indirect determination of atherosclerotic wall changes encroaching upon the lumen, intracoronary ultrasound permits direct plaque assessment and quantification. The angiographic percent diameter stenosis, previously suggested as measure of a maximum confidence approach, is still commonly used to quantify stenosis severity, but the reference segments which are required for angiographic interpolation of the normal vessel dimensions are frequently involved in the general process of atherosclerosis, including progression or regression. Considering also the variability of vascular remodeling during the evolution of atherosclerosis, including compensatory enlargement and paradoxical arterial shrinkage, intracoronary ultrasound appears currently to be the only reliable technique to measure plaque burden and progression or regression of atherosclerosis. However, correct matching of the site of measurement at follow-up with the site of the initial ultrasound study is often difficult to achieve, but is significantly facilitated by the use of volumetric intracoronary ultrasound. This approach permits not only area measurement, but also measurement of plaque volume, which appears to be the ideal measure for quantifying the atherosclerotic plaque, as it is highly reproducible and directly reflects the changes of an entire arterial segment

Variance based weighting of multisensory head rotation signals for verticality perception

We tested the hypothesis that the brain uses a variance-based weighting of multisensory cues to estimate head rotation to perceive which way is up. The hypothesis predicts that the known bias in perceived vertical, which occurs when the visual environment is rotated in a vertical-plane, will be reduced by the addition of visual noise. Ten healthy participants sat head-fixed in front of a vertical screen presenting an annulus filled with coloured dots, which could rotate clockwise or counter-clockwise at six angular velocities (1, 2, 4, 6, 8, 16°/s) and with six levels of noise (0, 25, 50, 60, 75, 80%). Participants were required to keep a central bar vertical by rotating a hand-held dial. Continuous adjustments of the bar were required to counteract low-amplitude low-frequency noise that was added to the bar's angular position. During visual rotation, the bias in verticality perception increased over time to reach an asymptotic value. Increases in visual rotation velocity significantly increased this bias, while the addition of visual noise significantly reduced it, but did not affect perception of visual rotation velocity. The biasing phenomena were reproduced by a model that uses a multisensory variance-weighted estimate of head rotation velocity combined with a gravito-inertial acceleration signal (GIA) from the vestibular otoliths. The time-dependent asymptotic behaviour depends on internal feedback loops that act to pull the brain's estimate of gravity direction towards the GIA signal. The model's prediction of our experimental data furthers our understanding of the neural processes underlying human verticality perception

Cyclic changes of blood echogenicity in high-frequency ultrasound

Ultrasound images from human arteries obtained in vivo with an intravascular 30 MHz ultrasound imaging device show that blood echogenicity changes during the cardiac cycle. Quantitative measurements of blood echogenicity during the cardiac cycle suggest that these variations may be related to changes in the state of erythrocyte aggregation, which are induced by varying shear rate