373 research outputs found
Lifetime Maximization for Amplify-and-Forward Cooperative Networks
[[abstract]]Power allocation strategies are devised to maximize the network lifetime of amplify-and-forward (AF) cooperative networks. We consider the scenario where one source and multiple partners cooperate to transmit messages to the destination. The powers emitted by the users are subject to the SNR requirement at the destination. First, the power allocation strategy that demands the minimum instantaneous aggregate transmit power of all cooperating partners is described and analyzed. The optimal solution results in a form of selective relaying; namely, the user with the best channel condition is selected to help in relaying the message. However, this instantaneous power minimization strategy does not necessarily maximize the lifetime of battery-limited systems. Then, we propose three AF cooperative schemes to exploit the channel state information (CSI), the residual battery energy and the QoS requirement. It is shown that the network lifetime can be extended considerably by taking all these three factors into account.[[fileno]]2030137030021[[department]]電機工程學
Gravitons and Lightcone Fluctuations
Gravitons in a squeezed vacuum state, the natural result of quantum creation
in the early universe or by black holes, will introduce metric fluctuations.
These metric fluctuations will introduce fluctuations of the lightcone. It is
shown that when the various two-point functions of a quantized field are
averaged over the metric fluctuations, the lightcone singularity disappears for
distinct points. The metric averaged functions remain singular in the limit of
coincident points. The metric averaged retarded Green's function for a massless
field becomes a Gaussian which is nonzero both inside and outside of the
classical lightcone. This implies some photons propagate faster than the
classical light speed, whereas others propagate slower. The possible effects of
metric fluctuations upon one-loop quantum processes are discussed and
illustrated by the calculation of the one-loop electron self-energy.Comment: 18pp, LATEX, TUTP-94-1
Relativistic Ring-Diagram Nuclear Matter Calculations
A relativistic extension of the particle-particle hole-hole ring-diagram
many-body formalism is developed by using the Dirac equation for
single-particle motion in the medium. Applying this new formalism, calculations
are performed for nuclear matter. The results show that the saturation density
is improved and the equation of state becomes softer as compared to
corresponding Dirac-Brueckner-Hartree-Fock calculations. Using the Bonn A
potential, nuclear matter is predicted to saturate at an energy per nucleon of
--15.30 MeV and a density equivalent to a Fermi momentum of 1.38 fm, in
excellent agreement with empirical information. The compression modulus is 152
MeV at the saturation point.Comment: 23 pages text (LaTex) and 2 figures (paper, will be faxed upon
request), UI-NTH-92-0
Improved Lattice Gauge Field Hamiltonian
Lepage's improvement scheme is a recent major progress in lattice ,
allowing to obtain continuum physics on very coarse lattices. Here we discuss
improvement in the Hamiltonian formulation, and we derive an improved
Hamiltonian from a lattice Lagrangian free of errors. We do this by
the transfer matrix method, but we also show that the alternative via Legendre
transformation gives identical results. We consider classical improvement,
tadpole improvement and also the structure of L{\"u}scher-Weisz improvement.
The resulting color-electric energy is an infinite series, which is expected to
be rapidly convergent. For the purpose of practical calculations, we construct
a simpler improved Hamiltonian, which includes only nearest-neighbor
interactions.Comment: 30 pages, LaTe
Assessment of early lung disease in young children with CF: A comparison between pressure-controlled and free-breathing chest computed tomography
Background: Chest computed tomography (CT) in children with cystic fibrosis (CF) is sensitive in detecting early airways disease. The pressure-controlled CT-protocol combines a total lung capacity scan (TLC PC-CT) with a near functional residual capacity scan (FRC PC-CT) under general anesthesia, while another CT-protocol is acquired during free breathing (FB-CT) near functional residual capacity. The aim of this study was to evaluate the sensitivity in detecting airways disease of both protocols in two cohorts. Methods: Routine PC-CTs (Princess Margaret Children's Hospital) and FB-CTs (Erasmus MC—Sophia Children's Hospital) were retrospectively collected from CF children aged 2 to 6 years. Total airways disease (%disease), bronchiectasis (%Bx), and low attenuation regions (%LAR) were scored on CTs using the Perth-Rotterdam annotated grid morphometric analysis-CF method. The Wilcoxon signed-rank test was used for differences between TLC and FRC PC-CTs and the Wilcoxon rank-sum test for differences between FRC PC-CTs and FB-CTs. Results: Fifty patients with PC-CTs (21 male, aged 2.5-5.5 years) and 42 patients with FB-CTs (26 male, aged 2.3-6.8 years) were included. %Disease was higher on TLC PC-CTs compared with FRC PC-CTs (median 4.51 vs 2.49; P <.001). %Disease and %Bx were not significantly different between TLC PC-CTs and FB-CTs (median 4.51% vs 3.75%; P =.143 and 0.52% vs 0.57%; P =.849). %Disease, %Bx, and %LAR were not significantly different between FRC PC-CTs and FB-CTs (median 2.49% vs 3.75%; P =.055, 0.54% vs 0.57%; P =.797, and 2.49% vs 1.53%; P =.448). Conclusions: Our data suggest that FRC PC-CTs are less sensitive than TLC PC-CTs and that FB-CTs have similar sensitivity to PC-CTs in detecting lung disease. FB-CTs seem to be a viable alternative for PC-CTs to track CF lung disease in young patients with CF
The Quantum Interest Conjecture
Although quantum field theory allows local negative energy densities and
fluxes, it also places severe restrictions upon the magnitude and extent of the
negative energy. The restrictions take the form of quantum inequalities. These
inequalities imply that a pulse of negative energy must not only be followed by
a compensating pulse of positive energy, but that the temporal separation
between the pulses is inversely proportional to their amplitude. In an earlier
paper we conjectured that there is a further constraint upon a negative and
positive energy delta-function pulse pair. This conjecture (the quantum
interest conjecture) states that a positive energy pulse must overcompensate
the negative energy pulse by an amount which is a monotonically increasing
function of the pulse separation. In the present paper we prove the conjecture
for massless quantized scalar fields in two and four-dimensional flat
spacetime, and show that it is implied by the quantum inequalities.Comment: 17 pages, Latex, 3 figures, uses eps
miR-23~27~24 clusters control effector T cell differentiation and function
Coordinated repression of gene expression by evolutionarily conserved microRNA (miRNA) clusters and paralogs ensures that miRNAs efficiently exert their biological impact. Combining both loss- and gain-of-function genetic approaches, we show that the miR-23~27~24 clusters regulate multiple aspects of T cell biology, particularly helper T (Th) 2 immunity. Low expression of this miRNA family confers proper effector T cell function at both physiological and pathological settings. Further studies in T cells with exaggerated regulation by individual members of the miR-23~27~24 clusters revealed that miR-24 and miR-27 collaboratively limit Th2 responses through targeting IL-4 and GATA3 in both direct and indirect manners. Intriguingly, although overexpression of the entire miR-23 cluster also negatively impacts other Th lineages, enforced expression of miR-24, in contrast to miR-23 and miR-27, actually promotes the differentiation of Th1, Th17, and induced regulatory T cells, implying that under certain conditions, miRNA families can fine tune the biological effects of their regulation by having individual members antagonize rather than cooperate with each other. Together, our results identify a miRNA family with important immunological roles and suggest that tight regulation of miR-23~27~24 clusters in T cells is required to maintain optimal effector function and to prevent aberrant immune responses
Green and efficient production of octyl hydroxyphenylpropionate using an ultrasound-assisted packed-bed bioreactor
A solvent-free system to produce octyl hydroxyphenylpropionate (OHPP) from p-hydroxyphenylpropionic acid (HPPA) and octanol using immobilized lipase (Novozym(A (R)) 435) as a catalyst in an ultrasound-assisted packed-bed bioreactor was investigated. Response-surface methodology (RSM) and a three-level-three-factor Box-Behnken design were employed to evaluate the effects of reaction temperature (x (1)), flow rate (x (2)) and ultrasonic power (x (3)) on the percentage of molar production of OHPP. The results indicate that the reaction temperature and flow rate were the most important variables in optimizing the production of OHPP. Based on a ridge max analysis, the optimum conditions for OHPP synthesis were predicted to consist of a reaction temperature of 65A degrees C, a flow rate of 0.05 ml/min and an ultrasonic power of 1.74 W/cm(2) with a yield of 99.25%. A reaction was performed under these optimal conditions, and a yield of 99.33 +/- A 0.1% was obtained
Roles of insulin-like growth factor II in cardiomyoblast apoptosis and in hypertensive rat heart with abdominal aorta ligation
Although IGF-II activating the IGF-II receptor signaling pathway has been found to stimulate cardiomyocyte hypertrophy, the role of IGF-II in cardiac cell apoptosis remains unclear. This study aimed to identify the roles of IGF-II and/or IGF-II receptors (IGF-II/IIR) in cardiomyoblast apoptosis and in hypertensive rat hearts with abdominal aorta ligation. Cultured rat heart-derived H9c2 cardiomyoblasts and excised hearts from Sprague-Dawley rats with 0- to 20-day complete abdominal aorta ligation, a model of ANG II elevation and hypertension, were used. IGF-II/IIR expression, caspase activity, DNA fragmentation, and apoptotic cells were measured by RT-PCR, Western blot, agarose gel electrophoresis, and TUNEL assay following various combinations of ANG II, IGF-II/IIR antibody, CsA (calcineurin inhibitor), SP-600125 (JNK inhibitor), SB-203580 (p38 inhibitor), U-0126 (MEK inhibitor), or Staurosporine (PKC inhibitor) in H9c2 cells. ANG II-induced DNA fragmentation and TUNEL-positive cells were blocked by IGF-II/IIR antibodies and antisense IGF-II, but not by IGF-II sense. IGF-II-induced apoptosis was blocked by IGF-IIR antibody and CsA. The increased gene expressions of IGF-II and -IIR induced by ANG II were reversed by U-0126 and Sp600125, respectively. Caspase 8 activities induced by ANG II were attenuated by U-0126, SP-600125, and CsA. DNA fragmentation induced by ANG II was totally blocked by SP-600125, and CsA and was attenuated by U-0126. In rats with 0- to 20-day complete abdominal aorta ligation, the increases in IGF-II/IIR levels in the left ventricle were accompanied by hypertension as well as increases in caspase 9 activities and TUNEL-positive cardiac myocytes. ANG II-induced apoptosis was reversed by IGF-II/IIR blockade and coexisted with increased transactivation of IGF-II and -IIR, which are mediated by ERK and JNK pathways, respectively, both of which further contributed to cardiomyoblast apoptosis via calcineurin signaling. The increased cardiac IGF-II, IGF-IIR, caspase 9, and cellular apoptosis were also found in hypertensive rats with abdominal aorta ligation
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