Comparison of lower limb calibration methods for movement analysis with inertial measurement unit (IMU)

International audienceWearable sensor makes possible today to obtain motion measurement for health monitoring, physical activity assessment, or sport performance evaluation in ecological environment. One of them, the inertial measurement unit (IMU), is extensively used to obtain measurements relative to human motion. The IMU, composed of 3D gyroscope, accelerometer, and generally magnetometer, can be used to provide an orientation in a global coordinate system after fusion of the different sensor data

Physical Layer Specification for Wireless Sensor Networks dedicated to Evaluation of Buildings Energetic Performances

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Pharmacokinetics of the individual enantiomers of vigabatrin in neonates with uncontrolled seizures

The antiepileptic drug vigabatrin (VGB) is a selective irreversible inhibitor of GABA-transaminase. It is administered as a racemic R(−), S(+) mixture, but the pharmacological activity of vigabatrin resides in the S(+) enantiomer and the R(−) enantiomer is inactive. The pharmacokinetic parameters of the two enantiomers have been studied after administration of a single oral 125 mg dose of the racemate to six neonates. The mean values of Cmax and AUC of the S(+) enantiomer were significantly lower (Cmax : 14.0±4.3 mg l−1; AUC: 143±44 mg l−1 h) than those of the R(−) enantiomer (Cmax: 34.1±9.5 mg l−1; AUC: 231±88 mg l−1 h), whereas no significant difference in the time to reach Cmax (S(+): 2.1±1.1 h; R(−): 2.2±1 h) was observed between the two enantiomers. During chronic administration (125 mg twice daily over 4 days), there was no evidence of accumulation of either enantiomer

Influence of concurrent antiepileptic medication on the pharmacokinetics of lamotrigine as add-on therapy in epileptic children

1 Lamotrigine is a new antiepileptic drug, chemically unrelated to currently used antiepileptic medication. Its pharmacokinetics can be influenced by concomitant antiepileptic medication

The effects of fructo-oligosaccharides or whole wheat on the digestive bacterial community of broiler chickens using fingerprint methods

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