91 research outputs found
Recommended from our members
Dielectronic recombination of multiply charged ions
Using a merged electron-ion merged beam apparatus in conjunction with the ORNL EN Tandem Van de Graaff, we have measured dielectronic recombination in ..delta..n = 0 transitions for a number of Li-liked (B/sup 2 +/, C/sup 3 +/, N/sup 4 +/, and O/sup 5 +/), Be-like (C/sup 2 +/, N/sup 3 +/, and O/sup 4 +/), B-like (N/sup 2 +/, O/sup 3 +/, and F/sup 4 +/), and Na-like (P/sup 4 +/, S/sup 5 +/, and Cl/sup 6 +/) ions. The results are compared with theory which includes field enhancement and extension of the more highly charged ions is discussed. 11 refs., 11 figs
Recommended from our members
Cross sections for dielectronic recombination of B/sup 2 +/ and C/sup 3 +/ via 2s. -->. 2p excitation
Dielectronic recombination cross sections for the Li-like ions B/sup 2 +/ and C/sup 3 +/ via 1s/sup 2/2s ..-->.. 1s/sup 2/2p excitation are reported. We observed the amount of electron capture attending the passage of MeV/amu ion beams through a colinear, magnetically-confined, space-charge-limited electron beam as a function of relative energy. The results agree well with distorted wave calculations. 13 references
Association of genetic polymorphisms in the ACE ApoE and TGFb genes with premature ischaemic heart disease.
No description supplie
Synthesis of conjugated-ionic block copolymers by controlled radical polymerization
10.1021/ma020408bMacromolecules362304-310MAMO
A systematic review and network meta-analysis of topical pharmacological, oral pharmacological, physical and combined treatments for acne vulgaris
BackgroundVarious treatments for acne vulgaris exist, but little is known about their comparative effectiveness by acne severity.ObjectivesTo identify best treatments for mild-to-moderate and moderate-to-severe acne, as determined by clinician-assessed morphological features.MethodsWe undertook a systematic review and network meta-analysis of randomised controlled trials (RCTs) assessing topical pharmacological, oral pharmacological, physical and combined treatments for mild-to-moderate and moderate-to-severe acne, published up to May 2020. Outcomes included percentage change in total lesion count from baseline, treatment discontinuation for any reason and due to side effects. Risk of bias was assessed using the Cochrane risk-of-bias tool, and bias-adjustment models. We report below effects versus placebo for treatments with ≥50 observations each.ResultsWe included 179 RCTs with ≈35,000 observations across 49 treatment classes. For mild-to-moderate acne, the most effective options for each treatment type were (mean difference, 95% credible intervals): topical pharmacological - combined retinoid with benzoyl peroxide [BPO] (26.16%, 16.75%-35.36%); physical – chemical peels, e.g. salicylic or mandelic acid (39.70%, 12.54%-66.78%) and photochemical therapy [combined blue/red light] (35.36%, 17.75%-53.08%). Oral pharmacological treatments (e.g. antibiotics, hormonal contraceptives) did not appear to be effective after bias adjustment. BPO and topical retinoids were less tolerated than placebo. For moderate-to-severe acne, the most effective options for each treatment type were: topical pharmacological - combined retinoid with lincosamide [clindamycin] (44.43%, 29.20%-60.02%); oral pharmacological - isotretinoin of total cumulative dose ≥120mg/kg/single course (58.09%, 36.99%-79.29%); physical - photodynamic therapy [light therapy enhanced by a photosensitizing chemical] (40.45%, 26.17%-54.11%); combined - BPO with topical retinoid and oral tetracycline (43.53%, 29.49%-57.70%). Topical retinoids and oral tetracyclines were less tolerated than placebo. Quality of included RCTs was moderate-to-very low, with evidence of inconsistency between direct and indirect evidence. Uncertainty in findings was high, in particular for chemical peels, photochemical and photodynamic therapies. However, conclusions were robust to potential bias in the evidence.ConclusionsTopical pharmacological treatment combinations, chemical peels and photochemical therapy were most effective for mild-to-moderate acne. Topical pharmacological treatment combinations, oral antibiotics combined with topical pharmacological treatments, oral isotretinoin, and photodynamic therapy were most effective for moderate-to-severe acne. Further research is warranted for chemical peels, photochemical and photodynamic therapies for which evidence was more limited
- …