46 research outputs found

    Metal and oxidant free construction of substituted- and/or polycyclic-indoles: a useful alternative to Bischler and related syntheses.

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    A wide range of substituted indoles or polycyclic derivatives containing the indole core are easily accessible by acidic treatment of aromatic amines and 1,2-diaza-1,3-dienes. Unlike the related indole-Bischler synthesis, the regioselectivity of the method here reported is unique and predictable, the yields are generally good and also electron withdrawing substituted indoles are smoothly recovered
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