Ziyapaş kadın

Amédé Victor Guillemine'in Hizmet'te yayımlanan Ziyapaş Kadın adlı romanının ilk ve son tefrikalarıTefrikanın devamına rastlanmamış, tefrika yarım kalmıştır

Absenkungs-, Erosions- und Waermeflussgeschichte des Ruhr-Beckens und des nordoestlichen Rechtsrheinischen Schiefergebirges

The burial and thermal history of Palaeozoic and Mesozoic strata in the Muensterland and Ruhr basin and the northern part of the Rhenish Massif east of the river Rhine was reconstructed applying 1D- and new 2D-forward modelling. The basin evolution model was calibrated using vitrinite reflectance and fluid inclusion data, and results of apatite fission track analysis and Rock-Eval pyrolysis. The 1D-simulation of more than 40 wells and pseudo-wells from the study area led to an understanding of the basin evolution. A 2D-simulation was performed for the northern, 90 kilometre long part of the seismic line DEKORP 2-N which crosses the eastern part of the Muensterland and Ruhr basin and the northern part of the Rhenish Massif east of the river Rhine. (orig./RHM)Available from FIZ Karlsruhe / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

Impact of choice, timing, sequence and combination of broad-spectrum antibiotics on the outcome of allogeneic haematopoietic stem cell transplantation

Recent data link the incidence of intestinal GvHD (iGvHD) after allogeneic haematopoietic stem cell transplantation (aSCT) to exposure with piperacillin-tazobactam or imipenem-cilastatin. To assess relevance of timing, duration, sequence and combination of antibiotic treatment in this setting, we applied a time-dependent model to our aSCT cohort. Patients from the prospective Cologne Cohort of Neutropenic Patients (CoCoNut) undergoing aSCT from January 2007 to April 2013 were included into a time-dependent multivariate Cox proportional hazards regression model with backward-stepwise selection. In 399 eligible patients, cumulative antibiotic exposure (hazard ratio (HR) 2.46; 95% confidence interval (95% CI) 1.59-3.81; P < 0.001) and exposure to sequential treatment with penicillin derivatives and carbapenems (HR 6.22, 95% CI 1.27-30.31), but not to the individual classes, were associated with iGvHD at day 100. Glycopeptides were assessed as a risk factor (HR 3.73, 95% CI 1.51-9.19), but not considered independent, since their use was dependent on previous exposure to penicillin derivatives and carbapenems. Patients with iGvHD presented with increased non-relapse mortality at day 365 (HR 3.51; 95% CI 2.10-5.89; P < 0.001). We identified sequential exposure to penicillin derivatives and carbapenems as well as overall exposure to antibiotics as independent risk factors for iGVHD. Confirmation of these findings in larger, prospective cohorts is necessary

VHE Middleware - Middleware for Virtual Home Environments Schlussbericht

Available from TIB Hannover: F03B536+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Bildung und Forschung, Berlin (Germany)DEGerman