Exploring knowledge value creation practices : an interpretive case study

The gaining popularity of Knowledge Management (KM) has been reinforced by the quest for innovation and value creation. Value creation is grounded in the appropriate combination of human networks, social capital, intellectual capital, and technology assets, facilitated by a culture of change. It is indicated that the future of KM tends to focus on the study of the impact on people in terms of value or knowledge value creation. Because of this, the positive relationship between KM and value creation has been discussed extensively in the literature. However, the majority of the studies on knowledge value creation have been widely undertaken to highlight several case studies demonstrating success in developed countries, whilst very few studies have been done in the cultural context of developing countries. These studies in developing economies have identified several distinctive features, in particularsocio-cultural factors that have an important role and influence in KM practices. A call has been made for further research to explore KM in different organisational and cultural contexts in developing economies. Thailand is an example of a developing country where a number of distinctive socio-cultural features have been identified. It therefore represents an interesting case to conduct a study on the influence of these cultural features on KM practices within an organisational context. The objective of this empirical study is to explore knowledge value creation practices in a Thai organisation. The research adopts an interpretive stance and employs a case studyapproach involving multiple data collection methods. It is based on the researcher's personal expertise and close involvement in the selected case study organisation for over a decade. The study characterises Thai distinctive culture in terms of collectiveness, shyness, conscientiousness and seniority, and indicates that these distinctive socio-cultural features critically influence (a) the social network ties and relationships between employees within and across teams, (b) the resulting level of trust between employees, and (c) the ability to share and create knowledge effectively in the organisational socio-cultural environment. The study is limited to a Thai organisation, but can be generalised to other organisations that exhibit similar characteristics. It provides interesting insights into the socio-cultural factors affecting knowledge management adoption in a Thai organisation and a foundation to further the research on the validation of the theoretical model that emerged from this empirical study

Exploring knowledge value creation practices : an interpretive case study

The gaining popularity of Knowledge Management (KM) has been reinforced by the quest for innovation and value creation. Value creation is grounded in the appropriate combination of human networks, social capital, intellectual capital, and technology assets, facilitated by a culture of change. It is indicated that the future of KM tends to focus on the study of the impact on people in terms of value or knowledge value creation. Because of this, the positive relationship between KM and value creation has been discussed extensively in the literature. However, the majority of the studies on knowledge value creation have been widely undertaken to highlight several case studies demonstrating success in developed countries, whilst very few studies have been done in the cultural context of developing countries. These studies in developing economies have identified several distinctive features, in particular socio-cultural factors that have an important role and influence in KM practices. A call has been made for further research to explore KM in different organisational and cultural contexts in developing economies. Thailand is an example of a developing country where a number of distinctive socio-cultural features have been identified. It therefore represents an interesting case to conduct a study on the influence of these cultural features on KM practices within an organisational context. The objective of this empirical study is to explore knowledge value creation practices in a Thai organisation. The research adopts an interpretive stance and employs a case study approach involving multiple data collection methods. It is based on the researcher's personal expertise and close involvement in the selected case study organisation for over a decade. The study characterises Thai distinctive culture in terms of collectiveness, shyness, conscientiousness and seniority, and indicates that these distinctive socio-cultural features critically influence (a) the social network ties and relationships between employees within and across teams, (b) the resulting level of trust between employees, and (c) the ability to share and create knowledge effectively in the organisational socio-cultural environment. The study is limited to a Thai organisation, but can be generalised to other organisations that exhibit similar characteristics. It provides interesting insights into the socio-cultural factors affecting knowledge management adoption in a Thai organisation and a foundation to further the research on the validation of the theoretical model that emerged from this empirical study.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

In vivo Implantation of a Bovine-Derived Collagen Membrane Leads to Changes in the Physiological Cellular Pattern of Wound Healing by the Induction of Multinucleated Giant Cells: An Adverse Reaction?

The present study evaluated the tissue response toward a resorbable collagen membrane derived from bovine achilles tendon (test group) in comparison to physiological wound healing (control group). After subcutaneous implantation in Wistar rats over 30 days, histochemical and immunohistochemical methods elucidated the cellular inflammatory response, vascularization pattern, membrane protein and cell absorbance capacity. After 30 days, the test-group induced two different inflammatory patterns. On the membrane surface, multinucleated giant cells (MNGCs) were formed after the accumulation of CD-68-positive cells (macrophages), whereas only mononuclear cells (MNCs) were found within the membrane central region. Peri-implant vascularization was significantly enhanced after the formation of MNGCs. No vessels were found within the central region of the membrane. Physiological wound healing revealed no MNGCs at any time point. These dynamic changes in the cellular reaction and vascularization within the test-group are related typical indications of a foreign body reaction. Due to the membrane-specific porosity, mononuclear cells migrated into the central region, and the membrane maintained its integrity over 30 days by showing no breakdown or disintegration. The ex vivo investigation analyzed the interaction between the membrane and a blood concentrate system, liquid platelet-rich fibrin (liquid PRF), derived from human peripheral blood and consisting of platelets, leukocytes and fibrin. PRF penetrated the membrane after just 15 min. The data question the role of biomaterial-induced MNGCs as a pathological reaction and whether this is acceptable to trigger vascularization or should be considered as an adverse reaction. Therefore, further pre-clinical and clinical studies are needed to identify the types of MNGCs that are induced by clinically approved biomaterials