Is the Forest Service Keeping Up With the Times?

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75358/1/j.1541-0072.1995.tb01747.x.pd

Racial, Gender, and Professional Diversification in the Forest Service from 1983 to 1992

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72604/1/j.1541-0072.1995.tb01744.x.pd

Neutral Bystander, Intrusive Micromanager, or Useful Catalyst?

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73380/1/j.1541-0072.1995.tb01746.x.pd

The Forest Service Since the National Forest Management Act. Assessing Bureaucratic Response to External and Internal Forces for Change

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/71743/1/j.1541-0072.1995.tb01740.x.pd

Phase dependent encapsulation and release profile of ZIF-based biocomposites

Biocomposites composed of Zeolitic Imidazolate Frameworks (ZIFs) are generating significant interest due to their facile synthesis, and capacity to protect proteins from harsh environments. Here we systematically varied the composition (i.e. relative amounts of ligand (2-methylimidazole), metal precursor (Zn(OAc)₂·2H₂O), and protein) and post synthetic treatments (i.e. washes with water or water/ethanol) to prepare a series of protein@ZIF biocomposites. These data were used to construct two ternary phase diagrams that showed the synthesis conditions employed gave rise to five different phases including, for the first time, biocomposites based on ZIF-CO₃-1. We examined the influence of the different phases on two properties relevant to drug delivery applications: encapsulation efficiency and release profile. The encapsulation efficiencies of bovine serum albumin and insulin were phase dependent and ranged from 75% to 100%. In addition, release profiles showed that 100% protein release varied between 40 and 300 minutes depending on the phase. This study provides a detailed compositional map for the targeted preparation of ZIF-based biocomposites of specific phases and a tool for the straightforward analysis of the crystalline phases of ZIF based materials (web application named “ZIF phase analysis”). These data will facilitate the progress of ZIF bio-composites in the fields of biomedicine and biotechnology.F. Carraro, M. de J. Velásquez-Hernández, E. Astria, W. Liang, L. Twight C. Parise, M. Ge, Z. Huang, R. Ricco, X. Zou, L. Villanova, C.O. Kappe, C. Doonan and P. Falcar

Phase Dependent Encapsulation and Release Profile of ZIF-Based Biocomposites

Here we systematically varied the composition of the relative amounts of ligand (2-methylimidazole), metal precursor (Zn(OAc)2∙2H2O, and protein to prepare a series of protein@ZIF biocomposites. The effect of post synthetic treatments (i.e. washes with water or water/ethanol) was investigated. The XRD data of the examined samples were used to construct ternary diagrams. Five different phases were identified. The encapsulation efficiency (of bovine serum albumin and insulin) were phase dependent