8 research outputs found
Integrative DNA Methylation and Gene Expression Analyses Identify DNA Packaging and Epigenetic Regulatory Genes Associated with Low Motility Sperm
Get PDFIn previous studies using candidate gene approaches, low sperm count (oligospermia) has been associated with altered sperm mRNA content and DNA methylation in both imprinted and non-imprinted genes. We performed a genome-wide analysis of sperm DNA methylation and mRNA content to test for associations with sperm function. (NCBI 1788). There was a trend among altered expression of these epigenetic regulatory genes and RPMM DNA methylation class.Using integrative genome-wide approaches we identified CpG methylation profiles and mRNA alterations associated with low sperm motility
Comprehensive analysis of histone post-translational modifications in mouse and human male germ cells
Get PDF105 COLOCALISATION OF DIFFERENT MODIFIED HISTONES WITHIN BRDT GENE LOCUS OF SPERM DNA FROM FERTILE AND INFERTILE MEN
No full text682 REDUCED EXPRESSION OF CHROMATIN REMODELLING FACTORS: A REASON FOR ROUND SPERMATID MATURATION ARREST AND IDIOPATHIC MALE INFERTILITY?
No full textPresence of histone H3 acetylated at lysine 9 in male germ cells and its distribution pattern in the genome of human spermatozoa
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