Analysis of overfitting in the regularized Cox model

The Cox proportional hazards model is ubiquitous in the analysis of time-to-event data. However, when the data dimension p is comparable to the sample size $N$, maximum likelihood estimates for its regression parameters are known to be biased or break down entirely due to overfitting. This prompted the introduction of the so-called regularized Cox model. In this paper we use the replica method from statistical physics to investigate the relationship between the true and inferred regression parameters in regularized multivariate Cox regression with L2 regularization, in the regime where both p and N are large but with p/N ~ O(1). We thereby generalize a recent study from maximum likelihood to maximum a posteriori inference. We also establish a relationship between the optimal regularization parameter and p/N, allowing for straightforward overfitting corrections in time-to-event analysis

Discrete Symmetries (C,P,T) in Noncommutative Field Theories

In this paper we study the invariance of the noncmmutative gauge theories under C, P and T transformations. For the noncommutative space (when only the spatial part of $\theta$ is non-zero) we show that NCQED is Parity invariant. In addition, we show that under charge conjugation the theory on noncommutative $R^4_{\theta}$ is transformed to the theory on $R^4_{-\theta}$, so NCQED is a CP violating theory. The theory remains invariant under time reversal if, together with proper changes in fields, we also change $\theta$ by $-\theta$. Hence altogether NCQED is CPT invariant. Moreover we show that the CPT invariance holds for general noncommutative space-time.Comment: Revtex File, 4 pages, no figures, minor changes from previous verion. To appear in Phys. Rev. Let

Use of Mental Imagery in Psychotherapy: A Critical Review

The paper presents arguments in favor of the use of mental imagery for therapeutic purposes. Several existing imagery approaches to psychotherapy are critically examined and suggestions for future inquiry are offered. The intimate relation between imagery and the affective-somatic processes is stressed

Nearing Extremal Intersecting Giants and New Decoupled Sectors in N = 4 SYM

We study near-horizon limits of near-extremal charged black hole solutions to five-dimensional $U(1)^3$ gauged supergravity carrying two charges, extending the recent work of Balasubramanian et.al. We show that there are two near-horizon decoupling limits for the near-extremal black holes, one corresponding to the near-BPS case and the other for the far from BPS case. Both of these limits are only defined on the 10d IIB uplift of the 5d black holes, resulting in a decoupled geometry with a six-dimensional part (conformal to) a rotating BTZ X $S^3$. We study various aspects of these decoupling limits both from the gravity side and the dual field theory side. For the latter we argue that there should be two different, but equivalent, dual gauge theory descriptions, one in terms of the 2d CFT's dual to the rotating BTZ and the other as certain large R-charge sectors of d=4,N =4 U(N) SYM theory. We discuss new BMN-type sectors of the N=4 SYM in the $N\to\infty$ limit in which the engineering dimensions scale as $N^{3/2}$ (for the near-BPS case) and as $N^2$ (for the far from BPS case).Comment: 44 pages, references added, minor change

Measuring emission coordinates in a pulsar-based relativistic positioning system

A relativistic deep space positioning system has been proposed using four or more pulsars with stable repetition rates. (Each pulsar emits pulses at a fixed repetition period in its rest frame.) The positioning system uses the fact that an event in spacetime can be fully described by emission coordinates: the proper emission time of each pulse measured at the event. The proper emission time of each pulse from four different pulsars---interpolated as necessary---provides the four spacetime coordinates of the reception event in the emission coordinate system. If more than four pulsars are available, the redundancy can improve the accuracy of the determination and/or resolve degeneracies resulting from special geometrical arrangements of the sources and the event. We introduce a robust numerical approach to measure the emission coordinates of an event in any arbitrary spacetime geometry. Our approach uses a continuous solution of the eikonal equation describing the backward null cone from the event. The pulsar proper time at the instant the null cone intersects the pulsar world line is one of the four required coordinates. The process is complete (modulo degeneracies) when four pulsar world lines have been crossed by the light cone. The numerical method is applied in two different examples: measuring emission coordinates of an event in Minkowski spacetime using pulses from four pulsars stationary in the spacetime; and measuring emission coordinates of an event in Schwarzschild spacetime using pulses from four pulsars freely falling toward a static black hole. These numerical simulations are merely exploratory, but with improved resolution and computational resources the method can be applied to more pertinent problems. For instance one could measure the emission coordinates, and therefore the trajectory, of the Earth.Comment: 9 pages, 2 figures, v3: replaced with version accepted by Phys. Rev.