Alien Registration- Pooler, Frances C. (Madison, Somerset County)

https://digitalmaine.com/alien_docs/7028/thumbnail.jp

When All Hope is Gone, Trust Then Believe: “At Risk” or “At Potential ?

The Cards of Life, when all hope is gone; trust then believe forces educators to view students differently. The notion that we can’t teach students until we truly begin to know them and they begin to trust us is challenged. The fact that our actions have to align with our words and meaningful conversations and relationships must be established in the classroom. At Risk or At Potential? Every school across the nation have students that struggle, academically, socially or behaviorally. There are a variety of reasons as to why? We can no longer ignore these students and pad the numbers to reflect a great school if all students are not being successful. As administrators, teachers, staff and community support members become involved, it has been clear that the child labeled AT RISK could be viewed as a child AT POTENTIAL. If we looked at these students with a positive tag rather than a negative one, it is highly likely that we would have a different outlook and expectations for their futures

Pupillary light reflex metrics as an objective biomarker for sport-related concussion in elite field hockey

Background Concussion diagnosis is based on subjective assessment of several nonspecifc clinical signs and symptoms with no objective test to aid in diagnosis. The pupillary system, in particular the pupil light refexes (PLR) has attracted plausible consideration in this area, given its complex neural circuitry and autonomic function.Aim To assess the reliability and validity of using the NeurOptics PLR-3000 pupilometer to measure PLR, and to determine normative data for female athletes.Methods A cross sectional cohort study of 33 senior elite female feld hockey athletes (aged 19–34 years) were recruited. Three valid pupillometry readings were acquired, per eye. Measurements of nine PLR metrics were obtained. Reliability was determined using intraclass coefcients, standard error of measurement (SEM), and minimum detectable change (MDC). Between group diferences (concussion history vs. controls) were analysed using non-parametric tests.Results NeurOptics PLR-3000 showed good to excellent reliability for eight PLR metrics derived from the pupilometer [latency, average constriction velocity (ACV), peak constriction velocity (PCV), average dilation velocity (ADV), T75%max. pupil diameter, min. pupil diameter and percent constriction]. There was no statistical diference between any of the PLR metrics in athletes who had a history of concussion and those that had no history of concussion. The two athletes with a recent history of concussion (<3 months) showed trends towards slowed latency, ACV, PCV and ADV when compared to controls.Conclusion This research does not support previous research that the PLR-3000 is an accurate instrument for distinguishing between those with and without a history of concussion. However, the ICC values for intratester reliability were good to excellent for most PLR metrics, with data comparing favourably to normative values previously reported from other populations. Some PLR metrics may distinguish between distinct group of female athletes (recent history of concussion), but this is a small sample size and exploratory in nature. Larger studies are required to confrm its validity and responsiveness

Evaluations of Livestock Protection Dogs for Deterring Deer and Cattle Interactions

Bovine Tuberculosis (bovine TB) in northern Michigan has proven a dilemma necessitating aggressive measures including depopulation of livestock operations, culling of wildlife, banning the feeding of wildlife, and fencing livestock feed with high fences. Bovine TB is believed to be transmitted from white-tailed deer (Odocoileus virginianus) to domestic cattle through feces, urine, saliva, and nasal secretions on contaminated feed (indirect transmission) and from animal to animal (direct transmission). Effective methods for excluding deer from cattle enclosures would minimize the potential for indirect and direct transmission of bovine TB between infected deer and cattle. We combined an idea used historically in Europe to control predation on sheep with the concept of modem frightening devices that often fall short when the motivation of offending species is high. The use of livestock protection dogs (LPDs) seemed like an ideal solution in controlling the transmission of bovine TB from white-tailed deer to cattle. We felt LPDs raised and bonded with cattle would reduce use of cattle pastures and cattle feed by deer and minimize contact between deer and cattle, thereby reducing the potential for the transmission of bovine TB. We evaluated 4 LPDs over a 5-month period utilizing 2 primary data collection methods (direct observations and motion-activated video) on farmed deer facilities in Michigan. Following the initial evaluation of the LPDs, we relocated the dogs to working livestock operations in Michigan for further evaluation to gain an understanding of their practicality and long-term efficacy. Pastures protected by dogs had fewer intrusions by deer, fewer contacts (within 5m) between deer and cattle, and lower use of cattle feed by deer. Overall, we successfully decreased the potential for disease transmission with 66% fewer intrusions by deer into protected pastures, 96% fewer contacts (within 5m) between deer and cattle, and 100% lower use of cattle feed by deer (based of observation data). Livestock protection dogs were more effective in protecting animals and their immediate surroundings than excluding animals from entire study pastures. We found a strong treatment effect within the High Density Site; while within the Very High Density Site, we had high variability within intrusion rates at protected pastures and relatively low use of unprotected pastures resulting in no significant treatment effect. In conclusion, when properly trained and confined with the protected animals, LPDs minimize the potential for livestock to contract bovine TB from infected deer

Theory of Spontaneous Polarization of Endohedral Fullerenes

A pseudo-Jahn-Teller model describing central atom distortions is proposed for endohedral fullerenes of the form A@C$_{60}$ where A is either a rare gas or a metal atom. A critical (dimensionless) coupling $g_c$ is found, below which the symmetric configuration is stable and above which inversion symmetry is broken. Vibronic parameters are given for selected endohedral fullerenes.Comment: 4 pages, REVTEX, 1 Postscript figure. [Phys. Rev. Lett. (in press)

Dynamical Jahn-Teller Effect and Berry Phase in Positively Charged Fullerene I. Basic Considerations

We study the Jahn-Teller effect of positive fullerene ions $^2$C$_{60}^{+}$ and $^1$C$_{60}^{2+}$. The aim is to discover if this case, in analogy with the negative ion, possesses a Berry phase or not, and what are the consequences on dynamical Jahn-Teller quantization. Working in the linear and spherical approximation, we find no Berry phase in $^1$C$_{60}^{2+}$, and presence/absence of Berry phase for coupling of one $L=2$ hole to an $L=4$/$L=2$ vibration. We study in particular the special equal-coupling case ($g_2=g_4$), which is reduced to the motion of a particle on a 5-dimensional sphere. In the icosahedral molecule, the final outcome assesses the presence/absence of a Berry phase of $\pi$ for the $h_u$ hole coupled to $G_g$/$H_h$ vibrations. Some qualitative consequences on ground-state symmetry, low-lying excitations, and electron emission from C$_{60}$ are spelled out.Comment: 31 pages (RevTeX), 3 Postscript figures (uuencoded

Mapping interactions with the chaperone network reveals factors that protect against tau aggregation.

A network of molecular chaperones is known to bind proteins ('clients') and balance their folding, function and turnover. However, it is often unclear which chaperones are critical for selective recognition of individual clients. It is also not clear why these key chaperones might fail in protein-aggregation diseases. Here, we utilized human microtubule-associated protein tau (MAPT or tau) as a model client to survey interactions between ~30 purified chaperones and ~20 disease-associated tau variants (~600 combinations). From this large-scale analysis, we identified human DnaJA2 as an unexpected, but potent, inhibitor of tau aggregation. DnaJA2 levels were correlated with tau pathology in human brains, supporting the idea that it is an important regulator of tau homeostasis. Of note, we found that some disease-associated tau variants were relatively immune to interactions with chaperones, suggesting a model in which avoiding physical recognition by chaperone networks may contribute to disease