Polarimetry of an Intermediate-age Open Cluster: NGC 5617

We present polarimetric observations in the UBVRI bands of 72 stars located in the direction of the medium age open cluster NGC 5617. Our intention is to use polarimetry as a tool membership identification, by building on previous investigations intended mainly to determine the cluster's general characteristics rather than provide membership suitable for studies such as stellar content and metallicity, as well as study the characteristics of the dust lying between the Sun and the cluster. The obsevations were carried out using the five-channel photopolarimeter of the Torino Astronomical Observatory attached to the 2.15m telescope at the Complejo Astron\'omico El Leoncito (CASLEO; Argentina. We are able to add 32 stars to the list of members of NGC 5617, and review the situation for others listed in the literature. In particular, we find that five blue straggler stars in the region of the cluster are located behind the same dust as the member stars are and we confirm the membership of two red giants. The proposed polarimetric memberships are compared with those derived by photometric and kinematical methods, with excellent results. Among the observed stars, we identify 10 with intrinsic polarization in their light. NGC 5617 can be polarimetrically characterized with $P_{max}= 4.40$ and $\theta_{v}= 73^\circ.1$. The spread in polarization values for the stars observed in the direction of the cluster seems to be caused by the uneven distribution of dust in front of the cluster's face. Finally, we find that in the direction of the cluster, the interstellar medium is apparently free of dust, from the Sun's position up to the Carina-Sagittarius arm, where NGC 5617 seems to be located at its farthest border

Broad-band Optical Polarimetric Studies toward the Galactic young star cluster Be 59

We present multiwavelength optical linear polarimetric observations of 69 stars toward the young open cluster Be 59. The observations reveal the presence of three dust layers located at the distances of \sim300, \sim500 and \sim700 pc. The dust layers produce a total polarization Pv \sim 5.5 per cent. The mean values of polarization and polarization angles due to the dust layers are found to increase systematically with distance. We show that polarimetry in combination with the (U - B) - (B - V) colour-colour diagram yields a better identification of cluster members. The polarization measurements suggest that the polarization due the intra-cluster medium is \sim 2.2 per cent. An anomalous reddening law exists for the cluster region, indicating a relatively larger grain size than that in the diffuse ISM. The spatial variation of the polarization and E(B - V) is found to increase with radial distance from the cluster center, whereas the {\theta}v and {\lambda}max are found to decrease with increasing radial distance from the cluster center. About 40 per cent of cluster members show the signatures of either intrinsic polarization or rotation in their polarization angles. There is an indication that the star light of the cluster members might have been depolarized because of non-uniform alignment of dust grains in the foreground dust layers and in the intra-cluster medium.Comment: 22 pages, 14 figures and 7 tables, Accepted in MNRA

Polarization in young open cluster NGC 6823

We present multiwavelength linear polarimetric observations of 104 stars towards the region of young open cluster NGC 6823. The polarization towards NGC 6823 is dominated by foreground dust grains and we found the evidence for the presence of several layers of dust towards the line of sight. The first layer of dust is located approximately within 200 pc towards the cluster, which is much closer to the Sun than the cluster (~ 2.1 kpc). The radial distribution of the position angles for the member stars are found to show a systematic change while the polarization found to reduce towards the outer parts of the cluster and the average position angle of coronal region of the cluster is very close to the inclination of the Galactic parallel (~ 32 degree). The size distribution of the grains within NGC 6823 is similar to those in general interstellar medium. The patchy distribution of foreground dust grains are suggested to be mainly responsible for the both differential reddening and polarization towards NGC 6823. The majority of the observed stars do not show the evidence of intrinsic polarization in their light.Comment: 16 pages, 6 tables, 11 figures, Accepted for publication in MNRA

IDENTIFICAZIONE DELLE LESIONI POLMONARI IN RM CON UNA SEQUENZA VIBE MODIFICATA E CON UNA SEQUENZA VIBE STANDARD: UN CONFRONTO CON LA TC.

Scopo valutare l\u2019accuratezza della RM a 3 Tesla nell\u2019individuazione di lesioni polmonari con una sequenza VIBE modificata e con una sequenza VIBE standard, usando la TC come riferimento. Materiale e metodi abbiamo rivalutato retrospettivamente 37 pazienti oncologici (11 pediatrici e 26 adulti; 19 F) sottoposti a TC e PET/RM da 3T il cui protocollo prevedeva una sequenza VIBE acquisita a respiro trattenuto con echo time (TE) di 0.89 ms e flip angle (FA) di 3\ub0. Le VIBE sono state valutate da tre osservatori per l'identificazione di noduli >5mm o =5mm. Un quarto osservatore ha valutato delle sequenze VIBE standard (TE di 1.2 ms e FA di 10\ub0), anch\u2019esse incluse nel protocollo, ed infine un quinto lettore ha analizzato le immagini TC (considerate come standard di riferimento).Sia per paziente che per singola lesione sono state calcolate sensibilit\ue0 e specificit\ue0 per le due categorie di noduli ed il coefficiente di correlazione intraclasse (ICC) per i lettori delle VIBE modificate. Risultati analisi per paziente (positivit\ue0=1 lesione): sensibilit\ue0 84.6% e specificit\ue0 di 100% per noduli>5mm (VIBE standard 69.2% e 100%) e 44.4% e 100% per noduli=5mm (VIBE standard 33.3% e 100%). Analisi per lesione (presenza/assenza): sensibilit\ue0 di 83.9% per noduli>5mm (VIBE standard 67.74%) e 37.5% per noduli=5mm (VIBE standard 18.7%). L\u2019ICC nell\u2019analisi per paziente era 0.911 per noduli>5mm e 0.902 per noduli=5mm; nell\u2019analisi per lesione 0.866 per noduli>5mm e 0.699 per noduli=5mm. Conclusioni la sequenza VIBE modificata \ue8 riproducibile ed accurata per l\u2019individuazione di noduli >5mm, mentre l\u2019accuratezza risulta meno soddisfacente per i noduli=5mm. L\u2019utilizzo della sequenza modificata nei protocolli RM sembra ragionevole per migliorare la visualizzazione del polmone

ETV6::ABL1-Positive Myeloid Neoplasm: A Case of a Durable Response to Imatinib Mesylate without Additional or Previous Treatment

ETV6::ABL1 rearranged neoplasms are rare hematological diseases. To date, about 80 cases have been reported, including myeloid and lymphoid leukemias. The ETV6 gene codes for an ETS family transcription factor and several fusion partners have been described. When translocated, ETV6 causes the constitutive activation of the partner genes. Here, we report the case of a 54-year-old woman with a cryptic insertion of the 3′ region of ABL1 in the ETV6 gene. The patient was first diagnosed with idiopathic hypereosinophilic syndrome, according to the clinical history, conventional cytogenetics, standard molecular analyses and pathologist description. Next generation sequencing of diagnosis samples unexpectedly detected both ETV6::ABL1 type A and B fusion transcripts, which were then confirmed by FISH. The diagnosis was Myeloid/Lymphoid neoplasm with ETV6::ABL1 fusion, and the patient received imatinib mesylate treatment. In a follow-up after more than one year, the patient still maintained the molecular and complete hematological responses. This case highlights the importance of timely and proper diagnostics and prompt tyrosine kinase inhibitor treatment

Multi-wavelength polarimetric study towards the open cluster NGC 1893

We present multi-wavelength linear polarimetric observations for 44 stars of the NGC 1893 young open cluster region along with V-band polarimetric observations of stars of other four open clusters located between l ~160 to ~175 degree. We found evidence for the presence of two dust layers located at a distance of ~170 pc and ~360 pc. The dust layers produce a polarization Pv ~2.2%. It is evident from the clusters studied in the present work that, in the Galactic longitude range l ~160 to 175 degree and within the Galactic plane (|b| < 2 degree), the polarization angles remain almost constant, with a mean ~163 degree and a dispersion of 6 degree. The small dispersion in polarization angle could be due to the presence of uniform dust layer beyond 1 kpc. Present observations reveal that in case of NGC 1893, the foreground two dust layers, in addition to the intracluster medium, seems to be responsible for the polarization effects. It is also found that towards the direction of NGC 1893, the dust layer that exists between 2-3 kpc has a negligible contribution towards the total observed polarization. The weighted mean for percentage of polarization (Pmax) and the wavelength at maximum polarization ({\lambda}max) are found to be 2.59 \pm 0.02% and 0.55 \pm 0.01 \mum respectively. The estimated mean value of {\lambda}max indicates that the average size of the dust grains within the cluster is similar to that in the general interstellar medium. The spatial variation of the polarization is found to decrease towards the outer region of the cluster. In the present work, we support the notion, as already has been shown in previous studies, that polarimetry, in combination with (U-B)/(B-V) colour-colour diagram, is a useful tool for identifying non-members in a cluster.Comment: 36 pages, 12 figures, 10 tables, accepted for the publication in MNRA

The Web will kill them all: new media, digital utopia, and political struggle in the Italian 5-Star Movement

This article examines the role of discourses about new media technology and the Web in the rise of the 5-Star Movement (Movimento 5 Stelle, or M5S) in Italy. Founded by comedian and activist Beppe Grillo and Web entrepreneur Gianrobe rto Casaleggio in 2009, this movement succeeded in becoming the second largest party at t he 2013 national elections in Italy. This article aims to discuss how elements of digital uto pia and Web-centric discourses have been inserted into the movement’s political message, and how the construction of the Web as a myth has shaped the movement’s discourse and political p ractice. The 5-Star Movement is compared and contrasted with other social and political move ments in Western countries which have displayed a similar emphasis on new media, such as the Occupy movement, the Indignados movement, and the Pirate Parties in Sweden and Germ any. By adopting and mutating cyber- utopian discourses from the so-called Californian i deology, the movement symbolically identifies itself with the Web. The traditional political esta blishment is associated with “old” media (television, radio, and the printed press), and rep resented as a “walking dead,” doomed to be superseded and buried by a Web-based direct democra cy

Disease-specific and general health-related quality of life in newly diagnosed prostate cancer patients: The Pros-IT CNR study

Background: The National Research Council (CNR) prostate cancer monitoring project in Italy (Pros-IT CNR) is an observational, prospective, ongoing, multicentre study aiming to monitor a sample of Italian males diagnosed as new cases of prostate cancer. The present study aims to present data on the quality of life at time prostate cancer is diagnosed. Methods: One thousand seven hundred five patients were enrolled. Quality of life is evaluated at the time cancer was diagnosed and at subsequent assessments via the Italian version of the University of California Los Angeles-Prostate Cancer Index (UCLA-PCI) and the Short Form Health Survey (SF-12). Results: At diagnosis, lower scores on the physical component of the SF-12 were associated to older ages, obesity and the presence of 3+ moderate/severe comorbidities. Lower scores on the mental component were associated to younger ages, the presence of 3+ moderate/severe comorbidities and a T-score higher than one. Urinary and bowel functions according to UCLA-PCI were generally good. Almost 5% of the sample reported using at least one safety pad daily to control urinary loss; less than 3% reported moderate/severe problems attributable to bowel functions, and sexual function was a moderate/severe problem for 26.7%. Diabetes, 3+ moderate/severe comorbidities, T2 or T3-T4 categories and a Gleason score of eight or more were significantly associated with lower sexual function scores at diagnosis. Conclusions: Data collected by the Pros-IT CNR study have clarified the baseline status of newly diagnosed prostate cancer patients. A comprehensive assessment of quality of life will allow to objectively evaluate outcomes of different profile of care

Associations between healthy eating patterns and indicators of metabolic risk in postmenopausal women

<p>Abstract</p> <p>Background</p> <p>Since human diets contain many components that may work synergistically to prevent or promote disease, assessing diet quality may be informative. The purpose of this study was to investigate the association between quality diet, by using Healthy Eating Index (HEI), and metabolic risk indicators in postmenopausal women.</p> <p>Methods</p> <p>This cross-sectional study included a total of 173 Brazilian women, aged 45-75 years, seeking healthcare at a public outpatient center. Food consumption assessed by 24 h-recall food inquiry was used to calculate HEI scores: >80 implied diet good, 80-51 diet "needed improvement", and <51 diet poor. Anthropometric data included: body mass index (BMI = weight/height²), waist-circumference (WC), body fat (%BF) and lean mass (%LM). Data on total cholesterol (TC), high density lipoprotein cholesterol (HDLC), low density lipoprotein cholesterol (LDLC), and triglycerides (TG) were also collected. Fisher's Exact test, and logistic regression method (to determine odds ratio, OR) were used in the statistical analysis.</p> <p>Results</p> <p>Overweight and obesity were observed in 75.7% of the participants. Excessive %BF (> 35%) was observed in 56.1%, while %LM was reduced (< 70%) in 78.1%. WC was elevated (≥88 cm) in 72.3%. Based on HEI values, diet quality was good in 3% (5/173), needed improvement in 48.5% (84/173), and was poor in 48.5% (84/173) of the cases. In this group, 75% of women had high intakes of lipids (> 35%), predominantly saturated and monounsaturated fat. On average, plasma TC, LDLC, and TG levels were higher than recommended in 57.2%, 79.2% and 45.1% of the women, respectively, while HDLC was low in 50.8%. There was association between HEI scores and the %BF that it was higher among women with HEI score < 80 (p = 0.021). There were not observed significant risk associations between HEI and lipid profile.</p> <p>Conclusion</p> <p>Among the Brazilian postmenopausal women attending a public outpatient clinic, diet was considered to need improvement or to be of poor quality, attributed to high saturated fat ingestion, which probably caused a negative impact on metabolic risk indicators, namely body composition.</p