107 research outputs found
Complex systems and the technology of variability analysis
Characteristic patterns of variation over time, namely rhythms, represent a defining feature of complex systems, one that is synonymous with life. Despite the intrinsic dynamic, interdependent and nonlinear relationships of their parts, complex biological systems exhibit robust systemic stability. Applied to critical care, it is the systemic properties of the host response to a physiological insult that manifest as health or illness and determine outcome in our patients. Variability analysis provides a novel technology with which to evaluate the overall properties of a complex system. This review highlights the means by which we scientifically measure variation, including analyses of overall variation (time domain analysis, frequency distribution, spectral power), frequency contribution (spectral analysis), scale invariant (fractal) behaviour (detrended fluctuation and power law analysis) and regularity (approximate and multiscale entropy). Each technique is presented with a definition, interpretation, clinical application, advantages, limitations and summary of its calculation. The ubiquitous association between altered variability and illness is highlighted, followed by an analysis of how variability analysis may significantly improve prognostication of severity of illness and guide therapeutic intervention in critically ill patients
The Role of Husbands’ and Wives’ Emotional Expressivity in the Marital Relationship
The current investigation was designed to examine the role of positive and negative emotional expressivity in the marital relationship. Data from 58 married couples were used to assess spouses’ levels of emotional expressivity and how these levels predicted reports of marital functioning. Regression analyses indicated that positive emotional expressivity had limited influence on marital functioning. Negative expressivity, however, had a strong impact on marital love, conflict, and ambivalence. Post-hoc analyses revealed significant differences between pairings in which the husband was high in negative expressivity, irrespective of wives’ negative emotional expressivity, and pairings in which both partners were low in negative emotional expressivity. These findings are discussed with respect to previous research that suggests that wives’ emotional expressivity is the major determinant of marital functioning.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45641/1/11199_2005_Article_3726.pd
Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system
Increased body fat is associated with potentiation of blood pressure response to hypoxia in healthy men: relations with insulin and leptin
Peak oxygen uptake is not determined by cardiac noradrenaline spillover in heart failure
Limitations of the use of spectral analysis of heart rate variability for the estimation of cardiac sympathetic activity in heart failure
Resting muscle sympathetic nerve activity and peak oxygen uptake in heart failure and normal subjects
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