The incidence of malignancy in the residual rectum of IBD patients after colectomy : a systematic review and meta-analysis

Acknowledgements The authors would like to kindly thank Mr. Rob Polson for his valuable assistance with the search strategy. Funding There was no funding provided for this study.Peer reviewedPublisher PD

Prognostic value of lymph node ratio and extramural vascular invasion on survival for patients undergoing curative colon cancer resection

There was no study funding. We are grateful to Tony Rafferty (Tailored Information for the People of Scotland, TIPs) for providing survival data.Peer reviewedPublisher PD

Perioperative haemodynamic changes in patients undergoing laparoscopic adrenalectomy for phaeochromocytomas and other adrenal tumours

Background: Perioperative haemodynamic changes are well recognised sequelae of adrenalectomy for phaeochromocytomas. The aim of this study was to compare haemodynamic changes in patients undergoing laparoscopic adrenalectomy (LA) for phaeochromocytomas and other adrenal tumours. Method: Patients were identified from a prospective database (Jan 1999-Feb 2008). All patients were managed by a multi-disciplinary team. Haemodynamic variables were: pulse, blood pressure and the requirement of antihypertensive or vasopressor therapies in the perioperative period. Results: Over the nine-year period, 34 consecutive patients underwent laparoscopic phaeo-chromocytoma resection (one patient had delayed contralateral LA) and 104 consecutive patients underwent LA for other tumours (two patients had delayed contralateral LA). 5 out of 35 resections in the phaeochromocytoma group experienced severe hypertension (systolic blood pressure (SBP) greather than 200 mm Hg) compared to two out of 106 resections in the non phaeochromocytoma group (p=0.010). No patient in either group had a transient or persistent (greater than 10 min) SBP greater than 220 mm Hg. Intraoperative antihypertensive Use was significantly increased in the phaeochromocytoma group (p less than 0.005). There were no significant differences between groups for persistent hypotension (SBP less than 80 mm Hg), heart rate greater than 120/min and recovery room haemodynamic parameters. Conclusion: LA for phaeochromocytoma can be accomplished with low perioperative haemodynamic complications when compared to LA for other adrenal tumours