Low-cost composites based on porous titania–apatite surfaces for the removal of patent blue V from water: Effect of chemical structure of dye

Hydroxyapatite/titania nanocomposites (TiHAp) were synthesized from a mixture of a titanium alkoxide solution and dissolution products of a Moroccan natural phosphate. The simultaneous gelation and precipitation processes occurring at room temperature led to the formation of TiHAp nanocomposites. X-ray diffraction results indicated that hydroxyapatite and anatase (TiO2) were the major crystalline phases. The specific surface area of the nanocomposites increased with the TiO2 content. Resulting TiHAp powders were assessed for the removal of the patent blue V dye from water. Kinetic experiments suggested that a sequence of adsorption and photodegradation is responsible for discoloration of dye solutions. These results suggest that such hydroxyapatite/titania nanocomposites constitute attractive low-cost materials for the removal of dyes from industrial textile effluent

High-frequency Si/SiGe phototransistor model: Operation on multiple polarization points

This article presents the results of our research on the modeling of an HPT SiGe heterojunction phototransistor. Usually this HPTs type work for a single point of polarization in this work, we were interested in modeling the same HPT on different points of polarization. We will model the HPT to operate at both 2V and 3V, so that we can use the HPT at multiple bias points and reduce costs and allow the reuse of the HPT SiG heterojunction phototransistor on further studies. For a defined point of polarization we will optimize the operation of the HPT so that it flies with the dynamic measurements and we will not base on this HPT by modifying certain values and components so that the HTP works on the other points of polarization

Evolution of quality of life in patients with breast cancer during the first year of follow-up in Morocco

Abstract Background Quality of life has an important place in the future of patients with breast cancer. The objective of this study is to assess the evolution of the patient’s quality of life with breast cancer in Morocco after a year of follow-up. Methods This study involved the patients with breast cancer with all types of treatment as determined by their physicians. Patient’s quality of life was assessed with the Moroccan Arabic version of QLQ- EORTC QLQ C30 and EORTC-BR23 questionnaires. Data were analyzed using SPSS Version 20 software. Results Regarding EOTRC questionnaires QLQ C-30, there was a significant improvement in global health status and all scales of the functional dimension except the social functional where there was a trend towards improvement and the financial impact of the disease where the situation has deteriorated. Quality of life was improved for most symptom-sized scales dimension of EORTC QLQ- C30 with the exception of diarrhea where it was observed degradation. Most of the EORTC QLQ-scales BR23 questionnaires showed a favorable trend in the quality of life except those of sexual functioning, sexual enjoyment, hair loss and the side effects of systemic therapy. Conclusion The quality of life of the patient is significantly improved after 1 year of follow up. Quality of life instruments can be useful in the early identification of patients whose score low on functional scales and symptoms

Cell-free DNA TAPS provides multimodal information for early cancer detection

Multimodal, genome-wide characterization of epigenetic and genetic information in circulating cell-free DNA (cfDNA) could enable more sensitive early cancer detection, but it is technologically challenging. Recently, we developed TET-assisted pyridine borane sequencing (TAPS), which is a mild, bisulfite-free method for base-resolution direct DNA methylation sequencing. Here, we optimized TAPS for cfDNA (cfTAPS) to provide high-quality and high-depth whole-genome cell-free methylomes. We applied cfTAPS to 85 cfDNA samples from patients with hepatocellular carcinoma (HCC) or pancreatic ductal adenocarcinoma (PDAC) and noncancer controls. From only 10 ng of cfDNA (1 to 3 ml of plasma), we generated the most comprehensive cfDNA methylome to date. We demonstrated that cfTAPS provides multimodal information about cfDNA characteristics, including DNA methylation, tissue of origin, and DNA fragmentation. Integrated analysis of these epigenetic and genetic features enables accurate identification of early HCC and PDAC