Cloaking by coating: How effectively does a thin, stiff coating hide a soft substrate?

From human tissue to fruits, many soft materials are coated by a thin layer of a stiffer material. While the primary role of such a coating is often to protect the softer material, the thin, stiff coating also has an important effect on the mechanical behaviour of the composite material, making it appear significantly stiffer than the underlying material. We study this cloaking effect of a coating for the particular case of indentation tests, which measure the `firmness' of the composite solid: we use a combination of theory and experiment to characterize the firmness quantitatively. We find that the indenter size plays a key role in determining the effectiveness of cloaking: small indenters feel a mixture of the material properties of the coating and of the substrate, while large indenters sense largely the unadulterated substrate

DC-Prophet: Predicting Catastrophic Machine Failures in DataCenters

When will a server fail catastrophically in an industrial datacenter? Is it possible to forecast these failures so preventive actions can be taken to increase the reliability of a datacenter? To answer these questions, we have studied what are probably the largest, publicly available datacenter traces, containing more than 104 million events from 12,500 machines. Among these samples, we observe and categorize three types of machine failures, all of which are catastrophic and may lead to information loss, or even worse, reliability degradation of a datacenter. We further propose a two-stage framework-DC-Prophet-based on One-Class Support Vector Machine and Random Forest. DC-Prophet extracts surprising patterns and accurately predicts the next failure of a machine. Experimental results show that DC-Prophet achieves an AUC of 0.93 in predicting the next machine failure, and a F3-score of 0.88 (out of 1). On average, DC-Prophet outperforms other classical machine learning methods by 39.45% in F3-score.Comment: 13 pages, 5 figures, accepted by 2017 ECML PKD

Kepler-447b: a hot-Jupiter with an extremely grazing transit

We present the radial velocity confirmation of the extrasolar planet Kepler-447b, initially detected as a candidate by the Kepler mission. In this work, we analyze its transit signal and the radial velocity data obtained with the Calar Alto Fiber-fed Echelle spectrograph (CAFE). By simultaneously modeling both datasets, we obtain the orbital and physical properties of the system. According to our results, Kepler-447b is a Jupiter-mass planet ($M_p=1.37^{+0.48}_{-0.46}~M_{\rm Jup}$), with an estimated radius of $R_p=1.65^{+0.59}_{-0.56}~R_{\rm Jup}$ (uncertainties provided in this work are $3\sigma$ unless specified). This translates into a sub-Jupiter density. The planet revolves every $\sim7.8$ days in a slightly eccentric orbit ($e=0.123^{+0.037}_{-0.036}$) around a G8V star with detected activity in the Kepler light curve. Kepler-447b transits its host with a large impact parameter ($b=1.076^{+0.112}_{-0.086}$), being one of the few planetary grazing transits confirmed so far and the first in the Kepler large crop of exoplanets. We estimate that only around 20% of the projected planet disk occults the stellar disk. The relatively large uncertainties in the planet radius are due to the large impact parameter and short duration of the transit. Planets with such an extremely large impact parameter can be used to detect and analyze interesting configurations such as additional perturbing bodies, stellar pulsations, rotation of a non-spherical planet, or polar spot-crossing events. All these scenarios would periodically modify the transit properties (depth, duration, and time of mid-transit), what could be detectable with sufficient accurate photometry. Short-cadence photometric data (at the 1 minute level) would help in the search for these exotic configurations in grazing planetary transits like that of Kepler-447b.Comment: Accepted for publication in A&A. 13 pages, 8 figures, 4 tables. This version replaces an earlier version of the pape

The lice (Insecta : phthiraptera) of short-tailed shearwaters, ardenna tenuirostris, in Bass Strait, Tasmania

There is a paucity of research into the louse fauna of Shorttailed Shearwaters, Ardenna tenuirostris (Temminck, 1835), despite this species being one of the world's most studied seabirds (Bradley et al. 1991 and references therein). Research has been undertaken on these shearwaters at their breeding grounds in Bass Strait, Tasmania, since 1947 (Bradley et al. 1991). As Short-tailed Shearwaters are long-lived, with an estimated average longevity of 38 years (Skira et al. 1985), they may offer a long-term host potential to host-dependent ectoparasites (i.e., lice) (Crompton 1997). Also, with approximately 23 million shearwaters breeding in burrows in dense rookeries on the islands and headlands of southern Australia, from southern New South Wales to Tasmania and from Victoria to Western Australia (Marchant & Higgins 1990), there may be the potential for increased transmission of ectoparasites between individual birds. Increased infestation rates by lice have been shown in colonial living birds. For instance, Rozsa et al. (1996) found an increase in louse infestation on Colonial Rooks, Corvus frugilegus Linnaeus, 1758, as compared to the territorial Hooded Crow, Corvus corone cornix Linnaeus, 1758. Short-tailed Shearwaters undertake an annual transequatorial migration to the Bering Sea for the austral winter (Serventy 1967), and so may act as vectors for the transmission of parasites across hemispheres (Lopez et al. 2005, Price et al. 2003). There are three publications that list the lice of Shorttailed Shearwaters. Green & Munday (1971) were the first to document the ectoparasites of Tasmanian fauna, albeit from personal communications- no published literature was cited. Twenty years later, Green & Palma (1991) listed the lice of Tasmania's vertebrates. They essentially used Green & Munday's (1971) list of lice on shearwaters and added Austromenopon paululum, listed as Austromenopon sp. in Green & Munday (1971). Price et al. (2003), in their checklist of the chewing lice (Phthiraptera) of the world, also listed the lice of Short -tailed Shearwaters. Included in this list were two louse species, Naubates harrisoni (Bedford, 1930) and Ancistrona vagelli (Fabricus, 1787), not mentioned in Green & Munday (1971). As part of the long-term research into Bass Strait's Short-tailed Shearwaters, this study aimed to confirm their current louse fauna, detailing the specific location, and collection method, to fill a gap in the primary literature

Kepler-91b: a planet at the end of its life. Planet and giant host star properties via light-curve variations

The evolution of planetary systems is intimately linked to the evolution of their host star. Our understanding of the whole planetary evolution process is based on the large planet diversity observed so far. To date, only few tens of planets have been discovered orbiting stars ascending the Red Giant Branch. Although several theories have been proposed, the question of how planets die remains open due to the small number statistics. In this work we study the giant star Kepler-91 (KOI-2133) in order to determine the nature of a transiting companion. This system was detected by the Kepler Space Telescope. However, its planetary confirmation is needed. We confirm the planetary nature of the object transiting the star Kepler-91 by deriving a mass of $M_p=0.88^{+0.17}_{-0.33} ~M_{\rm Jup}$ and a planetary radius of $R_p=1.384^{+0.011}_{-0.054} ~R_{\rm Jup}$. Asteroseismic analysis produces a stellar radius of $R_{\star}=6.30\pm 0.16 ~R_{\odot}$ and a mass of $M_{\star}=1.31\pm 0.10 ~ M_{\odot}$. We find that its eccentric orbit ($e=0.066^{+0.013}_{-0.017}$) is just $1.32^{+0.07}_{-0.22} ~ R_{\star}$ away from the stellar atmosphere at the pericenter. Kepler-91b could be the previous stage of the planet engulfment, recently detected for BD+48 740. Our estimations show that Kepler-91b will be swallowed by its host star in less than 55 Myr. Among the confirmed planets around giant stars, this is the planetary-mass body closest to its host star. At pericenter passage, the star subtends an angle of $48^{\circ}$, covering around 10% of the sky as seen from the planet. The planetary atmosphere seems to be inflated probably due to the high stellar irradiation.Comment: 21 pages, 8 tables and 11 figure

Six Peaks Visible in the Redshift Distribution of 46,400 SDSS Quasars Agree with the Preferred Redshifts Predicted by the Decreasing Intrinsic Redshift Model

The redshift distribution of all 46,400 quasars in the Sloan Digital Sky Survey (SDSS) Quasar Catalog III, Third Data Release, is examined. Six Peaks that fall within the redshift window below z = 4, are visible. Their positions agree with the preferred redshift values predicted by the decreasing intrinsic redshift (DIR) model, even though this model was derived using completely independent evidence. A power spectrum analysis of the full dataset confirms the presence of a single, significant power peak at the expected redshift period. Power peaks with the predicted period are also obtained when the upper and lower halves of the redshift distribution are examined separately. The periodicity detected is in linear z, as opposed to log(1+z). Because the peaks in the SDSS quasar redshift distribution agree well with the preferred redshifts predicted by the intrinsic redshift relation, we conclude that this relation, and the peaks in the redshift distribution, likely both have the same origin, and this may be intrinsic redshifts, or a common selection effect. However, because of the way the intrinsic redshift relation was determined it seems unlikely that one selection effect could have been responsible for both.Comment: 12 pages, 12 figure, accepted for publication in the Astrophysical Journa

Retrodiction as a tool for micromaser field measurements

We use retrodictive quantum theory to describe cavity field measurements by successive atomic detections in the micromaser. We calculate the state of the micromaser cavity field prior to detection of sequences of atoms in either the excited or ground state, for atoms that are initially prepared in the excited state. This provides the POM elements, which describe such sequences of measurements.Comment: 20 pages, 4(8) figure

Baseline T cell dysfunction by single cell network profiling in metastatic breast cancer patients.

BackgroundWe previously reported the results of a multicentric prospective randomized trial of chemo-refractory metastatic breast cancer patients testing the efficacy of two doses of TGFβ blockade during radiotherapy. Despite a lack of objective responses to the combination, patients who received a higher dose of TGFβ blocking antibody fresolimumab had a better overall survival when compared to those assigned to lower dose (hazard ratio of 2.73, p = 0.039). They also demonstrated an improved peripheral blood mononuclear cell (PBMC) counts and increase in the CD8 central memory pool. We performed additional analysis on residual PBMC using single cell network profiling (SCNP).MethodsThe original trial randomized metastatic breast cancer patients to either 1 or 10 mg/kg of fresolimumab, every 3 weeks for 5 cycles, combined with radiotherapy to a metastatic site at week 1 and 7 (22.5 Gy given in 3 doses of 7.5 Gy). Trial immune monitoring results were previously reported. In 15 patients with available residual blood samples, additional functional studies were performed, and compared with data obtained in parallel from seven healthy female donors (HD): SCNP was applied to analyze T cell receptor (TCR) modulated signaling via CD3 and CD28 crosslinking and measurement of evoked phosphorylation of AKT and ERK in CD4 and CD8 T cell subsets defined by PD-1 expression.ResultsAt baseline, a significantly higher level of expression (p < 0.05) of PD-L1 was identified in patient monocytes compared to HD. TCR modulation revealed dysfunction of circulating T-cells in patient baseline samples as compared to HD, and this was more pronounced in PD-1+ cells. Treatment with radiotherapy and fresolimumab did not resolve this dyfunctional signaling. However, in vitro PD-1 blockade enhanced TCR signaling in patient PD-1+ T cells and not in PD-1- T cells or in PD-1+ T cells from HD.ConclusionsFunctional T cell analysis suggests that baseline T cell functionality is hampered in metastatic breast cancer patients, at least in part mediated by the PD-1 signaling pathway. These preliminary data support the rationale for investigating the possible beneficial effects of adding PD-1 blockade to improve responses to TGFβ blockade and radiotherapy.Trial registrationNCT01401062