The pharmaceutical use of permethrin: Sources and behavior during municipal sewage treatment

This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2010 Springer Science+Business Media, LLC.Permethrin entered use in the 1970s as an insecticide in a wide range of applications, including agriculture, horticultural, and forestry, and has since been restricted. In the 21st century, the presence of permethrin in the aquatic environment has been attributed to its use as a human and veterinary pharmaceutical, in particular as a pedeculicide, in addition to other uses, such as a moth-proofing agent. However, as a consequence of its toxicity to fish, sources of permethrin and its fate and behavior during wastewater treatment are topics of concern. This study has established that high overall removal of permethrin (approximately 90%) was achieved during wastewater treatment and that this was strongly dependent on the extent of biological degradation in secondary treatment, with more limited subsequent removal in tertiary treatment processes. Sources of permethrin in the catchment matched well with measured values in crude sewage and indicated that domestic use accounted for more than half of the load to the treatment works. However, removal may not be consistent enough to achieve the environmental quality standards now being derived in many countries even where tertiary treatment processes are applied.United Utilities PL

Energy Proportionality and Workload Consolidation for Latency-Critical Applications

Energy proportionality and workload consolidation are important objectives towards increasing efficiency in large-scale datacenters. Our work focuses on achieving these goals in the presence of applications with microsecond-scale tail latency requirements. Such applications represent a growing subset of datacenter workloads and are typically deployed on dedicated servers, which is the simplest way to ensure low tail latency across all loads. Unfortunately, it also leads to low energy efficiency and low resource utilization during the frequent periods of medium or low load. We present the OS mechanisms and dynamic control needed to adjust core allocation and voltage/frequency settings based on the measured delays for latency-critical workloads. This allows for energy proportionality and frees the maximum amount of resources per server for other background applications, while respecting service-level objectives. The two key mechanism allow us to detect increases in queuing latencies and to re-assign flow groups between the threads of a latency-critical application in milliseconds without dropping or reordering packets. We compare the efficiency of our solution to the Pareto-optimal frontier of 224 distinct static configurations. Dynamic resource control saves 44%–54% of processor energy, which corresponds to 85%–93% of the Pareto-optimal upper bound. Dynamic resource control also allows background jobs to run at 32%–46% of their standalone throughput, which corresponds to 82%–92% of the Pareto bound